移植免疫

2022 - Present
日本組織適合性学会, 学術奨励賞選定委員（2022年度、2025年度）

Sep. 2020 - Present
日本組織適合性学会, 評議委員

Apr. 2016 - Present
日本移植学会, トランスレーショナルリサーチ委員

Apr. 2015 - Present
日本臓器保存生物医学会, 評議委員

2014 - Present
日本移植学会, 評議委員

Sep. 2023
大会長賞, 第31回日本組織適合性学会
岩﨑研太

Feb. 2023
優秀演題賞, 第25回日本異種移植研究会
岩﨑研太

Sep. 2017
学術奨励賞, 日本組織適合性学会
岩﨑 研太

Oct. 2016
研究奨励賞, 日本臓器保存生物医学会
岩﨑 研太

Dec. 2012
優秀演題賞, 第14回日本異種移植研究会
岩﨑 研太

Which is more important for;predicting de novo DSA production;in;donor-sensitized kidney transplant recipients, B-cell epitope or T-cell epitope analysis?
Satoshi Ashimine; Shintaro Sakamoto; Toshihide Tomosugi; Eric Spierings; Matthias Niemann; Masato Shizuku; Manabu Okada; Yuko Miwa; Kenta Iwasaki; Takahisa Hiramitsu; Norihiko Goto; Shunji Narumi; Yoshihiko Watarai; Kohei Ishiyama; Takaaki Kobayashi
Human Immunology, Oct. 2024, Reviewed

C1q binding ability for prior risk assessment of antibody-mediated rejection in ABOincompatible kidney transplantation
Yuko Miwa; Kenta Iwasaki; Kenta Murotani; Manabu Okada; Takaharu Nagaska; Yoshihiko Watarai; Asami Takeda; Masato Shizuku; Satoshi Ashimine; Kohei Ishiyama; Shoichi Maruyama; Takaaki Kobayashi
Transplant International, Oct. 2024, Reviewed

Human RP105 monoclonal antibody enhances antigen-specific antibody production in unique culture conditions
Tatsuya Yamazaki; Kenta Iwasaki; Susumu Tomono; Masaki Imai; Yuko Miwa; Masato Shizuku; Satoshi Ashimine; Kohei Ishiyama; Masanori Inui; Daisuke Okuzaki; Manabu Okada; Takaaki Kobayashi; Sachiko Akashi-Takamura
iScience, Sep. 2024, Reviewed
Corresponding, 27(9), 10.1016/j.isci.2024.110649

Estimation of Sensitization Status in Renal Transplant Recipients by Assessing Indirect Pathway CD4+ T cell Response to Donor Cell-pulsed Dendritic Cell
Iwasaki Kenta; Tomosugi Toshihide; Sekiya Takashi; Sakamoto Shintaro; Miwa Yuko; Okada Manabu; Hiramitsu Takahisa; Goto Norihiko; Narumi Shunji; Watarai Yoshihiko; Okumura Mai; Ashimine Satoshi; Ishiyama Kohei; Mohamed B. Ezzelarab; Kobayashi Takaaki
Transplantation, Feb. 2023, Reviewed
Lead, (5), 1079, 1088, 10.1097/tp.0000000000004491

Clostridium butyricum-induced ω-3 fatty acid 18-HEPE elicits anti-influenza virus pneumonia effects through interferon-λ upregulation.
Mao Hagihara; Makoto Yamashita; Tadashi Ariyoshi; Shuhei Eguchi; Ayaka Minemura; Daiki Miura; Seiya Higashi; Kentaro Oka; Tsunemasa Nonogaki; Takeshi Mori; Kenta Iwasaki; Jun Hirai; Yuichi Shibata; Takumi Umemura; Hideo Kato; Nobuhiro Asai; Yuka Yamagishi; Akinobu Ota; Motomichi Takahashi; Hiroshige Mikamo
Cell reports, Dec. 2022, Reviewed
41(11), 111755, 111755, 10.1016/j.celrep.2022.111755

Clostridium butyricum enhances colonization resistance against Clostridioides difficile by metabolic and immune modulation
Mao Hagihara, Tadashi Ariyoshi, Yasutoshi Kuroki, Shuhei Eguchi, Seiya Higashi, Takeshi Mori, Tsunemasa Nonogaki, Kenta Iwasaki, Makoto Yamashita, Nobuhiro Asai, Yusuke Koizumi, Kentaro Oka, Motomichi Takahashi, Yuka Yamagishi, Hiroshige Mikamo
Scientific Reports, Jul. 2021, Reviewed
11(1), 15007, 15007, 10.1038/s41598-021-94572-z

Improved detection of donor-specific HLA-class II antibody in kidney transplant recipients by modified immunocomplex capture fluorescence analysis.
Shuichi Shimabukuro; Kenta Iwasaki; Shintaro Kawai; Takayuki Shirouzu; Yuko Miwa; Yusuke Iida; Fumiaki Nakajima; Kosei Horimi; Yutaka Matsuoka; Satoshi Ashimine; Kohei Ishiyama; Takaaki Kobayashi
Transplant immunology, May 2021, Reviewed, No invitation
Corresponding, 67, 101418, 101418, 10.1016/j.trim.2021.101418

Clinical Significance of Shared T Cell Epitope Analysis in Early De Novo Donor-Specific Anti-HLA Antibody Production After Kidney Transplantation and Comparison With Shared B cell Epitope Analysis.
Toshihide Tomosugi; Kenta Iwasaki; Shintaro Sakamoto; Matthias Niemann; Eric Spierings; Isao Nahara; Kenta Futamura; Manabu Okada; Takahisa Hiramitsu; Asami Takeda; Norihiko Goto; Shunji Narumi; Yoshihiko Watarai; Takaaki Kobayashi
Frontiers in immunology, 2021, Reviewed, No invitation
12, 621138, 621138, 10.3389/fimmu.2021.621138

Molecular Mechanisms of Antibody-Mediated Rejection and Accommodation in Organ Transplantation
Iwasaki Kenta; Kobayashi Takaaki
Nephron, Nov. 2020, Reviewed, Invited
Lead, 144 Suppl 1, 1, 5, 10.1159/000510747

Clostridium butyricum MIYAIRI 588-Induced Protectin D1 Has an Anti-inflammatory Effect on Antibiotic-Induced Intestinal Disorder.
Tadashi Ariyoshi; Mao Hagihara; Shuhei Eguchi; Aiki Fukuda; Kenta Iwasaki; Kentaro Oka; Motomichi Takahashi; Yuka Yamagishi; Hiroshige Mikamo
Frontiers in microbiology, Oct. 2020, Reviewed
11, 587725, 587725, 10.3389/fmicb.2020.587725

Analysis of T and B Cell Epitopes to Predict the Risk of de novo Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study.
Shintaro Sakamoto; Kenta Iwasaki; Toshihide Tomosugi; Matthias Niemann; Eric Spierings; Yuko Miwa; Kosei Horimi; Asami Takeda; Norihiko Goto; Shunji Narumi; Yoshihiko Watarai; Takaaki Kobayashi
Frontiers in immunology, Aug. 2020, Reviewed, No invitation
11, 10.3389/fimmu.2020.02000

The suppressive effect on CD4 T-cell alloresponse against endothelial HLA-DR via PD-L1 induced by anti-A/B ligation.
Kenta Iwasaki; Hiroshi Hamana; Hiroyuki Kishi; Takayuki Yamamoto; Takahisa Hiramitsu; Manabu Okad; Toshihide Tomosugi; Asami Takeda; Shunji Narumi; Yoshihiko Watarai; Yuko Miwa; Mai Okumura; Yutaka Matsuoka; Kosei Horimi; Atsushi Muraguchi; Takaaki Kobayash
Clinical and experimental immunology, Jun. 2020, Reviewed, No invitation
Lead, 10.1111/cei.13482

Interferon-γ-induced HLA Class II expression on endothelial cells is decreased by inhibition of mTOR and HMG-CoA reductase.
Akihiro Maenaka; Iwasaki Kenta; Akinobu Ota; Yuko Miwa; Wataru Ohashi; Kosei Horimi; Yutaka Matsuoka; Masafumi Ohnishi; Kazuharu Uchida; Takaaki Kobayashi
FEBS open bio, Mar. 2020, Reviewed, No invitation
Corresponding, 10(5), 927, 936, 10.1002/2211-5463.12854

Clostridium butyricum Modulates the Microbiome to Protect Intestinal Barrier Function in Mice with Antibiotic-Induced Dysbiosis.
Mao Hagihara; Yasutoshi Kuroki; Tadashi Ariyoshi; Seiya Higashi; Kazuo Fukuda; Rieko Yamashita; Asami Matsumoto; Takeshi Mori; Kaoru Mimura; Naoko Yamaguchi; Shoshiro Okada; Tsunemasa Nonogaki; Tadashi Ogawa; Kenta Iwasaki; Susumu Tomono; Nobuhiro Asai; Yusuke Koizumi; Kentaro Oka; Yuka Yamagishi; Motomichi Takahashi; Hiroshige Mikamo
iScience, Jan. 2020, Reviewed, No invitation
23(1), 100772, 100772, 10.1016/j.isci.2019.100772

Suppressive Effect of Everolimus on IL-2, IL-10, IL-21, and IFNγ Levels: Implications for the Successful Minimization of Calcineurin Inhibitor Use in Transplantation.
Kenta Iwasaki; Nana Kitahata; Yuko Miwa; Kazuharu Uchida; Yutaka Matsuoka; Kosei Horimi; Takaaki Kobayashi
Therapeutic drug monitoring, Jun. 2019, Reviewed, No invitation
Lead, 41(3), 371, 375, 10.1097/FTD.0000000000000630

Lower incidence of de novo donor-specific antibodies against HLA-DR in ABO-incompatible renal transplantation.
Manabu Okada; Yoshihiko Watarai; Kenta Iwasaki; Kenta Futamura; Takayuki Yamamoto; Takahisa Hiramitsu; Makoto Tsujita; Norihiko Goto; Shunji Narumi; Asami Takeda; Takaaki Kobayashi
Human immunology, Mar. 2019, Reviewed, No invitation
80(3), 169, 175, 10.1016/j.humimm.2018.12.004

Increased CD40L+PD-1+ follicular helper T cells (Tfh) as a biomarker for predicting calcineurin inhibitor sensitivity against Tfh-mediated B-cell activation/antibody production after kidney transplantation.
Kenta Iwasaki; Nana Kitahata; Takahisa Hiramitsu; Takayuki Yamamoto; Takayuki Noda; Manabu Okada; Shunji Narumi; Yoshihiko Watarai; Yuko Miwa; Kazuharu Uchida; Yutaka Matsuoka; Kosei Horimi; Takaaki Kobayashi
International immunology, Jul. 2018, Reviewed, No invitation
Lead, 30(8), 345, 355, 10.1093/intimm/dxy039

Peripheral blood immune response-related gene analysis for evaluating the potential risk of chronic antibody-mediated rejection.
Takayuki Yamamoto; Kenta Iwasaki; Kenta Murotani; Asami Takeda; Kenta Futamura; Manabu Okada; Makoto Tsujita; Takahisa Hiramitsu; Norihiko Goto; Shunji Narumi; Yoshihiko Watarai; Kunio Morozumi; Kazuharu Uchida; Takaaki Kobayashi
Human immunology, Jun. 2018, Reviewed, No invitation
79(6), 432, 438, 10.1016/j.humimm.2018.03.012

Favorable results in ABO-incompatible renal transplantation without B cell-targeted therapy: Advantages and disadvantages of rituximab pretreatment.
Manabu Okada; Yoshihiko Watarai; Kenta Iwasaki; Kenta Murotani; Kenta Futamura; Takayuki Yamamoto; Takahisa Hiramitsu; Makoto Tsujita; Norihiko Goto; Shunji Narumi; Asami Takeda; Kunio Morozumi; Kazuharu Uchida; Takaaki Kobayashi
Clinical transplantation, Oct. 2017, Reviewed, No invitation
31(10), 10.1111/ctr.13071

MiR-142-5p and miR-486-5p as biomarkers for early detection of chronic antibody-mediated rejection in kidney transplantation.
Kenta Iwasaki; Takayuki Yamamoto; Yukiko Inanaga; Takahisa Hiramitsu; Yuko Miwa; Kenta Murotani; Shuji Narumi; Yoshihiko Watarai; Akio Katayama; Kazuharu Uchida; Takaaki Kobayashi
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, Feb. 2017, Reviewed, No invitation
Lead, 22(1), 45, 54, 10.1080/1354750X.2016.1204000

Negative regulation of HLA-DR expression on endothelial cells by anti-blood group A/B antibody ligation and mTOR inhibition.
Kenta Iwasaki; Yuko Miwa; Kazuharu Uchida; Yasuhiro Kodera; Takaaki Kobayashi
Transplant immunology, Feb. 2017, Reviewed, No invitation
40, 22, 30, 10.1016/j.trim.2016.12.004

5-year follow-up of a randomized clinical study comparing everolimus plus reduced-dose cyclosporine with mycophenolate mofetil plus standard-dose cyclosporine in de novo kidney transplantation: Retrospective single center assessment.
Takahisa Hiramitsu; Manabu Okada; Kenta Futamura; Takayuki Yamamoto; Makoto Tsujita; Norihiko Goto; Shunji Narumi; Yoshihiko Watarai; Asami Takeda; Kenta Iwasaki; Kazuharu Uchida; Takaaki Kobayashi
International immunopharmacology, Oct. 2016, Reviewed, No invitation
39, 192, 198, 10.1016/j.intimp.2016.07.019

Changes in ABCB1 mRNA Expression in Peripheral Blood Cells before and after Renal Transplantation.
Hideyuki Kushihara; Takafumi Kuzuya; Yuko Miwa; Kenta Iwasaki; Yoshihiko Watarai; Kazuharu Uchida; Kiyofumi Yamada; Takaaki Kobayashi
Biological & pharmaceutical bulletin, 2016, Reviewed, No invitation
39(7), 1085, 90, 10.1248/bpb.b15-00690

Functional difference between membrane-bound and soluble human thrombomodulin.
Yuko Miwa; Satoko Yazaki; Masaki Iwamoto; Shunichi Suzuki; Kenta Iwasaki; Masataka Haneda; Koji Yamamoto; Shoichi Maruyama; Akira Onishi; Takaaki Kobayashi
Transplantation, Apr. 2015, Reviewed, No invitation
99(4), 702, 9, 10.1097/TP.0000000000000571

Clinical relevance of post-transplant pharmacodynamic analysis of cyclosporine in renal transplantation.
Yoko Kurata; Takafumi Kuzuya; Yuko Miwa; Kenta Iwasaki; Masataka Haneda; Katsuo Amioka; Kiyofumi Yamada; Yoshihiko Watarai; Akio Katayama; Kazuharu Uchida; Takaaki Kobayashi
International immunopharmacology, Oct. 2014, Reviewed, No invitation
22(2), 384, 91, 10.1016/j.intimp.2014.07.022

Influence of olive-derived hydroxytyrosol on the toll-like receptor 4-dependent inflammatory response of mouse peritoneal macrophages.
Yohei Takeda; Vuong N Bui; Kenta Iwasaki; Takaaki Kobayashi; Haruko Ogawa; Kunitoshi Imai
Biochemical and biophysical research communications, Apr. 2014, Reviewed, No invitation
446(4), 1225, 30, 10.1016/j.bbrc.2014.03.094

Comparative analysis of drug action on B-cell proliferation and differentiation for mycophenolic acid, everolimus, and prednisolone.
Masataka Haneda; Mami Owaki; Takafumi Kuzuya; Kenta Iwasaki; Yuko Miwa; Takaaki Kobayashi
Transplantation, Feb. 2014, Reviewed, No invitation
97(4), 405, 12, 10.1097/01.TP.0000441826.70687.f6

AMP-activated protein kinase as a promoting factor, but complement and thrombin as limiting factors for acquisition of cytoprotection: implications for induction of accommodation.
Kenta Iwasaki; Yuko Miwa; Masataka Haneda; Takafumi Kuzuya; Haruko Ogawa; Akira Onishi; Takaaki Kobayashi
Transplant international : official journal of the European Society for Organ Transplantation, Nov. 2013, Reviewed, No invitation
26(11), 1138, 48, 10.1111/tri.12186

Transcriptional regulation of the human ferritin gene by coordinated regulation of Nrf2 and protein arginine methyltransferases PRMT1 and PRMT4.
Bo-Wen Huang; Paul D Ray; Kenta Iwasaki; Yoshiaki Tsuji
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Sep. 2013, Reviewed, No invitation
27(9), 3763, 74, 10.1096/fj.12-226043

Comparative study on donor ABO antigen expression levels in red blood cells, platelets and graft endothelial cells
Miwa Yuko; Yamamoto Takayuki; Sawa Yuriko; Iwasaki Kenta; Haneda Masataka; Goto Norihiko; Watarai Yoshihiko; Takeda Asami; Morozumi Kunio; Maruyama Shoichi; Uchida Kazuharu; Kobayashi Takaaki
XENOTRANSPLANTATION, Sep. 2013, Reviewed, No invitation
20(5), 317, 10.1111/xen.12060_10

Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.
Kenta Iwasaki; Paul D Ray; Bo-Wen Huang; Kensuke Sakamoto; Takaaki Kobayashi; Yoshiaki Tsuji
Biochemistry, Jul. 2013, Reviewed, No invitation
52(30), 5075, 83, 10.1021/bi400399f

Phosphorylation of 4E-BP1 predicts sensitivity to everolimus in gastric cancer cells.
Tetsuo Nishi; Kenta Iwasaki; Norifumi Ohashi; Chie Tanaka; Daisuke Kobayashi; Goro Nakayama; Masahiko Koike; Michitaka Fujiwara; Takaaki Kobayashi; Yasuhiro Kodera
Cancer letters, May 2013, Reviewed, No invitation
331(2), 220, 9, 10.1016/j.canlet.2013.01.004

Production of cloned pigs expressing human thrombomodulin in endothelial cells
Satoko Yazaki; Masaki Iwamoto; Akira Onishi; Yuko Miwa; Michiko Hashimoto; Takatsugu Oishi; Shunichi Suzuki; Dai-Ichiro Fuchimoto; Shoichiro Sembon; Tadashi Furusawa; DaGe Liu; Takaharu Nagasaka; Takafumi Kuzuya; Haruko Ogawa; Koji Yamamoto; Kenta Iwasaki; Masataka Haneda; Shoichi Maruyama; Takaaki Kobayashi
Xenotransplantation, Mar. 2012, Reviewed, No invitation
19(2), 82, 91, 10.1111/j.1399-3089.2012.00696.x

Comparative study on signal transduction in endothelial cells after anti-a/b and human leukocyte antigen antibody reaction: implication of accommodation.
Kenta Iwasaki; Yuko Miwa; Haruko Ogawa; Satoko Yazaki; Masaki Iwamoto; Tadashi Furusawa; Akira Onishi; Takafumi Kuzuya; Masataka Haneda; Yoshihiko Watarai; Kazuharu Uchida; Takaaki Kobayashi
Transplantation, Feb. 2012, Reviewed, No invitation
93(4), 390, 7, 10.1097/TP.0b013e3182424df3

Adipose-derived stromal cells cultured in a low-serum medium, but not bone marrow-derived stromal cells, impede xenoantibody production
Yosuke Saka; Kazuhiro Furuhashi; Takayuki Katsuno; Hangsoo Kim; Takenori Ozaki; Kenta Iwasaki; Masataka Haneda; Waichi Sato; Naotake Tsuboi; Yasuhiko Ito; Seiichi Matsuo; Takaaki Kobayashi; Shoichi Maruyama
XENOTRANSPLANTATION, May 2011, Reviewed, No invitation
18(3), 196, 208, 10.1111/j.1399-3089.2011.00640.x

Clinical significance of regulatory T-cell-related gene expression in peripheral blood after renal transplantation.
Hayato Iwase; Takaaki Kobayashi; Yasuhiro Kodera; Yuko Miwa; Takafumi Kuzuya; Kenta Iwasaki; Masataka Haneda; Akio Katayama; Asami Takeda; Kunio Morozumi; Yoshihiko Watarai; Kazuharu Uchida; Akimasa Nakao
Transplantation, Jan. 2011, Reviewed, No invitation
91(2), 191, 8, 10.1097/TP.0b013e3181ffbab4

Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.
Kiros Hailemariam; Kenta Iwasaki; Bo-Wen Huang; Kensuke Sakamoto; Yoshiaki Tsuji
Journal of cell science, Nov. 2010, Reviewed, No invitation
123(Pt 22), 3863, 71, 10.1242/jcs.073627

Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.
Kensuke Sakamoto; Bo-Wen Huang; Kenta Iwasaki; Kiros Hailemariam; Jun Ninomiya-Tsuji; Yoshiaki Tsuji
Molecular biology of the cell, Aug. 2010, Reviewed, No invitation
21(16), 2966, 74, 10.1091/mbc.E10-01-0015

Significance of HLA class I antibody-induced antioxidant gene expression for endothelial cell protection against complement attack.
Kenta Iwasaki; Yuko Miwa; Masataka Haneda; Kazuharu Uchida; Akimasa Nakao; Takaaki Kobayashi
Biochemical and biophysical research communications, Jan. 2010, Reviewed, No invitation
391(2), 1210, 5, 10.1016/j.bbrc.2009.12.042

Potential value of human thrombomodulin and DAF expression for coagulation control in pig-to-human xenotransplantation
Yuko Miwa; Koji Yamamoto; Akira Onishi; Masaki Iwamoto; Satoko Yazaki; Masataka Haneda; Kenta Iwasaki; Dage Liu; Haruko Ogawa; Takaharu Nagasaka; Kazuharu Uchida; Akimasa Nakao; Kenji Kadomatsu; Takaaki Kobayashi
Xenotransplantation, Jan. 2010, Reviewed, No invitation
17(1), 26, 37, 10.1111/j.1399-3089.2009.00555.x

Pretransplant pharmacodynamic analysis of immunosuppressive agents using CFSE-based T-cell proliferation assay
Y. Kurata; M. Kato; T. Kuzuya; Y. Miwa; K. Iwasaki; M. Haneda; K. Amioka; Y. Watarai; K. Uchida; A. Nakao; T. Kobayashi
Clinical Pharmacology and Therapeutics, Sep. 2009, Not reviewed, No invitation
86(3), 285, 289, 10.1038/clpt.2009.61

Stimulation index for PCNA mRNA in peripheral blood as immune function monitoring after renal transplantation.
Misao Niwa; Yuko Miwa; Takafumi Kuzuya; Kenta Iwasaki; Masataka Haneda; Tsuneo Ueki; Akio Katayama; Takahisa Hiramitsu; Norihiko Goto; Takaharu Nagasaka; Yoshihiko Watarai; Kazuharu Uchida; Akimasa Nakao; Takaaki Kobayashi
Transplantation, May 2009, Reviewed, No invitation
87(9), 1411, 4, 10.1097/TP.0b013e3181a277bb

Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications.
Kensuke Sakamoto; Kenta Iwasaki; Hiroyuki Sugiyama; Yoshiaki Tsuji
Molecular biology of the cell, Mar. 2009, Reviewed, No invitation
20(6), 1606, 17, 10.1091/mbc.E08-07-0762

Intracellular iron transport and storage: from molecular mechanisms to health implications.
Elizabeth L MacKenzie; Kenta Iwasaki; Yoshiaki Tsuji
Antioxidants & redox signaling, Jun. 2008, Reviewed, No invitation
10(6), 997, 1030, 10.1089/ars.2007.1893

PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element.
Kenta Iwasaki; Kiros Hailemariam; Yoshiaki Tsuji
The Journal of biological chemistry, Aug. 2007, Reviewed, No invitation
282(31), 22335, 43, 10.1074/jbc.M701477200

Hemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cells.
Kenta Iwasaki; Elizabeth L Mackenzie; Kiros Hailemariam; Kensuke Sakamoto; Yoshiaki Tsuji
Molecular and cellular biology, Apr. 2006, Reviewed, No invitation
26(7), 2845, 56

Interactions of a lysozyme-monomethoxypolyethylene glycol conjugate with lipopolysaccharides and lipid bilayers and effects of conjugate on gram-negative bacteria.
Yuichi Nodake; Kenta Iwasaki; Nobuyuki Yamasaki
Bioscience, biotechnology, and biochemistry, Sep. 2002, Reviewed, No invitation
66(9), 1848, 52, 10.1271/bbb.66.1848

Requirement for C-terminal extension to the RNA binding domain for efficient RNA binding by ribosomal protein L2.
Takeshi Hayashi; Maino Tahara; Kenta Iwasaki; Yoshiaki Kouzuma; Makoto Kimura
Bioscience, biotechnology, and biochemistry, Mar. 2002, Reviewed, No invitation
66(3), 682, 4, 10.1271/bbb.66.682

On the interaction of ribosomal protein L5 with 5S rRNA.
Kenta Iwasaki; Shingo Kikukawa; Shunsuke Kawamura; Yoshiaki Kouzuma; Isao Tanaka; Makoto Kimura
Bioscience, biotechnology, and biochemistry, Jan. 2002, Reviewed, No invitation
66(1), 103, 9, 10.1271/bbb.66.103

Ribosomal protein L5 has a highly twisted concave surface and flexible arms responsible for rRNA binding
T. Nakashima; M. Yao; S. Kawamura; K. Iwasaki; M. Kimura; I. Tanaka
RNA, 2001, Not reviewed, No invitation
7(5), 692, 701, 10.1017/S1355838201002345

mTORの免疫機能制御
日本小児腎不全学会雑誌, Jul. 2022

内皮細胞HLA-class II DRとアロ応答するCD4 T細胞は、anti-A/B抗体接着により抑制される
岩﨑 研太
日本組織適合性学会誌, 2018, Not reviewed

内皮細胞HLAの発現抑制シグナルの同定と薬剤探索（臓器保存生物医学会学術奨励賞報告）
岩﨑 研太
Organ Biology Vol.25, 2018, Not reviewed

異種移植と免疫順応
Organ Biology 23(2) 158-161, 2016

免疫モニタリング
岩﨑 研太
日本臨床腎移植学会50周年記念誌, 2016, Not reviewed

免疫順応
岩﨑 研太
病理と臨床, 2015, Not reviewed

内皮細胞における免疫順応促進シグナル伝達の知見から得られる薬剤選択
岩﨑 研太
ABO血液型不適合移植の新戦略―2013―（日本医学館）, 2013, Not reviewed

異種免疫応答を解決するための 遺伝子導入と免疫療法について
岩﨑研太
第49回日本臓器保存生物医学会学術集会 シンポジウム, Oct. 2023, Invited
Nominated symposium

アロ免疫を基盤としたDSA産生評価とワクチンアジュバンド研究
岩﨑研太
沖縄臓器移植セミナー2023 特別講演, Mar. 2023, Invited

アロ応答における免疫抑制剤の作用機序から得られる知見とXenotransplantation
岩﨑研太
第25回異種移植研究会モーニングセミナー 特別講演, Feb. 2023, Invited
Nominated symposium

In silico と in vitro 解析における de novo DSA リスク評価
岩﨑研太
第48回日本臓器保存生物医学会学術集会 プロジェクト小委員会企画プログラム①：臓器-ホストレスポンス研究プロジェクト小委員会, Nov. 2022, Invited

In silico DSA産生予測と、樹状細胞を用いたindirect alloresponse検出系による感作把握
岩﨑研太
第58回日本移植学会総会 臓器移植後拒絶反応の克服シンポジウム, Oct. 2022
Nominated symposium

mTORによる免疫機能制御
岩﨑研太
第42回日本小児腎不全学会学術集会 スポンサードセミナー, Dec. 2021, Invited

Indirect allorecognition評価法の確立とモニタリングへの応用
岩﨑研太
第57回日本移植学会総会 臓器横断的シンポジウム, Sep. 2021, Invited

CD40/共刺激経路を含むアロ免疫機構の基礎知識
岩﨑研太
勉強会 ※Web開催 講師, Feb. 2021, Invited
Public discourse

アロ応答における免疫抑制剤と副次的効果
岩﨑研太
第2回信濃町臓器移植ミーティング 特別講演, Dec. 2020, Invited
Public discourse

長期生着時代の免疫抑制剤の課題と展望
岩﨑 研太
第63回大阪腎移植病理組織研究会 特別講演, Dec. 2019, Invited
Invited oral presentation, Domestic conference

移植免疫におけるmTOR
岩﨑 研太
第55回日本移植学会総会 ランチョンセミナー, Oct. 2019, Invited

抗体関連型拒絶反応抵抗性獲得メカニズムに関する研究
岩﨑 研太
第55回日本移植学会総会 臓器横断シンポジウム, Oct. 2019, Invited

免疫担当細胞と内皮細胞におけるmTOR阻害薬の効果とその可能性
岩﨑 研太
第38回日本心臓移植研究会学術集会 スイーツセミナー, Oct. 2019, Invited

mTORによるサイトカイン制御
岩﨑 研太
第28回組織適合性学会 ランチョンセミナー, Sep. 2019, Invited

抗体関連型拒絶反応の内皮傷害の分子メカニズム：補体依存性・非依存性
岩﨑 研太
第22回移植腎病理研究会 教育講演, Jul. 2018, No invitation

腎移植患者末梢Tfh/Treg解析と免疫抑制剤の影響
岩﨑 研太
第53回日本移植学会総会 臓器横断シンポジウム, Sep. 2017, Invited

内皮細胞HLA発現を制御可能な薬剤
岩﨑 研太
第53回日本移植学会総会 ランチョンセミナー, Sep. 2017, Invited

血清中miRNA解析による抗体関連型拒絶反応診断の可能性
岩﨑 研太
第53回日本移植学会総会 臓器横断シンポジウム, Sep. 2017, No invitation

B細胞制御に関する最近の知見
岩﨑 研太
Renal Transplant Forum 特別講演, Nov. 2016, Invited

mTOR-i mode of action as immunosuppressant
岩﨑 研太
第1回Kidney TransplantAsian Summit 特別講演, Jun. 2016, Invited

mTOR阻害薬・カルシニューリン阻害薬の免疫応答変化と個体間差
岩﨑 研太
第32回腎移植・血管外科学会研究会 シンポジウム, May 2016, Invited

mTOR阻害による抗体産制と抗体抗原反応に与える効果
岩﨑 研太
第49回日本臨床腎移植学会 ランチョンセミナー, Mar. 2016, Invited

抗体産生と抗原発現ーmTOR阻害剤の可能性ー
岩﨑 研太
第51回大阪腎移植病理組織研究会 特別講演, Dec. 2015, Invited

ERKとmTORを標的としたNon-Gal・HLA・ABO抗体関連型拒絶反応制御
岩﨑 研太
第42回日本臓器保存生物医学会 シンポジウム, Nov. 2015, No invitation

抗体産生と抗原発現ーmTOR阻害剤の可能性ー
岩﨑 研太
第51回日本移植学会総会 シンポジウム, Oct. 2015, No invitation

エベロリムス（EVR）の臨床使用経験と基礎研究～内皮細胞と抗体産生～
岩﨑 研太
第28回神奈川腎移植を勉強する会 特別講演, Jun. 2015, Invited

ヒト化マウスを用いたドナー特異的抗体産生核酸の同定・機能解明と診断治療への応用
基盤研究(C)
愛知医科大学
Apr. 2024 - Mar. 2027
野田貴幸; 岩崎研太; 小林孝彰, 野田貴幸; 岩崎研太; 小林孝彰, 日本学術振興会, 日本学術振興会, Coinvestigator

ヒトnaive B細胞から抗原特異的抗体産生細胞をin vitroで作成する画期的手法の開発
挑戦的研究(萌芽)
愛知医科大学
Jun. 2024 - Mar. 2026
岩﨑研太; 山崎達也; 高村(赤司)祥子, 小林孝彰, 岩﨑研太; 山崎達也; 高村(赤司)祥子, 小林孝彰, 日本学術振興会, 日本学術振興会, Principal investigator

ヒト乳歯歯髄幹細胞を用いた膵島オルガノイドによる画期的膵島移植プロトコールの開発
基盤研究(C)
愛知医科大学
Apr. 2023 - Mar. 2026
石山宏平; 岩﨑研太; 恒川新, 石山宏平; 岩﨑研太; 恒川新, 日本学術振興会, 日本学術振興会, Coinvestigator

抗体関連型拒絶反応におけるimmunogenetic peptideの機序解明
Jul. 2024 - Mar. 2025
河田賢; 岩﨑研太; 雫真人; 安次嶺聡; 石山宏平; 小林孝彰, 河田賢; 岩﨑研太; 雫真人; 安次嶺聡; 石山宏平; 小林孝彰, Coinvestigator

Single cell解析によるヒト間葉系幹細胞の新規免疫抑制メカニズムの解明
Jul. 2024 - Mar. 2025
石山宏平; 加藤誠; 三輪祐子; 清瀬俊樹; 岩﨑研太, 石山宏平; 加藤誠; 三輪祐子; 清瀬俊樹; 岩﨑研太, Coinvestigator

機械学習による多機能性B細胞の同定とその臨床応用
Jul. 2024 - Mar. 2025
岩﨑研太、安次嶺聡、山崎達也、河田賢, 岩﨑研太、安次嶺聡、山崎達也、河田賢, Principal investigator

IVIgによる獲得免疫増強機構の解明
愛知医科大学学内研究ユニット創出支援事業
Jun. 2023 - Mar. 2024
岩﨑研太; 雫真人; 松岡直也, 岩﨑研太; 雫真人; 松岡直也, Principal investigator

Single cell RNA sequence解析とT細胞受容体レパトア解析を組み合わせた新たな臓器移植後のDSA産生予測モデルの開発
JST basic research grants
Apr. 2023 - Mar. 2024
雫真人; 岩﨑研太, 雫真人; 岩﨑研太, Coinvestigator

小児臓器移植後の持続 EBV-DNA 血症に対するアロ感染免疫応答の基盤研究と臨床応用
Apr. 2023 - Mar. 2024
雫真人; 岩﨑研太, 雫真人; 岩﨑研太, Coinvestigator

ヒト化マウスによるドナー特異的抗体産生免疫プロファイリングの解明と個別化医療
基盤研究(C)
愛知医科大学
Apr. 2021 - Mar. 2024
野田貴幸; 岩﨑研太; 小林孝彰, 野田貴幸; 岩﨑研太; 小林孝彰, 日本学術振興会, 日本学術振興会, Coinvestigator

非翻訳RNAに着目したCNI腎症早期発見システムの構築
基盤研究(C)
愛知医科大学
Apr. 2021 - Mar. 2024
畔柳 佳幸; 岩崎 研太; 小林 孝彰; 三輪 祐子, 畔柳 佳幸; 岩崎 研太; 小林 孝彰; 三輪 祐子, 日本学術振興会, 日本学術振興会, Coinvestigator

Identification of Indirect Alloreactive T-Cells and Application to Monitoring of anti-Donor Antibody Sensing
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
Apr. 2021 - Mar. 2023
岩﨑研太, 岩﨑研太, 日本学術振興会, Japan Society for the Promotion of Science, Principal investigator

Identification and control of follicular helper T cell clonotype related to donor specific HLA antibody production
Grant-in-Aid for Challenging Research (Pioneering)
Aichi Medical University
Jul. 2020 - Mar. 2023
小林孝彰; 岩﨑研太; 三輪祐子; 安次嶺聡; 西村泰治; 岸裕幸; 一戸辰夫, 小林孝彰; 岩﨑研太; 三輪祐子; 安次嶺聡; 西村泰治; 岸裕幸; 一戸辰夫, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

From treatment to prevention: development of innovative immune regulation based on epitope/paratope analysis
Grant-in-Aid for Scientific Research (B)
Aichi Medical University
Apr. 2020 - Mar. 2023
小林孝彰; 岩﨑研太; 三輪祐子; 野田貴幸; 石山宏平; 勝野敬之, 小林孝彰; 岩﨑研太; 三輪祐子; 野田貴幸; 石山宏平; 勝野敬之, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

RP105を介した抗原特異的抗体産生ヒトB細胞取得とその活性化メカニズムの解明
2022 - 2023
岩﨑研太; 山崎達也; 安次嶺聡; 奥村真衣, 岩﨑研太; 山崎達也; 安次嶺聡; 奥村真衣

anti-RP105による効率的な抗原特異的抗体産生ヒトB細胞取得
Aug. 2021 - Aug. 2022
岩﨑研太; 山崎達也; 安次嶺聡; 奥村真衣, 岩﨑研太; 山崎達也; 安次嶺聡; 奥村真衣, Principal investigator

Improvement of BK virus monitoring system in renal transplantation with the aim of graft long-term survival.
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
Apr. 2019 - Mar. 2022
三輪祐子; 岩﨑研太; 齋藤尚二; 小林孝彰, YUKO MIWA, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

de novo DSA産生に影響を及ぼす, レシピエントHLA class II・ドナーpeptideの複合体
Apr. 2020 - Mar. 2021
松岡直也、岩﨑研太, 松岡直也、岩﨑研太, Coinvestigator

A multifaceted approach to HLA antibody-producing B cells for donor-specific antibody (DSA) regulation
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
Apr. 2018 - Mar. 2021
野田貴幸; 岩﨑研太; 小林孝彰, NODA Takayuki, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

慢性腎不全・移植腎におけるAutophagy制御と腎保護効果の検証
Apr. 2019 - Mar. 2020
松岡直也; 岩﨑研太, 松岡直也; 岩﨑研太, Coinvestigator

de novo DS産生制御のためのIndirect Alloresponseに特化した先制的免疫モニタリング
JST basic research grants
Apr. 2019 - Mar. 2020
前仲亮宏; 岩﨑研太, 前仲亮宏; 岩﨑研太, Coinvestigator

長期生着を目指したIndividual immune monitoringの構築
基盤研究(C)
愛知医科大学
Apr. 2019 - Mar. 2020
松岡裕; 岩﨑研太; 小林孝彰; 三輪祐子, 松岡裕; 岩﨑研太; 小林孝彰; 三輪祐子, 日本学術振興会, 日本学術振興会, Coinvestigator

Autophagy活性化による腎臓病克服のための基礎研究
Apr. 2019 - Mar. 2020
岩﨑研太、松岡直也, 岩﨑研太、松岡直也, 愛知医科大学, 愛知医科大学, Principal investigator

ドナー特異的抗体産生細胞の同定と、その制御法の開発
Apr. 2019 - Mar. 2020
岩﨑研太, 岩﨑研太, 財団法人那古野医学振興会, 財団法人那古野医学振興会, Principal investigator

Introduction of precision medicine in renal transplantation: attempt to overcome HLA mismatch by TCR/BCR control
Grant-in-Aid for Challenging Research (Exploratory)
Aichi Medical University
Jun. 2018 - Mar. 2020
小林孝彰; 岩﨑研太; 三輪 祐子, Kobayashi Takaaki, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

ドナー特異的アロ応答性T細胞の同定とクローン追跡による免疫反応の把握
Apr. 2019 - 2020
岩﨑研太, 岩﨑研太, タケダ・リサーチサポート, タケダ・リサーチサポート, Principal investigator

臓器移植を革新する免疫プロファイリングによる個別化医療の開発
Apr. 2019
代表; 大段秀樹; 分担; 岩﨑研太, 代表; 大段秀樹; 分担; 岩﨑研太, Coinvestigator

Introduction of preventive and preemptive medicine against chronic antibody-mediated rejection for long-term graft survival
Grant-in-Aid for Scientific Research (B)
Aichi Medical University
Apr. 2016 - Mar. 2019
小林孝彰; 岩﨑研太; 三輪祐子; 丸山彰一, KOBAYASHI TAKAAKi; NODA Takayuki; MAENAKA AKIHIRO; NOBATA Hironobu; OKADA Manabu; YAMAMOTO Takayuki; TOMOSUGI Toshihide; OKUMURA Mai; INOKO Hidetoshi, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

Development of immunological risk-benefit analysis and antibody treatment in ABO blood group incompatible kidney transplantation
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
Apr. 2016 - Mar. 2019
三輪祐子; 岩﨑研太; 小林孝彰, MIWA YUKO, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

HLA / A / B antibodies and endothelial cell responses that generate T cell subpopulation a new innovation in antibody-positive transplantation
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
2017 - 2019
岩﨑研太, Iwasaki Kenta, 文部科学省科学研究費, Japan Society for the Promotion of Science, Principal investigator

Diversity analysis of antibody function and development of strategy to overcome antibody-mediate rejection: Establishment of pig model for ABO/HLA-incompatibility
Grant-in-Aid for Challenging Exploratory Research
Aichi Medical University
Apr. 2015 - Mar. 2017
小林孝彰; 岩﨑研太; 羽根田正隆; 大西彰; 三輪祐子, KOBAYASHI Takaaki; FUCHIMOTO Daiichiro; SUZUKI Shunichi; YAMAMOTO Takayuki; OKADA Manabu; TAKEDA Asami; HIRAMITSU Takahisa; KITAGAWA Hitoshi; IMAEDA Noriaki; HANEDA Masataka; HORIMI Kosei; MATSUOKA Yutaka; MAENAKA Akihiro, 日本学術振興会, Japan Society for the Promotion of Science

内皮細胞 HLA の発現抑制シグナルの同定と薬剤探索
2016 - 2017
岩﨑研太, 岩﨑研太, 日本臓器保存生物医学会, 日本臓器保存生物医学会, Principal investigator

抗体関連型傷害抵抗を誘導するシグナル伝達
Apr. 2015 - Mar. 2016
岩﨑研太, 岩﨑研太, 財団法人那古野医学振興会, 財団法人那古野医学振興会, Principal investigator

Comprehensive study on control of chronic antibody-mediated rejection after renal transplantation
Grant-in-Aid for Scientific Research (B)
Apr. 2013 - Mar. 2016
小林孝彰; 岩﨑研太; 三輪祐子; 丸山彰一; 大西彰; 小川晴子; 羽根田政隆; 葛谷孝文, KOBAYASHI Takaaki; IWASAKI Kenta; MIWA Yuko; MARUYAMA Shoichi; ONISHI Akira; OGAWA Haruko; HANEDA Masataka; KUZUYA Takafumi; MATSUDA Yoshiko; YAMAMOTO Takayuki; HIRAMITSU Takahisa; Ashimine Satoshi; INANAGA Yukiko; HORIMI Kosei; KITAHATA Nana; LIU DaGe; KUSHIHARA Hideyuki; KURATA Yoko; OKADA Manabu; MATSUOKA Yutaka, 日本学術振興会, Japan Society for the Promotion of Science

Analysis of pleiotropic property of thrombomodulin and development of therapeutic strategy using thrombomodulin in transplantation
Grant-in-Aid for Scientific Research (C)
Apr. 2013 - Mar. 2016
三輪祐子; 岩﨑研太; 小林孝彰; 大西彰, MIWA YUKO; KOBAYASHI TAKAAKI; IWASAKI KENTA; ONISHI AKIRA, 日本学術振興会, Japan Society for the Promotion of Science

The prevention against chronic antibody mediated rejection on graft endothelial
Grant-in-Aid for Scientific Research (C)
2014 - 2016
岩﨑研太, Iwasaki Kenta, 文部科学省科学研究費, Japan Society for the Promotion of Science, Principal investigator

Practical strategies for treatment of antibody mediated chronic rejection with inherent immune system
Grant-in-Aid for Scientific Research (C)
Nagoya University
Apr. 2012 - Mar. 2015
羽根田正隆; 岩﨑研太; 小林孝彰; 三輪祐子; 松田佳子, HANEDA MASATAKA; KOBAYASHI Takaaki; IWASAKI Kenta; MIWA Yuko; MASTUDA Yoshiko, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

抗体関連型拒絶反応抵抗性獲得を可能にするシグナル伝達経路の同定とそ の診断
2014 - 2015
岩﨑研太, 岩﨑研太, 愛知県腎臓財団, 愛知県腎臓財団, Principal investigator

Development of in vitro culture for peripheral B cell differentiation into plasma cell
Grant-in-Aid for Challenging Exploratory Research
Nagoya University
Apr. 2012 - Mar. 2014
小林孝彰; 岩﨑研太; 羽根田政隆; 三輪祐子; 葛谷孝文, KOBAYASHI Takaaki; HANEDA Masataka; IWASAKI Kenta; MIWA Yuko; KUZUYA Takafumi, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

The identification of HLA class II DR associated molecules contributing to Accommodation
Grant-in-Aid for Young Scientists (B)
Nagoya University
2012 - 2013
岩﨑研太, IWASAKI Kenta, 文部科学省科学研究費, Japan Society for the Promotion of Science, Principal investigator

Development of pre-transplant assessments that predict AntibodyMediated Rejection(AMR)
Grant-in-Aid for Scientific Research (C)
Nagoya University
2010 - 2012
三輪祐子; 岩﨑研太; 小林孝彰; 羽根田正隆, MIWA Yuko; KOBAYASHI Takaaki; HANEDA Masataka; IWASAKI Kenta, 日本学術振興会, Japan Society for the Promotion of Science

薬力学および免疫機能モニタリングによる臓器移植患者の包括的支援体制の構築
基盤研究(C)
名古屋大学
2011 - 2011
葛谷孝文; 小林孝彰; 羽根田正隆; 岩﨑研太; 田中友加, 葛谷孝文; 小林孝彰; 羽根田正隆; 岩﨑研太; 田中友加, 日本学術振興会, 日本学術振興会

The study on signal transduction to reduce the risk of antibody mediated chronic rejection
Grant-in-Aid for Young Scientists (B)
Nagoya University
2010 - 2011
岩﨑研太, IWASAKI Kenta, 文部科学省科学研究費, Japan Society for the Promotion of Science, Principal investigator

Establishment of a new evaluation method of post-transplant immune tolerance by donor-specific regulatory T cell analysis
Grant-in-Aid for Scientific Research (C)
Nagoya University
2009 - 2011
羽根田正隆; 岩﨑研太; 小林 孝彰, HANEDA Masataka; KOBAYASHI Takaaki; IWASAKI Kenta, 日本学術振興会, Japan Society for the Promotion of Science

Dynamic analysis of antigen, antibody, complement, inflammation and coagulation related to rejection, accommodation and tolerance
Grant-in-Aid for Scientific Research (B)
Nagoya University
2008 - 2010
小林孝彰; 山本晃士; 竹田伸; 丸山彰一; 羽根田正隆; 岸田聡; 岩崎研太; 大西彰; 小川晴子, KOBAYASHI Takaaki; YAMAMOTO Koji; TAKEDA Shin; MARUYAMA Shoichi; HANEDA Masataka; KISHIDA Satoshi; IWASAKI Kenta; ONISHI Akira; OGAWA Haruko, 日本学術振興会, Japan Society for the Promotion of Science

Individualization of Immunosuppressive Therapy Using Pharmacodynamics, Immunology and Molecular Biology
Grant-in-Aid for Scientific Research (C)
Nagoya University
2008 - 2010
葛谷孝文; 小林孝彰; 羽根田正隆; 小寺泰弘; 岩﨑研太, KUZUYA Takafumi; KOBAYASHI Takaaki; HANEDA Masataka; KODERA Yasuhiro; IWASAKI Kenta, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator

The Study of the signaling pathway on the endothelial cells after antibody-antigen binding.
Grant-in-Aid for Young Scientists (Start-up)
Nagoya University
2008 - 2009
岩﨑研太, IWASAKI Kenta, 文部科学省科学研究費, Japan Society for the Promotion of Science, Principal investigator