Medical education

Stress

Sympathetic nervous system

Neuroendocrinology

2017 - Present
日本自律神経学会, 評議員

2016 - Present
日本薬理学会, 学術評議員

Yokukansan, a Traditional Japanese Medicine, Suppresses Stress-Induced Sympathetic Activation via Central Responses in Rats
Naoko Yamaguchi; Kenta Maruyama; Shoshiro Okada
Natural Product Communications, Nov. 2023, Reviewed
Lead, 10.1177/1934578X231203085

Investigation of patients’ mood on their distance from the pharmacist during medication instruction.
Gocho S; Miyagi Y; Yamaguchi N; Nakayama C; Miyachi Y; Okada S; Oshima T
Pharmacology & Pharmacy, May 2023, Reviewed
14, 145, 155, 10.4236/pp.2023.145011

Predicting the effect of pharmacist's communication with patients: medical communication analysis using facial responses.
Miyagi Y; Gocho S; Yamaguchi N; Miyachi Y; Nakayama C; Okada S; Oshima T
J. Pharm. Health Serv. Res., May 2023, Reviewed
14, 221, 227, 10.1093/jphsr/rmad029

Glucose infusion suppresses acute restraint stress-induced peripheral and central sympathetic responses in rats
Naoko Yamaguchi; Yoshihiko Kakinuma; Tomiko Yakura; Munekazu Naito; Shoshiro Okada
Autonomic Neuroscience, May 2022, Reviewed
Lead, 239, 102957, 102957, 10.1016/j.autneu.2022.102957

Acute intracerebroventricular injection of chemerin-9 increases systemic blood pressure through activating sympathetic nerves via CMKLR1 in brain
Atsunori Yamamoto; Kengo Matsumoto; Kiko Hori; Satoshi Kameshima; Naoko Yamaguchi; Shoshiro Okada; Muneyoshi Okada; Hideyuki Yamawaki
Pflugers Archiv European Journal of Physiology, Jun. 2020
472(6), 673, 681, 10.1007/s00424-020-02391-4

Thromboxane A2 in the paraventricular hypothalamic nucleus mediates glucoprivation-induced adrenomedullary outflow
Masahiko Tachi; Naoko Yamaguchi; Shoshiro Okada
European Journal of Pharmacology, May 2020, Reviewed, No invitation
Lead, 875, 173034, 173034, 10.1016/j.ejphar.2020.173034

Clostridium butyricum Modulates the Microbiome to Protect Intestinal Barrier Function in Mice with Antibiotic-Induced Dysbiosis.
Mao Hagihara; Yasutoshi Kuroki; Tadashi Ariyoshi; Seiya Higashi; Kazuo Fukuda; Rieko Yamashita; Asami Matsumoto; Takeshi Mori; Kaoru Mimura; Naoko Yamaguchi; Shoshiro Okada; Tsunemasa Nonogaki; Tadashi Ogawa; Kenta Iwasaki; Susumu Tomono; Nobuhiro Asai; Yusuke Koizumi; Kentaro Oka; Yuka Yamagishi; Motomichi Takahashi; Hiroshige Mikamo
iScience, Jan. 2020, Reviewed, No invitation
23(1), 100772, 100772, 10.1016/j.isci.2019.100772

Prostaglandin E2 receptor EP3 subtype in the paraventricular hypothalamic nucleus mediates corticotropin-releasing factor-induced elevation of plasma noradrenaline levels in rats
Naoko Yamaguchi
European Journal of Pharmacology, Nov. 2019, Reviewed, No invitation
Lead, 863, 172693, 10.1016/j.ejphar.2019.172693

ストレスによる血中カテコールアミン遊離・分泌の中枢性調節
岡田尚志郎; 山口奈緒子
内分泌・糖尿病・代謝内科, Oct. 2019, Reviewed, Invited
Last, 49(4), 322, 327

GABAB receptors in the hypothalamic paraventricular nucleus mediate β-adrenoceptor-induced elevations of plasma noradrenaline in rats
Naoko Yamaguchi
European Journal of Pharmacology, Apr. 2019, Reviewed, No invitation
Lead, 848, 88, 95, 10.1016/j.ejphar.2019.01.029

The role of estrogen receptor β in the dorsal raphe nucleus on the expression of female sexual behavior in C57BL/6J mice
Kazuhiro Sano; Chihiro Morimoto; Mariko Nataka; Sergei Musatov; Mumeko C. Tsuda; Naoko Yamaguchi; Toshiro Sakamoto; Sonoko Ogawa
Frontiers in Endocrinology, May 2018, Reviewed, No invitation
9(MAY), 243, 10.3389/fendo.2018.00243

Differential roles of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor-induced sympathetic activation in rats
YAMAGUCHI Naoko
自律神経, 2018, Reviewed, Invited
Lead, 55, 295, 300

Possible role of adrenoceptors in the hypothalamic paraventricular nucleus in corticotropin-releasing factor -induced sympatho-adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, Mar. 2017, Reviewed, No invitation
Last, 203, 74, 80, 10.1016/j.autneu.2017.01.008

Effects of aging on stress-related responses of serotonergic neurons in the dorsal raphe nucleus of male rats
Naoko Yamaguchi; Noriaki Nakajima; Shoshiro Okada; Kazunari Yuri
Neurobiology of Stress, Jun. 2016, Reviewed, No invitation
Lead, 3, 43, 51, 10.1016/j.ynstr.2016.01.002

Effects of prepubertal or adult site-specific knockdown of estrogen receptor β in the medial preoptic area and medial amygdala on social behaviors in male mice
Mariko Nakata; Kazuhiro Sano; Sergei Musatov; Naoko Yamaguchi; Toshiro Sakamoto; Sonoko Ogawa
eNeuro, 2016, Reviewed, No invitation
3(2), 579, 588, 10.1523/ENEURO.0155-15.2016

Centrally administered isoproterenol induces sympathetic outflow via brain prostaglandin E-2-mediated mechanisms in rats
Kazuo Ando; Fumio Kondo; Naoko Yamaguchi; Masahiko Tachi; Minoru Fukayama; Kazuhiro Yoshikawa; Masahiko Gosho; Yoshihiro Fujiwara; Shoshiro Okada
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, May 2015, Reviewed, No invitation
189, 1, 7, 10.1016/j.autneu.2014.12.002

Modification of female and male social behaviors in estrogen receptor beta knockout mice by neonatal maternal separation
Mumeko C. Tsuda; Naoko Yamaguchi; Mariko Nakata; Sonoko Ogawa
FRONTIERS IN NEUROSCIENCE, Sep. 2014, Reviewed, No invitation
8, 274, 10.3389/fnins.2014.00274

Estrogen-dependent changes in estrogen receptor-beta mRNA expression in middle-aged female rat brain
Naoko Yamaguchi; Kazunari Yuri
BRAIN RESEARCH, Jan. 2014, Reviewed, No invitation
Lead, 1543, 49, 57, 10.1016/j.brainres.2013.11.010

Changes in Oestrogen Receptor-beta mRNA Expression in Male Rat Brain with Age
N. Yamaguchi; K. Yuri
JOURNAL OF NEUROENDOCRINOLOGY, Feb. 2012, Reviewed, No invitation
Lead, 24(2), 310, 318, 10.1111/j.1365-2826.2011.02231.x

Early life stress disrupts peripubertal development of aggression in male mice
Mumeko C. Tsuda; Naoko Yamaguchi; Sonoko Ogawa
NEUROREPORT, Apr. 2011, Reviewed, No invitation
22(6), 259, 263, 10.1097/WNR.0b013e328344495a

CYCLOOXYGENASE AND NITRIC OXIDE SYNTHASE IN THE PRESYMPATHETIC NEURONS IN THE PARAVENTRICULAR HYPOTHALAMIC NUCLEUS ARE INVOLVED IN RESTRAINT STRESS-INDUCED SYMPATHETIC ACTIVATION IN RATS
N. Yamaguchi; S. Ogawa; S. Okada
NEUROSCIENCE, Oct. 2010, Reviewed, No invitation
Lead, 170(3), 773, 781, 10.1016/j.neuroscience.2010.07.051

alpha 1-Adrenoceptor activation is involved in the central N-methyl-D-aspartate-induced adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi
EUROPEAN JOURNAL OF PHARMACOLOGY, Aug. 2010, Reviewed, No invitation
Last, 640(1-3), 55, 62, 10.1016/j.ejphar.2010.04.038

Organizational effects of pubertal testosterone on socio-sexual and emotional behaviors in male mice
Mariko Kobayashi; Misho Kashimura; Naoko Yamaguchi; Toshiro Sakamoto; Sonoko Ogawa
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation
68, E412, E412, 10.1016/j.neures.2010.07.1829

Cyclooxygenase-1 and-2 in spinally projecting neurons are involved in CRF-induced sympathetic activation
Naoko Yamaguchi; Shoshiro Okada
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, Dec. 2009, Reviewed, No invitation
Lead, 151(2), 82, 89, 10.1016/j.autneu.2009.06.009

Nitric oxide synthase isozymes in spinally projecting PVN neurons are involved in CRF-induced sympathetic activation
Naoko Yamaguchi; Shoshiro Okada; Daisuke Usui; Kunihiko Yokotani
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, Jun. 2009, Reviewed, No invitation
Lead, 148(1-2), 83, 89, 10.1016/j.autneu.2009.02.009

Central bombesin activates adrenal adrenaline- and noradrenaline-containing cells via brain thromboxane A(2) in rats
Daisuke Usui; Naoko Yamaguchi-Shima; Shoshiro Okada; Takahiro Shimizu; Hiroshi Wakiguchi; Kunihiko Yokotani
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, May 2009, Reviewed, No invitation
Corresponding, 147(1-2), 33, 37, 10.1016/j.autneu.2008.12.014

Selective activation of the sympathetic ganglia by centrally administered corticotropin-releasing factor in rats
Daisuke Usui; Naoko Yamaguchi-Shima; Shoshiro Okada; Takahiro Shimizu; Hiroshi Wakiguchi; Kunihiko Yokotani
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, Mar. 2009, Reviewed, No invitation
Corresponding, 146(1-2), 111, 114, 10.1016/j.autneu.2008.12.008

Role of brain prostanoids in glucagon-like peptide-1-induced central activation of sympatho-adrenomedullary outflow in rats
Junichi Arai; Shoshiro Okada; Naoko Yamaguchi-shima; Takahiro Shimizu; Tsuyoshi Sasaki; Mieko Yorimitsu; Hiroshi Wakiguchi; Kunihiko Yokotani
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Aug. 2008, Reviewed, No invitation
35(8), 965, 970, 10.1111/j.1440-1681.2008.04957.x

Role of brain nicotinic acetylcholine receptor in centrally administered corticotropin-releasing factor-induced elevation of plasma corticosterone in rats
Shoshiro Okada; Naoko Yamaguchi-Shima; Takahiro Shimizu; Junichi Arai; Lu Lianyi; Hiroshi Wakiguchi; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Jun. 2008, Reviewed, No invitation
587(1-3), 322, 329, 10.1016/j.ejphar.2008.03.005

Centrally administered N-methyl-D-aspartate evokes the adrenal secretion of noradrenaline and adrenaline by brain thromboxane A(2)-mediated mechanisms in rats
Shoshiro Okada; Naoko Yamaguchi-Shima; Takahiro Shimizu; Junichi Arai; Mieko Yorimitsu; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, May 2008, Reviewed, No invitation
586(1-3), 145, 150, 10.1016/j.ejphar.2008.02.069

Brain nuclear factor kappa B is involved in the corticotropin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi-Shima; Takahiro Shimizu; Junichi Arai; Mieko Yorirnitsu; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2008, Reviewed, No invitation
584(1), 207, 212, 10.1016/j.ejphar.2008.01.037

Role of brain adrenoceptors in the corticortopin-releasing factor-induced central activation of sympatho-adrenomedullary outflow in rats
Mieko Yorimitsu; Shoshiro Okada; Naoko Yamaguchi-Shima; Takahiro Shimizu; Junichi Arai; Kunihiko Yokotani
LIFE SCIENCES, Feb. 2008, Reviewed, No invitation
82(9-10), 487, 494, 10.1016/j.lfs.2007.12.006

Roles of brain phosphatidylinositol-specific phospholipase C and diacylglycerol lipase in centrally administered histamine-induced adrenomedullary outflow in rats
Takahiro Shimizu; Naoko Yamaguchi; Shoshiro Okada; Lianyi Lu; Tsuyoshi Sasaki; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Oct. 2007, Reviewed, No invitation
571(2-3), 138, 144, 10.1016/j.ejphar.2007.05.061

Age-related changes in the expression of ER-beta mRNA in the female rat brain
Naoko Yamaguchi-Shima; Kazunari Yuri
BRAIN RESEARCH, Jun. 2007, Reviewed, No invitation
Lead, 1155, 34, 41, 10.1016/j.brainres.2007.04.016

Adrenal adrenaline- and noradrenaline-containing cells and celiac sympathetic ganglia are differentially controlled by centrally administered corticotropin-releasing factor and arginine-vasopressin in rats
Naoko Yamaguchi-Shima; Shoshiro Okada; Takahiro Shimizu; Daisuke Usui; Kumiko Nakamura; Lianyi Lu; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Jun. 2007, Reviewed, No invitation
Lead, 564(1-3), 94, 102, 10.1016/j.ejphar.2007.02.021

Centrally administered histamine evokes the adrenal secretion of noradrenaline and adrenaline by brain cyclooxygenase-1 and thromboxane A(2)-mediated mechanisms in rats
Takahiro Shimizu; Shoshiro Okada; Naoko Yamaguchi; Tsuyoshi Sasaki; Lianyi Lu; Kunihiko Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Jul. 2006, Reviewed, No invitation
541(3), 152, 157, 10.1016/j.ejphar.2006.05.013

Brain phospholipase C/diacylglycerol lipase are involved in bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats
T Shimizu; S Okada; N Yamaguchi; J Arai; H Wakiguchi; K Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, May 2005, Reviewed, No invitation
514(2-3), 151, 158, 10.1016/j.cjphar.2005.03.033

Brain prostanoid TP receptor-mediated adrenal noradrenaline secretion and EP3 receptor-mediated sympathetic noradrenaline release in rats
K Yokotani; S Okada; K Nakamura; N Yamaguchi-Shima; T Shimizu; J Arai; H Wakiguchi; K Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Apr. 2005, Reviewed, No invitation
512(1), 29, 35, 10.1016/j.ejphar.2005.02.027

Role of K+ channels in M-2 muscarinic receptor-mediated inhibition of noradrenaline release from the rat stomach
K Nakamura; S Okada; N Yamaguchi; T Shimizu; K Yokotani; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, Nov. 2004, Reviewed, No invitation
96(3), 286, 292, 10.1254/jphs.FPJ04036X

Brain phospholipase C-diacylglycerol lipase pathway is involved in vasopressin-induced release of noradrenaline and adrenaline from adrenal medulla in rats
T Shimizu; S Okada; N Yamaguchi-Shima; K Yokotani
EUROPEAN JOURNAL OF PHARMACOLOGY, Sep. 2004, Reviewed, No invitation
499(1-2), 99, 105, 10.1016/j.ejphar.2004.07.087

Distribution of estrogen receptor β mRNA-containing cells in ovariectomized and estrogen-treated female rat brain
Naoko Shima; Yoshihide Yamaguchi; Kazunari Yuri
Anatomical Science International, Jun. 2003, Reviewed, No invitation
Lead, 78(2), 85, 97, 10.1046/j.0022-7722.2003.00042.x

2-デオキシグルコースの末梢投与はラット視床下部室傍核のノルアドレナリン遊離および血中カテコラミン値を増加させる 脳内プロスタグランジンの役割
舘 昌彦; 山口 奈緒子; 深山 実; 吉川 和宏; 近藤 文雄; 岡田 尚志郎
自律神経, Jun. 2016, Not reviewed, No invitation
53(2), 201, 201

2-デオキシグルコースの末梢投与はラット視床下部室傍核のノルアドレナリン遊離および血中カテコラミン値を増加させる 脳内プロスタグランジンの役割
舘 昌彦; 山口 奈緒子; 深山 実; 吉川 和宏; 近藤 文雄; 岡田 尚志郎
日本自律神経学会総会プログラム・抄録集, Oct. 2015, Not reviewed, No invitation
68回, 107, 107

Hormonal and environmental regulation of social behavior
Sonoko Ogawa; Mumeko C. Tsuda; Naoko Yamaguchi; Toshiro Sakamoto; Masaki Kakeyama
NEUROSCIENCE RESEARCH, 2011, Not reviewed, No invitation
71, E12, E13, 10.1016/j.neures.2011.07.047

Role of inflammatory mediators in acute restraint stress-induced elevation of plasma catecholamines in rats
Shoshiro Okada; Naoko Yamaguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, Not reviewed, No invitation
115, 283P, 283P

Role of oxytocin receptor in the regulation of social recognition in mice
Naoko Yamaguchi; Mumeko C. Tsuda; Shoko Sagoshi; Katsuhiko Nishimori; Toshiro Sakamoto; Sonoko Ogawa
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation
68, E413, E413, 10.1016/j.neures.2010.07.1832

Estrogenic regulation of social behavior: analysis with the use of viral vector-mediated brain site-specific manipulation of gene expression
Sonoto Ogawa; Mumeko C. Tsuda; Kazuhiro Sano; Naoko Yamaguchi; Toshiro Sakamoto; Sergey Mussatov
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2010, Not reviewed, No invitation
60, S37, S37

Neural, hormonal and experiential control of socio-sexual behavior, social recognition and social bonding
Sonoko Ogawa; Mumeko C. Tsuda; Naoko Yamaguchi; Toshiro Sakamoto
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation
68, E8, E8, 10.1016/j.neures.2010.07.266

Role of PPAR gamma in the restraint stress-induced elevation of plasma catecholamines in rats
Shoshiro Okada; Naoko Yamaguchi
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation
68, E394, E394, 10.1016/j.neures.2010.07.1749

Role of brain adrenoceptors in the central CRF-induced sympatho-adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010, Not reviewed, No invitation
112, 172P, 172P

Role of PLC in the centrally administered NMDA-induced adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, Not reviewed, No invitation
109, 255P, 255P

Brain cyclooxygenase and nitric oxide synthase are involved in restraint stress-induced neuronal activation of spinally projecting neurons in rats
Naoko Yamaguchi; Shoshiro Okada
NEUROSCIENCE RESEARCH, 2009, Not reviewed, No invitation
65, S183, S183, 10.1016/j.neures.2009.09.983

Role of brain inflammatory mediators in the restraint stress-induced elevation of plasma catecholamines
Shoshiro Okada; Naoko Yamaguchi
NEUROSCIENCE RESEARCH, 2009, Not reviewed, No invitation
65, S184, S184, 10.1016/j.neures.2009.09.984

Bidirectional roles of the brain 2-arachidonoylglycerol in vasopressin-induced activation of central adrenomedullary outflow in rats
Takahiro Shimizu; Lianyi Lu; Tsuyoshi Sasaki'; Kumiko Nakamura; Naoko Yamaguchi; Shoshiro Okada; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, Not reviewed, No invitation
106, 64P, 64P

Characterization of brain nitric oxide synthase involved in the bombesin-induced activation of central adrenomedullary outflow in rats
Lianyi Lu; Takahiro Shimizu; Kumiko Nakamura; Shoshiro Okada; Naoko Yamaguchi; Tsuyoshi Sasaki; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, Not reviewed, No invitation
106, 177P, 177P

alpha 1 adrenoceptor is involved in the centrally administered NMDA-induced adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi; Takahiro Shimizu; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, Not reviewed, No invitation
106, 242P, 242P

Brain thromboxane A(2) is involved in the centrally administered NMDA-induced adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi; Takahiro Shimizu; Jyunichi Arai; Kunihiko Yokotani
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation
58, S162, S162

Characterization of brain cyclooxygenase involved in the bombesin-induced activation of central adrenomedullary outflow in rats
Lianyi Lu; Takahiro Shimizu; Kumiko Nakamura; Shoshiro Okada; Naoko Yamaguchi; Tsuyoshi Sasaki; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not reviewed, No invitation
103, 131P, 131P

Centrally administered bombesin activates adrenaline- and noradrenaline-containing cells in the adrenal medulla by brain thromboxane A(2)-mediated mechanisms in rats
Naoko Yamaguchi; Shoshiro Okada; Takahiro Shimizu; Daisuke Usui; Kumiko Nakamura; Lianyi Lu; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not reviewed, No invitation
103, 126P, 126P

Role of brain arachidonic acid cascade on the central activation of sympatho-adrenomedullary outflow in rats
Shoshiro Okada; Naoko Yamaguchi; Takahiro Shimizu; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not reviewed, No invitation
103, 23P, 23P

Centrally administered NMDA evoked the secretion of noradrenaline and adrenaline from adrenal medulla by brain thromboxane A(2)-mediated mechanisms in rats
Shoshiro Okada; Naoko Yamaguchi; Takahiro Shimizu; Junich Arai; Liany Lu; Kumiko Nakamura; Mieko Yorimitsu; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not reviewed, No invitation
103, 131P, 131P

Activation of COX isozymes in spinally projecting neurons in the PVN and LC by centrally administered CRF in rats
Naoko Yamaguchi; Shoshiro Okada; Takahiro Shimizu; Daisuke Usui; Kunihiko Yokotani
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation
58, S106, S106

Involvement of brain phosphatidylinositol-specific phospholipase C/diacylglycerol lipase in the histamine-induced activation of central adrenomedullary outflow in rats
Takahiro Shimizu; Shoshiro Okada; Naoko Yamaguchi; Tsuyoshi Sasaki; Kumiko Nakamura; Lianyi Lu; Kunihiko Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, Not reviewed, No invitation
103, 77P, 77P

Role of nitric oxide synthase-containing hypothalamic paraventricular-spinal neurons in the CRF-induced activation of the central sympatho-adrenal outflow in rats
Daisuke Usui; Naoko Yamaguchi; Shoshiro Okada; Takahiro Shimizu; Hiroshi Wakiguchi; Kunihiko Yokotani
NEUROSCIENCE RESEARCH, 2007, Not reviewed, No invitation
58, S161, S161

Role of K+ channels in prostanoid EP3 and TP receptors-mediated inhibition of noradrenaline release from the rat stomach
Nakamura Kumiko; Okada Shoshiro; Yamaguchi Naoko; Shimizu Takahiro; Lu Lianyi; Yokotani Kunihiko
ACTA PHARMACOLOGICA SINICA, Jul. 2006, Not reviewed, No invitation
27, 185, 185

Characterization of brain cyclooxygenase involved in CRF-induced central activation of sympathoadrenomedullary outflow in rats
Lu Lianyi; Okada Shoshiro; Yamaguchi Naoko; Shimizu Takahiro; Nakamura Kumiko; Arai Junichi; Yokotani Kunihiko
ACTA PHARMACOLOGICA SINICA, Jul. 2006, Not reviewed, No invitation
27, 107, 107

Centrally applied GLP-1 activates the sympatho-adrenomedullary outflow by brain prostaglandin-mediated mechanisms in rats
J Arai; S Okada; N Yamaguchi; T Shimizu; LN Lu; K Nakamura; M Yorimitsu; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 190P, 190P

Characterization of brain cyclooxygenase involved in CRF-induced central activation of sympatho-adrenomedullary outflow in rats
LY Lu; S Okada; N Yamaguchi; T Shimizu; K Nakamura; J Arai; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 188P, 188P

Centrally administered histamine evokes the release of noradrenaline and adrenaline from adrenal medulla by brain thromboxane A(2)- and cyclooxygenase-1-mediated mechanisms in rats
T Shimizu; S Okada; N Yamaguchi; T Sasaki; K Nakamura; LY Lu; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 112P, 112P

Adrenal A and NA cells and celiac sympathetic neurons were separately controlled by centrally administered argininevasopressin (AVP) and corticotropin-releasing factor (CRF) in rats
N Yamaguchi; S Okada; T Shimizu; D Usui; LN Lu; K Nakamura; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 85P, 85P

Role of K+ channels in prostanoid EP3 and TP receptors-mediated inhibition of noradrenaline release from the rat stomach
K Nakamura; S Okada; N Yamaguchi; T Shimizu; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 156P, 156P

Central NF-kappa B is involved in the CRF-induced central activation of sympatho-adrenomedullary outflow in rats
S Okada; N Yamaguchi; T Shimizu; J Arai; LN Lu; K Nakamura; M Yorimitsu; A Yamada; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, Not reviewed, No invitation
100, 189P, 189P

Extrahypothalamic corticotropinreleasing factor activates the hypothalamic-pituitary-adrenal axis by activation of the noradrenergic system originated from locus coeruleus in rats
N Yamaguchi; S Okada; T Shimizu; K Yokotani
JOURNAL OF NEUROCHEMISTRY, Aug. 2005, Not reviewed, No invitation
94, 254, 254

Role of K+ channels in prostanoid EP3 and TP receptors-mediated inhibition of noradrenaline release from the rat stomach
KM Nakamura; S Okada; N Yamaguchi; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, Not reviewed, No invitation
97, 173P, 173P

Brain phospholipase C/diacylglycerol lipase is involved in the bombesin BB2 receptor-mediated activation of sympatho-adrenomedullary outflow in rats
T Shimizu; S Okada; N Yamaguchi; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, Not reviewed, No invitation
97, 73P, 73P

Extrahypothalamic CRF activates the hypothalamic-pituitary-adrenal axis by activation of the noradrenergic system originated from locus coeruleus in rats
N Yamaguchi; S Okada; T Shimizu; LY Lu; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, Not reviewed, No invitation
97, 166P, 166P

Spinal substance P is involved in the vasopressin-induced central activation of adrenomedullary outflow in rats
S Okada; N Yamaguchi; T Shimizu; J Arai; K Nakamura; Y Hijioka; LY Lu; K Yokotani
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, Not reviewed, No invitation
97, 273P, 273P

副腎髄質からのノルアドレナリン及びアドレナリン分泌の選択的な中枢性調節機序 -脳内アラキドン酸カスケード系との関連について-
岡田尚志郎; 清水孝洋; 山口奈緒子; 横谷邦彦
The Autonomic Nervous System (Journal of the Japan Society of Neurovegetative Research), 2004, Reviewed, No invitation
41, 411, 415

うつ病での糖代謝異常の脳内調節機構におけるトロンボキサンA2の役割
Apr. 2021 - Mar. 2024
岡田尚志郎, 岡田尚志郎, 科学研究費補助金（基盤C）, 科学研究費補助金（基盤C）, Coinvestigator

ストレス応答の異常な持続的亢進をもたらす脳内機序の解明
Apr. 2020 - Mar. 2023
山口奈緒子, 山口奈緒子, 科学研究費補助金（基盤C）, 科学研究費補助金（基盤C）, Principal investigator

室傍核におけるノルアドレナリン神経系−CRF連関はストレス反応持続に関与するか？
Apr. 2017 - Mar. 2020
岡田尚志郎, 岡田尚志郎, 科学研究費補助金（基盤C）, 科学研究費補助金（基盤C）, Coinvestigator

ストレス応答調節におけるネガティブ・フィードバック破綻の機序の解明
Apr. 2016 - Mar. 2019
山口 奈緒子, 山口 奈緒子, Principal investigator

拘束ストレスに誘発される交感神経反応に対する抑肝散の効果
2019 - 2019
岡田尚志郎, 岡田尚志郎, 東洋医学研究財団 第42回研究・調査助成金, 東洋医学研究財団 第42回研究・調査助成金, Coinvestigator

ストレス脆弱性の発生機構の解明−思春期のストレス経験が及ぼす影響−
Apr. 2013 - Mar. 2016
山口 奈緒子, 山口 奈緒子, Principal investigator

高齢期におけるストレス脆弱性の神経基盤とその性差の解明
Apr. 2012 - Mar. 2015
由利 和也, 由利 和也, Coinvestigator

ストレスによる社会行動変容におけるオキシトシン−オキシトシン受容体システムの役割
Apr. 2011 - Mar. 2013
山口 奈緒子, 山口 奈緒子, Principal investigator

拘束ストレスにより誘導される脳内因子の解析−交感神経系亢進持続の観点から−
Apr. 2009 - Mar. 2011
山口 奈緒子, 山口 奈緒子, Principal investigator

Roles of endocannabinoid in the modulation of central sympatho-adrenomedullary outflow in rat
Grant-in-Aid for Scientific Research (C)
Kochi University
2008 - 2010
横谷 邦彦; 清水 孝洋; 田中 健二朗; 山口 奈緒子, YOKOTANI Kunihiko; SHIMIZU Takahiro; TANAKA Kenjirou, 日本学術振興会, Japan Society for the Promotion of Science

ニコチンによる交感神経−副腎髄質系賦活に関与する脳内機構の解析
Apr. 2006 - Mar. 2009
岡田 尚志郎, 岡田 尚志郎, Coinvestigator

視床下部室傍核−青斑核ニューロサーキットは持続性高コルチゾール症に関与するか？
Apr. 2005 - Mar. 2007
岡田尚志郎, 岡田尚志郎, 科学研究費補助金（基盤C）, 科学研究費補助金（基盤C）, Coinvestigator

Stress-induced activation of sympatho-adrenomedullary system

Estrogen receptor-related mechanism of stress responses