2012年04月01日 - 現在
臨床系コア・カリキュラム ワーキンググループ, 委員

Associations of frailty with RA-ILD and poor control of disease activity in patients with rheumatoid arthritis: A multi-center retrospective observational study.
Yoshifumi Ohashi; Nobunori Takahashi; Yasumori Sobue; Mochihito Suzuki; Ryo Sato; Masataka Maeda; Daisuke Kihira; Kenji Kishimoto; Kenya Terabe; Shuji Asai; Shiro Imagama
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2023年12月
10.1016/j.jos.2023.11.012

Well-controlled disease activity with drug treatment will not improve the frailty status of RA patients to robust state: A multicenter observational study (T-FLAG).
Yoshifumi Ohashi; Nobunori Takahashi; Yasumori Sobue; Mochihito Suzuki; Ryo Sato; Masataka Maeda; Kenya Terabe; Shuji Asai; Shiro Imagama
International journal of rheumatic diseases, 2023年11月
10.1111/1756-185X.14946

Periprosthetic humeral fracture revision using a massive allograft in a patient with rheumatoid arthritis: A case report.
Kenji Kishimoto; Toshihisa Kojima; Nobunori Takahashi; Shuji Asai; Kenya Terabe; Mochihito Suzuki; Yoshifumi Ohashi; Daisuke Kihira; Masataka Maeda; Masahiro Tatebe; Shiro Imagama
Modern rheumatology case reports, 2023年06月
7(2), 359, 363, 10.1093/mrcr/rxad001

Effectiveness of tacrolimus concomitant with biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritis.
Kenya Terabe; Nobunori Takahashi; Shuji Asai; Yuji Hirano; Yasuhide Kanayama; Yuichiro Yabe; Takeshi Oguchi; Takayoshi Fujibayashi; Hisato Ishikawa; Masahiro Hanabayashi; Yosuke Hattori; Mochihito Suzuki; Kenji Kishimoto; Yoshifumi Ohashi; Takahiro Imaizumi; Shiro Imagama; Toshihisa Kojima
Modern rheumatology, 2023年03月
33(2), 292, 301, 10.1093/mr/roac025

Patient-Specific Femoral Guide with 3-Dimensional Support Software in Anterolateral Supine Approach of Total Hip Arthroplasty: A Single-Arm Trial.
Daihei Kida; Hiroya Hashimoto; Noriko Ito; Yukari Kito; Kouichi Mori; Yosuke Hattori; Nobunori Takahashi; Masaaki Matsubara
The Kurume medical journal, 2023年02月
68(1), 1, 8, 10.2739/kurumemedj.MS681003

Disease activity at baseline is an independent predictor of frailty at one year in pre-frail patients with rheumatoid arthritis; a multicenter retrospective observational study.
Yoshifumi Ohashi; Nobunori Takahashi; Yasumori Sobue; Mochihito Suzuki; Kyosuke Hattori; Kenji Kishimoto; Kenya Terabe; Shuji Asai; Toshihisa Kojima; Masayo Kojima; Shiro Imagama
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2022年11月
10.1016/j.jos.2022.10.025

Locomotive syndrome in rheumatoid arthritis patients during the COVID-19 pandemic.
Yasumori Sobue; Mochihito Suzuki; Yoshifumi Ohashi; Hiroshi Koshima; Nobuyuki Okui; Koji Funahashi; Hisato Ishikawa; Hidenori Inoue; Masayo Kojima; Shuji Asai; Kenya Terabe; Kyosuke Hattori; Kenji Kishimoto; Nobunori Takahashi; Shiro Imagama; Toshihisa Kojima
Nagoya journal of medical science, 2022年11月
84(4), 799, 812, 10.18999/nagjms.84.4.799

Increased prevalence of Staphylococcus aureus nasal carriage in rheumatoid arthritis patients with moderate/high disease activity.
Shuji Asai; Nobunori Takahashi; Kenji Kishimoto; Mochihito Suzuki; Yoshifumi Ohashi; Kenya Terabe; Toshihisa Kojima; Shiro Imagama
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2022年10月
10.1016/j.jos.2022.09.014

Association between locomotive syndrome and methotrexate discontinuation due to adverse events in rheumatoid arthritis patients: A retrospective observational study.
Yasumori Sobue; Mochihito Suzuki; Yoshifumi Ohashi; Hiroshi Koshima; Nobuyuki Okui; Koji Funahashi; Hisato Ishikawa; Hidenori Inoue; Masayo Kojima; Shuji Asai; Kenya Terabe; Kyosuke Hattori; Kenji Kishimoto; Nobunori Takahashi; Shiro Imagama; Toshihisa Kojima
Geriatrics & gerontology international, 2022年10月
22(10), 904, 905, 10.1111/ggi.14475

Reasons and Risk Factors For Discontinuation of Treatment with Any Biological Disease-Modifying Antirheumatic Drugs in Patients with Rheumatoid Arthritis: A Long-term Observational Study.
Kenya Terabe; Nobunori Takahashi; Shuji Asai; Yuji Hirano; Yasuhide Kanayama; Yuichiro Yabe; Takeshi Oguchi; Takayoshi Fujibayashi; Hisato Ishikawa; Masahiro Hanabayashi; Yosuke Hattori; Mochihito Suzuki; Kenji Kishimoto; Yoshifumi Ohashi; Takahiro Imaizumi; Shiro Imagama; Toshihisa Kojima
Modern rheumatology, 2022年08月
10.1093/mr/roac090

Influence of frailty on patient global assessment in rheumatoid arthritis.
Mochihito Suzuki; Shuji Asai; Yasumori Sobue; Yoshifumi Ohashi; Hiroshi Koshima; Nobuyuki Okui; Hisato Ishikawa; Nobunori Takahashi; Kenya Terabe; Kenji Kishimoto; Kyosuke Hattori; Shiro Imagama; Toshihisa Kojima
Geriatrics & gerontology international, 2022年05月
22(5), 399, 404, 10.1111/ggi.14375

Changes in perioperative C-reactive protein levels in patients with rheumatoid arthritis undergoing total knee arthroplasty in the biologic era.
Kenji Kishimoto; Shuji Asai; Nobunori Takahashi; Kenya Terabe; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Naoki Ishiguro; Toshihisa Kojima
Nagoya journal of medical science, 2022年05月
84(2), 286, 300, 10.18999/nagjms.84.2.286

Factors Associated With Frailty in Rheumatoid Arthritis Patients With Decreased Renal Function.
Yoshifumi Ohashi; Nobunori Takahashi; Yasumori Sobue; Mochihito Suzuki; Kyosuke Hattori; Kenji Kishimoto; Kenya Terabe; Syuji Asai; Toshihisa Kojima; Masayo Kojima; Shiro Imagama
Modern rheumatology, 2022年04月
33(2), 323, 329, 10.1093/mr/roac018

Relationship between locomotive syndrome and frailty in rheumatoid arthritis patients by locomotive syndrome stage.
Yasumori Sobue; Mochihito Suzuki; Yoshifumi Ohashi; Hiroshi Koshima; Nobuyuki Okui; Koji Funahashi; Hisato Ishikawa; Shuji Asai; Kenya Terabe; Yutaka Yokota; Kenji Kishimoto; Nobunori Takahashi; Shiro Imagama; Toshihisa Kojima
Modern rheumatology, 2022年04月
32(3), 546, 553, 10.1093/mr/roab024

The Efficacy and Safety of a Novel Extramedullary Guide Coordinated with 3D Surgical Assistive Software for Total Knee Arthroplasty: an Open-Label Single-Arm Trial
DAIHEI KIDA; HIROYA HASHIMOTO; AKIKO M. SAITO; YUKARI KITO; YOSUKE HATTORI; KENYA TERABE; KOUICHI MORI; NOBUNORI TAKAHASHI; YASUSHI TOMITA
The Kurume Medical Journal, 2021年11月
10.2739/kurumemedj.ms671002

Impact of social support on severity of depressive symptoms by remission status in patients with rheumatoid arthritis
Mikako Yasuoka; Toshihisa Kojima; Yuko Waguri-Nagaya; Tami Saito; Nobunori Takahashi; Shuji Asai; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Hiroto Mitsui; Yohei Kawaguchi; Gen Kuroyanagi; Koto Kamiji; Miki Watanabe; Sadao Suzuki; Katsunori Kondo; Toshiyuki Ojima; Masayo Kojima
Modern Rheumatology, 2021年08月
10.1093/mr/roab001

Comparison of the effects of baricitinib and tocilizumab on disease activity in patients with rheumatoid arthritis: a propensity score matching analysis.
Shuji Asai; Nobunori Takahashi; Tomonori Kobayakawa; Atsushi Kaneko; Tatsuo Watanabe; Takefumi Kato; Tsuyoshi Nishiume; Hisato Ishikawa; Yutaka Yoshioka; Yasuhide Kanayama; Tsuyoshi Watanabe; Yuji Hirano; Masahiro Hanabayashi; Yuichiro Yabe; Yutaka Yokota; Mochihito Suzuki; Kenya Terabe; Naoki Ishiguro; Shiro Imagama; Toshihisa Kojima
Clinical rheumatology, 2021年08月
40(8), 3143, 3151, 10.1007/s10067-021-05815-3

Higher doses of methotrexate associated with discontinuation of oral glucocorticoids after initiation of biological DMARDs: A retrospective observational study based on data from a Japanese multicenter registry study.
Mochihito Suzuki; Toshihisa Kojima; Nobunori Takahashi; Shuji Asai; Kenya Terabe; Atsushi Kaneko; Yuji Hirano; Masahiro Hanabayashi; Takeshi Oguchi; Hideki Takagi; Yasuhide Kanayama; Yuichiro Yabe; Koji Funahashi; Takayoshi Fujibayashi; Seiji Tsuboi; Takayasu Ito; Yutaka Yoshioka; Hisato Ishikawa; Yasumori Sobue; Tsuyoshi Nishiume; Yutaka Yokota; Naoki Ishiguro
Modern rheumatology, 2021年07月
31(4), 796, 802, 10.1080/14397595.2021.1879428

Fifteen-year trends in the number and age of patients with rheumatoid arthritis undergoing total knee and hip arthroplasty: A comparison study with osteoarthritis
Shuji Asai; Toki Takemoto; Nobunori Takahashi; Takeshi Oguchi; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2021年
31(3), 768, 771, 10.1080/14397595.2020.1812794

Efficacy of add-on iguratimod in patients with rheumatoid arthritis who inadequately respond to either tocilizumab or tumor necrosis factor alpha inhibitors
Kyosuke Hattori; Yuji Hirano; Yasuhide Kanayama; Yosuke Hattori; Takefumi Kato; Nobunori Takahashi; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2021年
31(1), 80, 87, 10.1080/14397595.2020.1740390

Relationship between disease activity of rheumatoid arthritis and development of locomotive syndrome: A five-year longitudinal cohort study.
Yasumori Sobue; Toshihisa Kojima; Koji Funahashi; Nobuyuki Okui; Nobunori Takahashi; Shuji Asai; Kenya Terabe; Tsuyoshi Nishiume; Mochihito Suzuki; Yutaka Yokota; Yoshifumi Ohashi; Naoki Ishiguro
Modern rheumatology, 2021年01月
31(1), 101, 107, 10.1080/14397595.2020.1744828

Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry.
Nobunori Takahashi; Shuji Asai; Tomonori Kobayakawa; Atsushi Kaneko; Tatsuo Watanabe; Takefumi Kato; Tsuyoshi Nishiume; Hisato Ishikawa; Yutaka Yoshioka; Yasuhide Kanayama; Tsuyoshi Watanabe; Yuji Hirano; Masahiro Hanabayashi; Yuichiro Yabe; Yutaka Yokota; Mochihito Suzuki; Yasumori Sobue; Kenya Terabe; Naoki Ishiguro; Toshihisa Kojima
Scientific reports, 2020年12月
10(1), 21907, 21907, 10.1038/s41598-020-78925-8

A retrospective analysis of the relationship between anti-cyclic citrullinated peptide antibody and the effectiveness of abatacept in rheumatoid arthritis patients.
Daihei Kida; Nobunori Takahashi; Atsushi Kaneko; Yuji Hirano; Takayoshi Fujibayashi; Yasuhide Kanayama; Masahiro Hanabayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Takefumi Kato; Koji Funahashi; Takuya Matsumoto; Masahiko Ando; Yachiyo Kuwatsuka; Eiichi Tanaka; Hidekata Yasuoka; Yuko Kaneko; Shintaro Hirata; Kosaku Murakami; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Yutaka Yokota; Kenya Terabe; Shuji Asai; Naoki Ishiguro; Toshihisa Kojima
Scientific reports, 2020年11月
10(1), 19717, 19717, 10.1038/s41598-020-76842-4

Depression, physical function, and disease activity associated with frailty in patients with rheumatoid arthritis.
Masayo Kojima; Toshihisa Kojima; Yuko Waguri-Nagaya; Nobunori Takahashi; Shuji Asai; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Hiroto Mitsui; Yohei Kawaguchi; Gen Kuroyanagi; Mikako Yasuoka; Miki Watanabe; Sadao Suzuki; Hidenori Arai
Modern rheumatology, 2020年11月
1, 8, 10.1080/14397595.2020.1838402

Periarticular osteophyte formation protects against total knee arthroplasty in rheumatoid arthritis patients with advanced joint damage.
Shuji Asai; Nobunori Takahashi; Kenya Terabe; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Yutaka Yokota; Naoki Ishiguro; Toshihisa Kojima
Clinical rheumatology, 2020年11月
39(11), 3331, 3339, 10.1007/s10067-020-05140-1

Factors associated with osteophyte formation in patients with rheumatoid arthritis undergoing total knee arthroplasty
Nobuyuki Asai; Shuji Asai; Nobunori Takahashi; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2020年09月
30(5), 937, 939, 10.1080/14397595.2019.1673132

Characteristics of patients with rheumatoid arthritis undergoing primary total joint replacement: A 14-year trend analysis (2004-2017).
Shuji Asai; Nobunori Takahashi; Nobuyuki Asai; Satoshi Yamashita; Kenya Terabe; Takuya Matsumoto; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Naoki Ishiguro; Toshihisa Kojima
Modern rheumatology, 2020年07月
30(4), 657, 663, 10.1080/14397595.2019.1649111

Discontinuation of concomitant methotrexate in Japanese patients with rheumatoid arthritis treated with tocilizumab: An interventional study
Shuji Asai; Masatoshi Hayashi; Masahiro Hanabayashi; Yasuhide Kanayama; Toki Takemoto; Yuichiro Yabe; Tomone Shioura; Hisato Ishikawa; Yutaka Yoshioka; Takefumi Kato; Yuji Hirano; Takayoshi Fujibayashi; Yosuke Hattori; Tomonori Kobayakawa; Masahiko Ando; Yachiyo Kuwatsuka; Nobunori Takahashi; Takuya Matsumoto; Nobuyuki Asai; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2020年05月
30(3), 434, 441, 10.1080/14397595.2019.1641934

Improvement in matrix metalloproteinase-3 independently predicts low disease activity at 52 weeks in bio-switch rheumatoid arthritis patients treated with abatacept.
Toki Takemoto; Nobunori Takahashi; Daihei Kida; Atsushi Kaneko; Yuji Hirano; Takayoshi Fujibayashi; Yasuhide Kanayama; Masahiro Hanabayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Takefumi Kato; Koji Funahashi; Takuya Matsumoto; Yasumori Sobue; Tsuyoshi Nishiume; Mochihito Suzuki; Yutaka Yokota; Kenya Terabe; Shuji Asai; Naoki Ishiguro; Toshihisa Kojima
Clinical and experimental rheumatology, 2020年
38(5), 933, 939

Clinical effectiveness and safety of additional administration of tacrolimus in rheumatoid arthritis patients with an inadequate response to abatacept: A retrospective cohort study
Mochihito Suzuki; Nobunori Takahashi; Daihei Kida; Yuji Hirano; Takefumi Kato; Yuichiro Yabe; Takeshi Oguchi; Takayoshi Fujibayashi; Masatoshi Hayashi; Shuji Asai; Naoki Ishiguro; Toshihisa Kojima
International Journal of Rheumatic Diseases, 2019年12月
22(12), 2199, 2205, 10.1111/1756-185X.13731

Association between seropositivity and discontinuation of tumor necrosis factor inhibitors due to ineffectiveness in rheumatoid arthritis
Yoshikazu Ogawa; Nobunori Takahashi; Atsushi Kaneko; Yuji Hirano; Yasuhide Kanayama; Yuichiro Yabe; Takeshi Oguchi; Takayoshi Fujibayashi; Hideki Takagi; Masahiro Hanabayashi; Koji Funahashi; Masatoshi Hayashi; Seiji Tsuboi; Shuji Asai; Nobuyuki Asai; Takuya Matsumoto; Yasumori Sobue; Naoki Ishiguro; Toshihisa Kojima
Clinical Rheumatology, 2019年10月
38(10), 2757, 2763, 10.1007/s10067-019-04626-x

Concomitant methotrexate has little effect on clinical outcomes of abatacept in rheumatoid arthritis: a propensity score matching analysis.
Takahashi N; Kojima T; Kida D; Kaneko A; Hirano Y; Fujibayashi T; Yabe Y; Takagi H; Oguchi T; Hanabayashi M; Kato T; Funahashi K; Hayashi M; Tsuboi S; Kanayama Y; Sobue Y; Asai N; Matsumoto T; Watanabe T; Asai S; Ishiguro N
Clinical rheumatology, 2019年05月, 査読有り, 招待無し
10.1007/s10067-019-04581-7

Computed tomography evaluation of the periacetabular gap of a porous tantalum acetabular component.
Asai S; Sobue Y; Asai N; Takahashi N; Watanabe T; Matsumoto T; Ishiguro N; Kojima T
Nagoya journal of medical science, 2019年02月, 査読有り, 招待無し
81(1), 159, 163, 10.18999/nagjms.81.1.159

Simvastatin promotes restoration of chondrocyte morphology and phenotype.
Terabe K; Takahashi N; Cobb M; Askew EB; Knudson CB; Knudson W
Archives of biochemistry and biophysics, 2019年02月, 査読有り, 招待無し
665, 1, 11, 10.1016/j.abb.2019.01.038

Predictors of denosumab efficacy in treating osteoporosis in patients with rheumatoid arthritis: A Japanese multicenter study
Kyosuke Hattori; Yuji Hirano; Yasuhide Kanayama; Nobunori Takahashi; Naoki Ishiguro; Toshihisa Kojima
Nagoya Journal of Medical Science, 2019年
81(4), 571, 585, 10.18999/nagjms.81.4.571

Longitudinal changes in pulmonary function and respiratory impedance of rheumatoid arthritis.
Isobe Y; Ito S; Matsuda T; Iwano S; Uchida A; Takahashi N; Kojima T; Wakahara K; Yamaguchi E; Hasegawa Y
Respiratory physiology & neurobiology, 2018年12月, 査読有り, 招待無し
261, 1, 8, 10.1016/j.resp.2018.12.008

Association between chest computed tomography findings and respiratory adverse events in rheumatoid arthritis patients undergoing long-term biological therapy.
Matsumoto T; Iwano S; Takahashi N; Asai S; Watanabe T; Asai N; Sobue Y; Ito S; Ishiguro N; Kojima T
International journal of rheumatic diseases, 2018年11月, 査読有り, 招待無し
10.1111/1756-185X.13434

An Open-Label, Single-Arm Study of a Patient-Specific Femoral Guide for Total Hip Arthroplasty via the Anterolateral Supine Approach, Linked with Three-Dimensional Surgical Support Software: Study Protocol.
Kida D; Hashimoto H; Ito N; Kito Y; Mori K; Takahashi N; Tomita Y
The Kurume medical journal, 2018年09月, 査読有り, 招待無し
65(2), 71, 75, 10.2739/kurumemedj.MS652002

Clinical effectiveness and long-term retention of abatacept in elderly rheumatoid arthritis patients: Results from a multicenter registry system.
Takahashi N; Kojima T; Kida D; Kaneko A; Hirano Y; Fujibayashi T; Yabe Y; Takagi H; Oguchi T; Hanabayashi M; Kato T; Funahashi K; Hayashi M; Tsuboi S; Kanayama Y; Sobue Y; Asai N; Matsumoto T; Watanabe T; Asai S; Ishiguro N
Modern rheumatology, 2018年09月, 査読有り, 招待無し
1, 23, 10.1080/14397595.2018.1525019

An Open-label Single-arm Trial of a Novel Extramedullary Guide Coordinated with 3D Surgical Assistive Software for Total Knee Arthroplasty.
Kida D; Hashimoto H; Saito AM; Kito Y; Mori K; Terabe K; Takahashi N; Tomita Y
Acta medica Okayama, 2018年08月, 査読有り, 招待無し
72(4), 441, 445, 10.18926/AMO/56186

Influence of methotrexate on gastrointestinal symptoms in patients with rheumatoid arthritis.
Asai S; Nagai K; Takahashi N; Watanabe T; Matsumoto T; Asai N; Sobue Y; Ishiguro N; Kojima T
International journal of rheumatic diseases, 2018年08月, 査読有り, 招待無し
10.1111/1756-185X.13380

Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study
Shuji Asai; Takayoshi Fujibayashi; Takeshi Oguchi; Masahiro Hanabayashi; Masatoshi Hayashi; Hiroyuki Matsubara; Takayasu Ito; Yuichiro Yabe; Tsuyoshi Watanabe; Yuji Hirano; Yasuhide Kanayama; Atsushi Kaneko; Takefumi Kato; Hideki Takagi; Nobunori Takahashi; Koji Funahashi; Toki Takemoto; Nobuyuki Asai; Tatsuo Watanabe; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2018年03月, 査読有り, 招待無し
28(2), 221, 226, 10.1080/14397595.2017.1332558

High rate of improvement in serum matrix metalloproteinase-3 levels at 4 weeks predicts remission at 52 weeks in RA patients treated with adalimumab
Yosuke Hattori; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Takeshi Oguchi; Yasuhide Kanayama; Hiroyuki Miyake; Takefumi Kato; Hideki Takagi; Masatoshi Hayashi; Takayasu Ito; Tomone Shioura; Nobunori Takahashi; Hisato Ishikawa; Koji Funahashi; Naoki Ishiguro
Modern Rheumatology, 2018年01月, 査読有り, 招待無し
28(1), 119, 125, 10.1080/14397595.2017.1317320

Patient-reported outcomes as assessment tools and predictors of long-term prognosis: a 7-year follow-up study of patients with rheumatoid arthritis
Masayo Kojima; Toshihisa Kojima; Sadao Suzuki; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Yutaka Yoshioka; Kenya Terabe; Nobuyuki Asai; Toki Takemoto; Naoki Ishiguro
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2017年09月, 査読有り, 招待無し
20(9), 1193, 1200, 10.1111/1756-185X.12789

Two cases of autoimmune pulmonary alveolar proteinosis with rheumatoid arthritis
Satoru Ito; Keiko Wakahara; Toshihisa Kojima; Nobunori Takahashi; Kimitoshi Nishiwaki; Etsuro Yamaguchi; Yoshinori Hasegawa
ALLERGOLOGY INTERNATIONAL, 2017年07月, 査読有り, 招待無し
66(3), 507, 509, 10.1016/j.alit.2017.02.002

Mechanical stress loading induces CD44 cleavage in human chondrocytic HCS-2/8 cells
Tomonori Kobayakawa; Nobunori Takahashi; Yasumori Sobue; Kenya Terabe; Naoki Ishiguro; Toshihisa Kojima
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016年09月, 査読有り, 招待無し
478(3), 1230, 1235, 10.1016/j.bbrc.2016.08.099

Simvastatin inhibits CD44 fragmentation in chondrocytes
Kenya Terabe; Nobunori Takahashi; Toki Takemoto; Warren Knudson; Naoki Ishiguro; Toshihisa Kojima
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2016年08月, 査読有り, 招待無し
604, 1, 10, 10.1016/j.abb.2016.05.019

Longterm Retention Rate and Risk Factors for Adalimumab Discontinuation Due To Efficacy and Safety in Japanese Patients with Rheumatoid Arthritis: An Observational Cohort Study
Yosuke Hattori; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Kenya Terabe; Yuichiro Yabe; Hiroyuki Miyake; Takefumi Kato; Hideki Takagi; Masatoshi Hayashi; Takayasu Ito; Yasuhide Kanayama; Takeshi Oguchi; Nobunori Takahashi; Hisato Ishikawa; Koji Funahashi; Naoki Ishiguro
JOURNAL OF RHEUMATOLOGY, 2016年08月, 査読有り, 招待無し
43(8), 1475, 1479, 10.3899/jrheum.151006

Hyaluronan Oligosaccharides Induce MMP-1 and -3 via Transcriptional Activation of NF-κB and p38 MAPK in Rheumatoid Synovial Fibroblasts.
Hanabayashi M; Takahashi N; Sobue Y; Hirabara S; Ishiguro N; Kojima T
PloS one, 2016年08月, 査読有り, 招待無し
11(8), e0161875, 10.1371/journal.pone.0161875

Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages
Takuya Matsumoto; Nobunori Takahashi; Toshihisa Kojima; Yutaka Yoshioka; Jun Ishikawa; Koichi Furukawa; Kenji Ono; Makoto Sawada; Naoki Ishiguro; Akihito Yamamoto
ARTHRITIS RESEARCH & THERAPY, 2016年06月, 査読有り, 招待無し
18(1), 133, 10.1186/s13075-016-1035-9

[Mechanism of action of biological disease--modifying antirheumatic drugs].
Takahashi N; Ishiguro N
Nihon rinsho. Japanese journal of clinical medicine, 2016年06月, 査読有り, 招待無し
74(6), 882, 886

Improved safety of biologic therapy for rheumatoid arthritis over the 8-year period since implementation in Japan: long-term results from a multicenter observational cohort study
Toshihisa Kojima; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Kenya Terabe; Atsushi Kaneko; Yuji Hirano; Masatoshi Hayashi; Hiroyuki Miyake; Takeshi Oguchi; Hideki Takagi; Yasuhide Kanayama; Yuichiro Yabe; Tsuyoshi Watanabe; Takayoshi Fujibayashi; Tomone Shioura; Takayasu Ito; Yutaka Yoshioka; Hisato Ishikawa; Nobuyuki Asai; Toki Takemoto; Masayo Kojima; Naoki Ishiguro
CLINICAL RHEUMATOLOGY, 2016年04月, 査読有り, 招待無し
35(4), 863, 871, 10.1007/s10067-016-3201-5

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis
Yuhsuke Ohmi; Wataru Ise; Akira Harazono; Daisuke Takakura; Hidehiro Fukuyama; Yoshihiro Baba; Masashi Narazaki; Hirofumi Shoda; Nobunori Takahashi; Yuki Ohkawa; Shuting Ji; Fumihiro Sugiyama; Keishi Fujio; Atsushi Kumanogoh; Kazuhiko Yamamoto; Nana Kawasaki; Tomohiro Kurosaki; Yoshimasa Takahashi; Koichi Furukawa
NATURE COMMUNICATIONS, 2016年04月, 査読有り, 招待無し
7, 11205, 10.1038/ncomms11205

Hyaluronan Inhibits Tlr-4-Dependent RANKL Expression in Human Rheumatoid Arthritis Synovial Fibroblasts
Tatsuo Watanabe; Nobunori Takahashi; Shinya Hirabara; Naoki Ishiguro; Toshihisa Kojima
PLOS ONE, 2016年04月, 査読有り, 招待無し
11(4), e0153142, 10.1371/journal.pone.0153142

Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis
Jun Ishikawa; Nobunori Takahashi; Takuya Matsumoto; Yutaka Yoshioka; Noriyuki Yamamoto; Masaya Nishikawa; Hideharu Hibi; Naoki Ishigro; Minoru Ueda; Koichi Furukawa; Akihito Yamamoto
BONE, 2016年02月, 査読有り, 招待無し
83, 210, 219, 10.1016/j.bone.2015.11.012

Disease activity early in treatment as a predictor of future low disease activity in RA patients treated with iguratimod
Yutaka Yoshioka; Nobunori Takahashi; Atsushi Kaneko; Yuji Hirano; Yasuhide Kanayama; Hiroyasu Kanda; Hideki Takagi; Takayasu Ito; Takefumi Kato; Kiwamu Saito; Koji Funahashi; Shuji Asai; Toki Takemoto; Kenya Terabe; Nobuyuki Asai; Naoki Ishiguro; Toshihisa Kojima
MODERN RHEUMATOLOGY, 2016年, 査読有り, 招待無し
26(2), 169, 174, 10.3109/14397595.2015.1069475

Predictive factors for achieving low disease activity at 52 weeks after switching from tumor necrosis factor inhibitors to abatacept: results from a multicenter observational cohort study of Japanese patients
Toshihisa Kojima; Nobunori Takahashi; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Takefumi Kato; Tsuyoshi Watanabe; Masatoshi Hayashi; Tomone Shioura; Yasuhide Kanayama; Koji Funahashi; Shuji Asai; Yutaka Yoshioka; Kenya Terabe; Toki Takemoto; Nobuyuki Asai; Naoki Ishiguro
CLINICAL RHEUMATOLOGY, 2016年01月, 査読有り, 招待無し
35(1), 219, 225, 10.1007/s10067-015-3135-3

Concomitant Methotrexate Protects Against Total Knee Arthroplasty in Patients with Rheumatoid Arthritis Treated with Tumor Necrosis Factor Inhibitors
Shuji Asai; Nobunori Takahashi; Koji Funahashi; Yutaka Yoshioka; Toki Takemoto; Kenya Terabe; Nobuyuki Asai; Naoki Ishiguro; Toshihisa Kojima
JOURNAL OF RHEUMATOLOGY, 2015年12月, 査読有り, 招待無し
42(12), 2255, 2260, 10.3899/jrheum.150410

[Regenerative medicine for cartilage defect in rheumatic disease].
Takahashi N; Ishiguro N
Clinical calcium, 2015年12月, 査読有り, 招待無し
25(12), 1801, 1807

Effects of Concomitant Methotrexate on Large Joint Replacement in Patients With Rheumatoid Arthritis Treated With Tumor Necrosis Factor Inhibitors: A Multicenter Retrospective Cohort Study in Japan
Shuji Asai; Toshihisa Kojima; Takeshi Oguchi; Atsushi Kaneko; Yuji Hirano; Yuichiro Yabe; Yasuhide Kanayama; Nobunori Takahashi; Koji Funahashi; Masahiro Hanabayashi; Shinya Hirabara; Yutaka Yoshioka; Toki Takemoto; Kenya Terabe; Nobuyuki Asai; Naoki Ishiguro
ARTHRITIS CARE & RESEARCH, 2015年10月, 査読有り, 招待無し
67(10), 1363, 1370, 10.1002/acr.22596

Concomitant methotrexate and tacrolimus augment the clinical response to abatacept in patients with rheumatoid arthritis with a prior history of biological DMARD use
Nobunori Takahashi; Takayoshi Fujibayashi; Daihei Kida; Yuji Hirano; Takefumi Kato; Daizo Kato; Kiwamu Saito; Atsushi Kaneko; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Tsuyoshi Watanabe; Masatoshi Hayashi; Yasuhide Kanayama; Koji Funahashi; Masahiro Hanabayashi; Shinya Hirabara; Shuji Asai; Toki Takemoto; Kenya Terabe; Nobuyuki Asai; Yutaka Yoshioka; Naoki Ishiguro; Toshihisa Kojima
RHEUMATOLOGY INTERNATIONAL, 2015年10月, 査読有り, 招待無し
35(10), 1707, 1716, 10.1007/s00296-015-3283-4

Use of a 12-week observational period for predicting low disease activity at 52 weeks in RA patients treated with abatacept: a retrospective observational study based on data from a Japanese multicentre registry study
Nobunori Takahashi; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Takefumi Kato; Naoki Fukaya; Masatoshi Hayashi; Seiji Tsuboi; Yasuhide Kanayama; Koji Funahashi; Masahiro Hanabayashi; Shinya Hirabara; Shuji Asai; Yutaka Yoshioka; Naoki Ishiguro
RHEUMATOLOGY, 2015年05月, 査読有り, 招待無し
54(5), 854, 859, 10.1093/rheumatology/keu418

Longterm Efficacy and Safety of Abatacept in Patients with Rheumatoid Arthritis Treated in Routine Clinical Practice: Effect of Concomitant Methotrexate after 24 Weeks
Nobunori Takahashi; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Takefumi Kato; Tsuyoshi Watanabe; Masatoshi Hayashi; Yasuhide Kanayama; Koji Funahashi; Shuji Asai; Yutaka Yoshioka; Toki Takemoto; Kenya Terabe; Nobuyuki Asai; Naoki Ishiguro
JOURNAL OF RHEUMATOLOGY, 2015年05月, 査読有り, 招待無し
42(5), 786, 793, 10.3899/jrheum.141288

Drug retention rates of second biologic agents after switching from tumor necrosis factor inhibitors for rheumatoid arthritis in Japanese patients on low-dose methotrexate or without methotrexate
Tomonori Kobayakawa; Toshihisa Kojima; Nobunori Takahashi; Masatoshi Hayashi; Yuichiro Yabe; Atsushi Kaneko; Tomone Shioura; Kiwamu Saito; Yuji Hirano; Yasuhide Kanayama; Hiroyuki Miyake; Nobuyuki Asai; Koji Funahashi; Shinya Hirabara; Masahiro Hanabayashi; Shuji Asai; Naoki Ishiguro
MODERN RHEUMATOLOGY, 2015年03月, 査読有り, 招待無し
25(2), 251, 256, 10.3109/14397595.2014.953668

Importance of methotrexate therapy concomitant with tocilizumab treatment in achieving better clinical outcomes for rheumatoid arthritis patients with high disease activity: an observational cohort study
Toshihisa Kojima; Yuichiro Yabe; Atsushi Kaneko; Nobunori Takahashi; Koji Funahashi; Daizo Kato; Masahiro Hanabayashi; Shuji Asai; Shinya Hirabara; Nobuyuki Asai; Yuji Hirano; Masatoshi Hayashi; Hiroyuki Miyake; Masayo Kojima; Naoki Ishiguro
RHEUMATOLOGY, 2015年01月, 査読有り, 招待無し
54(1), 113, 120, 10.1093/rheumatology/keu302

Comparison of efficacy and safety of tacrolimus and methotrexate in combination with abatacept in patients with rheumatoid arthritis; a retrospective observational study in the TBC Registry
Takayoshi Fujibayashi; Nobunori Takahashi; Daihei Kida; Atsushi Kaneko; Yuji Hirano; Naoki Fukaya; Yuichiro Yabe; Takeshi Oguchi; Seiji Tsuboi; Hiroyuki Miyake; Toki Takemoto; Masashi Kawasaki; Naoki Ishiguro; Toshihisa Kojima
MODERN RHEUMATOLOGY, 2015年, 査読有り, 招待無し
25(6), 825, 830, 10.3109/14397595.2015.1029238

Importance of methotrexate therapy concomitant with tocilizumab treatment in achieving better clinical outcomes for rheumatoid arthritis patients with high disease activity: An observational cohort study
Toshihisa Kojima; Yuichiro Yabe; Atsushi Kaneko; Nobunori Takahashi; Koji Funahashi; Daizo Kato; Masahiro Hanabayashi; Shuji Asai; Shinya Hirabara; Nobuyuki Asai; Yuji Hirano; Masatoshi Hayashi; Hiroyuki Miyake; Masayo Kojima; Naoki Ishiguro
Rheumatology (United Kingdom), 2014年11月, 査読無し, 招待無し
54(1), 113, 120, 10.1093/rheumatology/keu302

Clinical efficacy of abatacept, tocilizumab, and etanercept in Japanese rheumatoid arthritis patients with inadequate response to anti-TNF monoclonal antibodies
Shinya Hirabara; Nobunori Takahashi; Naoki Fukaya; Hiroyuki Miyake; Yuichiro Yabe; Atsushi Kaneko; Takayasu Ito; Takeshi Oguchi; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Fumiaki Sugiura; Masatoshi Hayashi; Koji Funahashi; Masahiro Hanabayashi; Shuji Asai; Naoki Ishiguro; Toshihisa Kojima
CLINICAL RHEUMATOLOGY, 2014年09月, 査読有り, 招待無し
33(9), 1247, 1254, 10.1007/s10067-014-2711-2

Longterm Retention Rate and Risk Factor for Discontinuation Due to Insufficient Efficacy and Adverse Events in Japanese Patients with Rheumatoid Arthritis Receiving Etanercept Therapy
Hiroyuki Matsubara; Toshihisa Kojima; Atsushi Kaneko; Yuji Hirano; Hisato Ishikawa; Yousuke Hattori; Hiroyuki Miyake; Takeshi Oguchi; Hideki Takagi; Yuichiro Yabe; Takefumi Kato; Takayasu Ito; Naoki Fukaya; Yasuhide Kanayama; Tomone Shioura; Masatoshi Hayashi; Takayoshi Fujibayashi; Nobunori Takahashi; Koji Funahashi; Daizo Kato; Masahiro Hanabayashi; Kenya Terabe; Naoki Ishiguro
JOURNAL OF RHEUMATOLOGY, 2014年08月, 査読有り, 招待無し
41(8), 1583, 1589, 10.3899/jrheum.130901

Alexithymia, Depression, Inflammation, and Pain in Patients With Rheumatoid Arthritis
Masayo Kojima; Toshihisa Kojima; Sadao Suzuki; Nobunori Takahashi; Koji Funahashi; Daizo Kato; Masahiro Hanabayashi; Shinya Hirabara; Shuji Asai; Naoki Ishiguro
ARTHRITIS CARE & RESEARCH, 2014年05月, 査読有り, 招待無し
66(5), 679, 686, 10.1002/acr.22203

Clinical efficacy of abatacept compared to adalimumab and tocilizumab in rheumatoid arthritis patients with high disease activity
Nobunori Takahashi; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Takefumi Kato; Naoki Fukaya; Hisato Ishikawa; Masatoshi Hayashi; Seiji Tsuboi; Yasuhide Kanayama; Daizo Kato; Koji Funahashi; Hiroyuki Matsubara; Yosuke Hattori; Masahiro Hanabayashi; Shinya Hirabara; Kenya Terabe; Yutaka Yoshioka; Naoki Ishiguro
CLINICAL RHEUMATOLOGY, 2014年01月, 査読有り, 招待無し
33(1), 39, 47, 10.1007/s10067-013-2392-2

Monitoring C-reactive protein levels to predict favourable clinical outcomes from tocilizumab treatment in patients with rheumatoid arthritis
Toshihisa Kojima; Yuichiro Yabe; Atsushi Kaneko; Yuji Hirano; Hisato Ishikawa; Masatoshi Hayashi; Hiroyuki Miyake; Hideki Takagi; Takefumi Kato; Kenya Terabe; Tsuyoshi Wanatabe; Hiroki Tsuchiya; Daihei Kida; Tomone Shioura; Koji Funahashi; Daizo Kato; Hiroyuki Matsubara; Nobunori Takahashi; Yosuke Hattori; Nobuyuki Asai; Naoki Ishiguro
Modern Rheumatology, 2013年09月, 査読有り, 招待無し
23(5), 977, 985, 10.1007/s10165-012-0782-y

Clinical efficacy of abatacept in Japanese rheumatoid arthritis patients
Nobunori Takahashi; Toshihisa Kojima; Kenya Terabe; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Hideki Takagi; Takeshi Oguchi; Hiroyuki Miyake; Takefumi Kato; Naoki Fukaya; Hisato Ishikawa; Masatoshi Hayashi; Seiji Tsuboi; Daizo Kato; Koji Funahashi; Hiroyuki Matsubara; Yosuke Hattori; Masahiro Hanabayashi; Shinya Hirabara; Yutaka Yoshioka; Naoki Ishiguro
MODERN RHEUMATOLOGY, 2013年09月, 査読有り, 招待無し
23(5), 904, 912, 10.1007/s10165-012-0760-4

Hyaluronan inhibits TLR-4 dependent cathepsin K and matrix metalloproteinase 1 expression in human fibroblasts
Shinya Hirabara; Toshihisa Kojima; Nobunori Takahashi; Masahiro Hanabayashi; Naoki Ishiguro
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013年01月, 査読有り, 招待無し
430(2), 519, 522, 10.1016/j.bbrc.2012.12.003

関節リウマチ患者は薬物治療の変化をどのように感じているか フォーカスグループによる質的研究
小嶋雅代; 小嶋俊久; 難波大夫; 茂木七香; 大谷尚; 高橋伸典; 加藤大三; 舟橋康治; 松原 浩之; 服部 陽介; 石黒 直樹
中部リウマチ, 2013年, 査読無し, 招待無し
43(1), 17, 20

Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides
Wataru Ariyoshi; Nobunori Takahashi; Daisuke Hida; Cheryl B. Knudson; Warren Knudson
ARTHRITIS AND RHEUMATISM, 2012年01月, 査読有り, 招待無し
64(1), 187, 197, 10.1002/art.33329

Induction of CD44 Cleavage in Articular Chondrocytes
Nobunori Takahashi; Cheryl B. Knudson; Sai Thankamony; Wataru Ariyoshi; Liliana Mellor; Hee-Jeong Im; Warren Knudson
ARTHRITIS AND RHEUMATISM, 2010年05月, 査読有り, 招待無し
62(5), 1338, 1348, 10.1002/art.27410

Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways
I. Schmitz; W. Ariyoshi; N. Takahashi; C. B. Knudson; W. Knudson
OSTEOARTHRITIS AND CARTILAGE, 2010年03月, 査読有り, 招待無し
18(3), 447, 454, 10.1016/j.joca.2009.10.007

Hyaluronan promotes the chondrocyte response to BMP-7.
Andhare RA; Takahashi N; Knudson W; Knudson CB
Osteoarthritis Cartilage., 2009年07月, 査読有り, 招待無し
17(7), 906-16

Correlation between parathyroid hormone, bone alkaline phosphatase and N-telopeptide of type 1 collagen in diabetic and non-diabetic haemodialysis patients
Nobunori Takahashi; Toshihisa Kojima; Hiroshi Ogawa; Naoki Ishiguro
NEPHROLOGY, 2007年12月, 査読有り, 招待無し
12(6), 539, 545, 10.1111/j.1440-1797.2007.00829.x

Clinical effectiveness and long-term retention of abatacept in elderly rheumatoid arthritis patients: Results from a multicenter registry system.
Takahashi N; Kojima T; Kida D; Kaneko A; Hirano Y; Fujibayashi T; Yabe Y; Takagi H; Oguchi T; Hanabayashi M; Kato T; Funahashi K; Hayashi M; Tsuboi S; Kanayama Y; Sobue Y; Asai N; Matsumoto T; Watanabe T; Asai S; Ishiguro N
Modern rheumatology, 2018年09月15日, 査読無し, 招待無し
1-23, 10.1080/14397595.2018.1525019

An Open-Label, Single-Arm Study of a Patient-Specific Femoral Guide for Total Hip Arthroplasty via the Anterolateral Supine Approach, Linked with Three-Dimensional Surgical Support Software: Study Protocol.
Kida D; Hashimoto H; Ito N; Kito Y; Mori K; Takahashi N; Tomita Y
The Kurume medical journal, 2018年09月10日, 査読無し, 招待無し
65(2), 71, 75, 10.2739/kurumemedj.MS652002

Influence of methotrexate on gastrointestinal symptoms in patients with rheumatoid arthritis.
Asai S; Nagai K; Takahashi N; Watanabe T; Matsumoto T; Asai N; Sobue Y; Ishiguro N; Kojima T
International journal of rheumatic diseases, 2018年08月30日, 査読無し, 招待無し
10.1111/1756-185X.13380

An Open-label Single-arm Trial of a Novel Extramedullary Guide Coordinated with 3D Surgical Assistive Software for Total Knee Arthroplasty.
Kida D; Hashimoto H; Saito AM; Kito Y; Mori K; Terabe K; Takahashi N; Tomita Y
Acta medica Okayama, 2018年08月, 査読無し, 招待無し
72(4), 441-445, 10.18926/AMO/56186

Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study
Shuji Asai; Takayoshi Fujibayashi; Takeshi Oguchi; Masahiro Hanabayashi; Masatoshi Hayashi; Hiroyuki Matsubara; Takayasu Ito; Yuichiro Yabe; Tsuyoshi Watanabe; Yuji Hirano; Yasuhide Kanayama; Atsushi Kaneko; Takefumi Kato; Hideki Takagi; Nobunori Takahashi; Koji Funahashi; Toki Takemoto; Nobuyuki Asai; Tatsuo Watanabe; Naoki Ishiguro; Toshihisa Kojima
Modern Rheumatology, 2018年03月04日, 査読無し, 招待無し
28(2), 221, 226, 10.1080/14397595.2017.1332558

High rate of improvement in serum matrix metalloproteinase-3 levels at 4 weeks predicts remission at 52 weeks in RA patients treated with adalimumab
Yosuke Hattori; Toshihisa Kojima; Atsushi Kaneko; Daihei Kida; Yuji Hirano; Takayoshi Fujibayashi; Yuichiro Yabe; Takeshi Oguchi; Yasuhide Kanayama; Hiroyuki Miyake; Takefumi Kato; Hideki Takagi; Masatoshi Hayashi; Takayasu Ito; Tomone Shioura; Nobunori Takahashi; Hisato Ishikawa; Koji Funahashi; Naoki Ishiguro
Modern Rheumatology, 2018年01月02日, 査読無し, 招待無し
28(1), 119, 125, 10.1080/14397595.2017.1317320

The Predictors for 24 Months Efficacy of Denosumab, an Anti-RANKL Antibody, on Osteoporosis in Rheumatoid Arthritis Patients from Japanese Multicenter Study (TBCRBONE).
Hirano Yuji; Kanayama Yasuhide; Hattori Kyosuke; Takahashi Nobunori; Ishiguro Naoki; Kojima Toshihisa
JOURNAL OF BONE AND MINERAL RESEARCH, 2017年12月, 査読無し, 招待無し
32, S159-S159

Influence of glucocorticoids on effect of denosumab on osteoporosis in patients with Japanese rheumatoid arthritis; 24 months of follow-up similar to a Multicenter Registry Study similar to.
Kanayama Yasuhide; Hirano Yuji; Takahashi Nobunori; Asai Shuji; Ishiguro Naoki; Kojima Toshihisa
JOURNAL OF BONE AND MINERAL RESEARCH, 2017年12月, 査読無し, 招待無し
32, S379-S380

The Predictors of the Efficacy of Denosumab, a Monoclonal Antibody to RANK Ligand, on Osteoporosis in Rheumatoid Arthritis Patients from Japanese Multicenter Study
Hattori Kyosuke; Hirano Yuji; Kanayama Yasuhide; Takahashi Nobunori; Ishiguro Naoki; Kojima Toshihisa
ARTHRITIS & RHEUMATOLOGY, 2017年10月, 査読無し, 招待無し
69, .

Being Elderly Is Not a Predictive Factor of Discontinuation of Abatacept Due to Adverse Events in Rheumatoid Arthritis Patients with Concomitant Methotrexate: A Retrospective Observational Study Based on Data from a Japanese Multicenter Registry Study
Takahashi Nobunori; Kojima Toshihisa; Asai Shuji; Watanabe Tatsuo; Matsumoto Takuya; Asai Nobuyuki; Sobue Yasumori; Ishiguro Naoki
ARTHRITIS & RHEUMATOLOGY, 2017年10月, 査読無し, 招待無し
69, .

Association between Methotrexate Use and Effects of Treatment with a Second Biologic Agent in Rheumatoid Arthritis: A Multiple Imputation Approach
Ogawa Yoshikazu; Takahashi Nobunori; Ishiguro Naoki; Kojima Toshihisa
ARTHRITIS & RHEUMATOLOGY, 2017年10月, 査読無し, 招待無し
69, .

Patient-reported outcomes as assessment tools and predictors of long-term prognosis: a 7-year follow-up study of patients with rheumatoid arthritis
Masayo Kojima; Toshihisa Kojima; Sadao Suzuki; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Yutaka Yoshioka; Kenya Terabe; Nobuyuki Asai; Toki Takemoto; Naoki Ishiguro
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 2017年09月, 査読無し, 招待無し
20(9), 1193, 1200, 10.1111/1756-185X.12789

Two cases of autoimmune pulmonary alveolar proteinosis with rheumatoid arthritis
Satoru Ito; Keiko Wakahara; Toshihisa Kojima; Nobunori Takahashi; Kimitoshi Nishiwaki; Etsuro Yamaguchi; Yoshinori Hasegawa
ALLERGOLOGY INTERNATIONAL, 2017年07月, 査読無し, 招待無し
66(3), 507, 509, 10.1016/j.alit.2017.02.002

THE PREDICTORS FOR 24 MONTHS EFFICACY OF DENOSUMAB, AN ANTI-RANKL ANTIBODY, ON OSTEOPOROSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS FROM MULTICENTER STUDY (TBCR-BONE)
Y. Hirano; Y. Kanayama; N. Takahashi; N. Ishiguro; T. Kojima
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 1357, 1357, 10.1136/annrheumdis-2017-eular.3938

TENDENCY TO CHOOSE FIRST BIOLOGIC AGENT THERAPY OF RHEUMATOID ARTHRITIS IN THE ELDERLY: RESULTS FROM JAPANESE MULTICENTER REGISTRY
T. Watanabe; T. Kojima; N. Takahashi; S. Asai; N. Asai; T. Matsumoto; Y. Sobue; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 1195, 1195, 10.1136/annrheumdis-2017-eular.1679

RELATIONSHIP BETWEEN RHEUMATOID FACTOR POSITIVITY AND TREATMENT EFFECT WITH A FIRST BIOLOGIC AGENT IN RHEUMATOID ARTHRITIS: MULTICENTER STUDY USING A MIXED-EFFECT MODEL
Y. Ogawa; N. Takahashi; N. Ishiguro; T. Kojima
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 799, 799, 10.1136/annrheumdis-2017-eular.1508

INFLUENCE OF ORAL PREDNISOLONE ON EFFECT OF DENOSUMAB ON OSTEOPOROSIS IN PATIENTS WITH JAPANESE RHEUMATOID ARTHRITIS; 24 MONTHS OF FOLLOW-UP similar to A MULTICENTER REGISTRY STUDY similar to
Y. Kanayama; Y. Hirano; N. Takahashi; S. Asai; N. Ishiguro; T. Kojima
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 708, 708, 10.1136/annrheumdis-2017-eular.4677

EFFICACY OF TOCILIZUMAB FOR SUPPRESSING RADIOGRAPHIC PROGRESSION OF CERVICAL LESIONS IN PATIENTS WITH RHEUMATOID ARTHRITIS COMPARISON WITH METHOTREXATE TREATMENT; TWO YEARS OF FOLLOW-UP similar to A MULTICENTER REGISTRY STUDY similar to
Y. Kanayama; T. Kojima; Y. Hirano; Y. Yabe; N. Takahashi; Y. Oishi; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 582, 582, 10.1136/annrheumdis-2017-eular.4698

USE OF A 8-WEEK OBSERVATIONAL PERIOD FOR PREDICTING REMISSION AND LOW DISEASE ACTIVITY AT 52 WEEKS IN RA PATIENTS TREATED WITH CERTOLIZUMAB PEGOL - A MULTICENTER STUDY
Y. Kanayama; A. Kaneko; N. Takahashi; T. Kato; M. Hayashi; Y. Hattori; N. Asai; N. Ishiguro; T. Kojima
ANNALS OF THE RHEUMATIC DISEASES, 2017年06月, 査読無し, 招待無し
76, 835, 836, 10.1136/annrheumdis-2017-eular.4653

Association Between Rheumatoid Factor Positivity and Effects of Treatment with a First Biologic Agent in Rheumatoid Arthritis
Yoshikazu Ogawa; Nobunori Takahashi; Toshihisa Kojima; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2016年10月, 査読無し, 招待無し
68

Association Between Methotrexate Use and Effects of Treatment with a Second Biologic Agent in Rheumatoid Arthritis
Yoshikazu Ogawa; Nobunori Takahashi; Toshihisa Kojima; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2016年10月, 査読無し, 招待無し
68

Sero-Positivity for Rheumatoid Factor Is an Independent Predictor for Achievement of Good EULAR Response at 24 Weeks in ACPA Positive Rheumatoid Arthritis Patients Treated with Abatacept: Results from Japanese Multicenter Registry
Nobunori Takahashi; Toshihisa Kojima; Shuji Asai; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2016年10月, 査読無し, 招待無し
68

Predictive Value of Chest HRCT Patterns for Respiratory Adverse Event Among RA Patients Treated with Biological Therapy: Long-Term Results from an Observational Study
Takuya Matsumoto; Toshihisa Kojima; Nobunori Takahashi; Shuji Asai; Nobuyuki Asai; Tatsuo Watanabe; Tomonori Kobayakawa; Naoki Ishiguro; Shingo Iwano; Satoru Ito
ARTHRITIS & RHEUMATOLOGY, 2016年10月, 査読無し, 招待無し
68

INFLUENCE OF ORAL PREDNISOLONE ON EFFECT OF DENOSUMAB ON OSTEOPOROSIS IN PATIENTS WITH JAPANESE RHEUMATOID ARTHRITIS; 12 MONTHS OF FOLLOW-UP - A MULTICENTER REGISTRY STUDY
Y. Kanayama; Y. Hirano; N. Takahashi; S. Asai; N. Ishiguro; T. Kojima
ANNALS OF THE RHEUMATIC DISEASES, 2016年06月, 査読無し, 招待無し
75, 358, 358, 10.1136/annrheumdis-2016-eular.2827

RETENTION RATE OF BIOLOGIC AGENTS AFTER REMISSION INDUCED WITH AND WITHOUT CONCOMITANT GLUCOCORTICOID TREATMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS: A PROPENSITY SCORE MATCHED ANALYSIS
S. Asai; T. Kojima; N. Takahashi; K. Funahashi; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2016年06月, 査読無し, 招待無し
75, 260, 261, 10.1136/annrheumdis-2016-eular.1639

Rheumatoid Factor Status Affects the Efficacy of First Biological Treatment in RA
Yoshikazu Ogawa; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Toki Takemoto; Tatsuo Watanabe; Nobuyuki Asai; Naoki Ishiguro; Toshihisa Kojima
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Drug Retention Rates of Biologic Monotherapies for Patients with Rheumatoid Arthritis Receiving TNF Inhibiting Fusion Protein Agent and Antibody Agent; From Multicenter Registry in Japan
Hiroyuki Matsubara; Masatoshi Hayashi; Nobunori Takahashi; Toshihisa Kojima; Koji Funahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Siglec9 Suppresses Arthritis in Collagen-Induced Mice Model and Inhibits M1 Activation of RAW264.7 Macrophages
Takuya Matsumoto; Nobunori Takahashi; Toshihisa Kojima; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Head-to-Head Comparison of the Retention Rate of First Biologics in Elderly Patients with Rheumatoid Arthritis in Japanese Clinical Practice: Results from the Multicenter Biologic Registry
Masatoshi Hayashi; Toshihisa Kanamono; Hiroyuki Matsubara; Toshihisa Kojima; Koji Funahashi; Nobunori Takahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Predictive Factors for Achieving Low Disease Activity at 52 Weeks after Switching from Tumor Necrosis Factor Inhibitors to Abatacept: Results from a Multicenter Observational Cohort Study of Japanese Patients
Toshihisa Kojima; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Toki Takemoto; Nobuyuki Asai; Tatsuo Watanabe; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Long-Term Retention Rate of First Biologics in Patients of Age over 75 Years with Rheumatoid Arthritis in Japanese Clinical Practice: Results from the Multicenter Biologic Registry
Masatoshi Hayashi; Toshihisa Kanamono; Hiroyuki Matsubara; Toshihisa Kojima; Koji Funahashi; Nobunori Takahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Positivity for Rheumatoid Factor Is Associated with a Better Short-Term Response and Long-Term Drug Retention of Abatacept: Results from Consecutive 508 Patients with Rheumatoid Arthritis in a Japanese Multicenter Registry
Nobunori Takahashi; Toshihisa Kojima; Koji Funahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

Titer of Anti-Citrullinated Peptide Antibody Affects the Efficacy of First Biological Treatment in Rheumatoid Arthritis
Yoshikazu Ogawa; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Toki Takemoto; Tatsuo Watanabe; Nobuyuki Asai; Naoki Ishiguro; Toshihisa Kojima
ARTHRITIS & RHEUMATOLOGY, 2015年10月, 査読無し, 招待無し
67

THE IMPACT OF PHYSICAL FUNCTION ON PATIENT GLOBAL ASSESSMENT IN RHEUMATOID ARTHRITIS
T. Watanabe; T. Kojima; N. Takahashi; K. Funahashi; S. Asai; T. Takemoto; N. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2015年06月, 査読無し, 招待無し
74, 1297, 1298, 10.1136/annrheumdis-2015-eular.2018

Effect and Safety of Concomitant Methotrexate and Tacrolimus on Clinical Response of Abatacept in Rheumatoid Arthritis Patients with Prior Use of Biological Dmards.
Nobunori Takahashi; Toshihisa Kojima; Yuji Hirano; Yasuhide Kanayama; Koji Funahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S222, S223

Clinical Efficacy of Add-on Iguratimod Therapy in Patients with Active Rheumatoid Arthritis Despite of Methotrexate similar to a Multicenter Registry Study similar to
Yasuhide Kanayama; Toshihisa Kojima; Atsushi Kaneko; Yuji Hirano; Nobunori Takahashi; Shinya Hirabara; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S655, S655

The Safety and Treatment Efficacy of Abatacept in Rheumatoid Arthritis Patients with Pulmonary Complications: From the Tsurumai Biologics Communication Registry (TBCR) Multicenter Study.
Shinya Hirabara; Toshihisa Kojima; Nobunori Takahashi; Yuji Hirano; Atsushi Kaneko; Daihei Kida; Yasuhide Kanayama; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S224, S225

Improving of Safety in Treatment with Biologics during First Seven-Years Experiences; Long-Term Results from Observational Cohort Study of Clinical Practice Using Multicenter Registry in Japan
Toshihisa Kojima; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Yutaka Yoshioka; Kenya Terabe; Nobuyuki Asai; Toki Takemoto; Naoki Ishiguro; Atsushi Kaneko; Yuji Hirano; Yuichiro Yabe; Yasuhide Kanayama
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S202, S203

Influences of Disease Activity at the Initiation of Iguratimod, a Small Molecule Antirheumatic Drug, on Efficacy of Iguratimod in Patients with Rheumatoid Arthritis -a Multicenter Registry Study-
Yuji Hirano; Toshihisa Kojima; Yasuhide Kanayama; Shinya Hirabara; Nobunori Takahashi; Atsushi Kaneko; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S655, S656

Reasons and Risk Factor for Discontinuation of Biologic Agents in Rheumatoid Arthritis Patients
Kenya Terabe; Toshihisa Kojima; Nobunori Takahashi; Koji Funahashi; Atsushi Kaneko; Yuji Hirano; Yasuhide Kanayama; Yuichiro Yabe; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S1099, S1100

Impact of Concomitant Methotrexate on the Enhanced Clinical Efficacy of Abatacept after 24 Weeks in Rheumatoid Arthritis Patients
Nobunori Takahashi; Toshihisa Kojima; Yuji Hirano; Yasuhide Kanayama; Koji Funahashi; Naoki Ishiguro
ARTHRITIS & RHEUMATOLOGY, 2014年10月, 査読無し, 招待無し
66, S1094, S1095

CONCOMITANT METHOTREXATE DID NOT AFFECT DISCONTINUATION RATE OF ETANERCEPT DUE TO INEFFECTIVENESS: SIX-YEAR RESULTS FROM JAPANESE MULTICENTER REGISTRY SYSTEM
N. Takahashi; T. Kojima; K. Funahashi; M. Hanabayashi; S. Hirabara; S. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 940, 941, 10.1136/annrheumdis-2014-eular.1422

LONG-TERM OUTCOME OF INFLIXIMAB THERAPY IN RHEUMATOID ARTHRITIS PATIENTS -RESULTS FROM JAPANESE MULTICENTER REGISTRY SYSTEM-
N. Takahashi; T. Kojima; K. Funahashi; M. Hanabayashi; S. Hirabara; S. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 477, 477, 10.1136/annrheumdis-2014-eular.1420

CONSIDERING THE MAINTENANCE TREATMENT WITH TOCILIZUMAB FOR RHEUMATOID ARTHRITIS, WE HAD BETTER TREAT IN COMBINATION WITH MTX. THE REPORT OF 2YEARS MULTI-CENTER CLINICAL PRACTICE
K. Funahashi; T. Kojima; N. Takahashi; M. Hanabayashi; S. Hirabara; S. Asai; Y. Yoshioka; Y. Yabe; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 507, 507, 10.1136/annrheumdis-2014-eular.3231

THE RELATIONSHIP BETWEEN DISEASE ACTIVITY, DISEASE DURATION, PATIENT GLOBAL ASSESSMENT, AND PHYSICAL FUNCTION IN RHEUMATOID ARTHRITIS
T. Watanabe; T. Kojima; N. Takahashi; K. Funahashi; M. Hanabayashi; S. Hirabara; S. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 1168, 1169, 10.1136/annrheumdis-2014-eular.2079

IMPACT OF CONCOMITANT METHOTREXATE ON THE ENHANCED CLINICAL EFFICACY OF ABATACEPT AFTER 24 WEEKS IN RHEUMATOID ARTHRITIS PATIENTS
N. Takahashi; T. Kojima; K. Funahashi; M. Hanabayashi; S. Hirabara; S. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 680, 680, 10.1136/annrheumdis-2014-eular.2346

IMPORTANCE OF CONCOMITANT METHOTREXATE WITH TOCILIZUMAB AND ASSESSMENT OF STRUCTUAL DAMAGE FOR ACHIEVING BETTER CLINICAL OUTCOMES FOR RHEUMATOID ARTHRITIS PATIENTS WITH HIGH DISEASE ACTIVITY: AN OBSERVATIONAL COHORT STUDY
T. Kojima; N. Takahashi; K. Funahashi; S. Asai; S. Hirabara; M. Hanabayashi; Y. Yoshioka; Y. Yabe; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 612, 612, 10.1136/annrheumdis-2014-eular.1710

THE CLINICAL EFFICACY AND SAFETY OF ABATACEPT FOR RHEUMATOID ARTHRITIS FROM JAPANESE MULTI-CENTER REGISTRY: 2-YEAR OUTCOMES
M. Hanabayashi; T. Kojima; N. Takahashi; D. Kida; K. Funahashi; S. Hirabara; S. Asai; Y. Yoshioka; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 677, 677, 10.1136/annrheumdis-2014-eular.2078

TWELVE WEEKS IS LONG ENOUGH TO PREDICT LOW DISEASE ACTIVITY AT 52 WEEKS IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH ABATACEPT
N. Takahashi; T. Kojima; K. Funahashi; M. Hanabayashi; S. Hirabara; S. Asai; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2014年06月, 査読無し, 招待無し
73, 954, 954, 10.1136/annrheumdis-2014-eular.2349

Relationship Between physicians' Decision To Use Concomitant Glucocorticoid and Remission During Treatment With Tocilizumab In Patients With Background Of Limited Dose Of MTX
Toshihisa Kojima; Nobunori Takahashi; Koji Funahashi; Shuji Asai; Masahiro Hanabayashi; Shinya Hirabara; Nobuyuki Asai; Naoki Ishiguro
ARTHRITIS AND RHEUMATISM, 2013年10月, 査読無し, 招待無し
65, S629, S629

Concomitant Methotrexate Did Not Affect Discontinuation Rate Of Etanercept Due To Ineffectiveness: Six-Year Results From Japanese Multicenter Registry System
Nobunori Takahashi; Toshihisa Kojima; Atsushi Kaneko; Yuji Hirano; Naoki Ishiguro
ARTHRITIS AND RHEUMATISM, 2013年10月, 査読無し, 招待無し
65, S1011, S1011

RISK FACTORS FOR PROGRESSION OF LARGE JOINT DESTRUCTION IN PATIENTS WITH RHEUMATOID ARTHRITIS BASED ON INCIDENT RATE OF JOINT SURGERY DURING TREATMENT WITH BIOLOGICS
S. Asai; T. Kojima; N. Takahashi; K. Funahashi; D. Katoh; Y. Hattori; M. Hanabayashi; K. Terabe; N. Ishiguro
ANNALS OF THE RHEUMATIC DISEASES, 2013年06月, 査読無し, 招待無し
72, 583, 583

Monitoring C-reactive protein levels to predict favourable clinical outcomes from tocilizumab treatment in patients with rheumatoid arthritis.
Kojima T; Yabe Y; Kaneko A; Hirano Y; Ishikawa H; Hayashi M; Miyake H; Takagi H; Kato T; Terabe K; Wanatabe T; Tsuchiya H; Kida D; Shioura T; Funahashi K; Kato D; Matsubara H; Takahashi N; Hattori Y; Asai N; Ishiguro N
Mod Rheumatol., 2012年, 査読有り, 招待無し
ahead of print

Clinical efficacy of abatacept in Japanese rheumatoid arthritis patients.
Takahashi N; Kojima T; Terabe K; Kaneko A; Kida D; Hirano Y; Fujibayashi T; Yabe Y; Takagi H; Oguchi T; Miyake H; Kato T; Fukaya N; Ishikawa H; Hayashi M; Tsuboi S; Kato D; Funahashi K; Matsubara H; Hattori Y; Hanabayashi M; Hirabara S; Yoshioka Y; Ishiguro N
Mod Rheumatol., 2012年, 査読有り, 招待無し
ahead of print

Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides.
Ariyoshi W; Takahashi N; Hida D; Knudson CB; Knudson W
Arthritis Rheum., 2011年, 査読有り, 招待無し
ahead of print

Induction of CD44 cleavage in articular chondrocytes.
Takahashi N; Knudson CB; Thankamony S; Ariyoshi W; Mellor L; Im HJ; Knudson W
Arthritis Rheum., 2010年05月, 査読有り, 招待無し
62(5), 1338-48

Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways.
Schmitz I; Ariyoshi W; Takahashi N; Knudson CB; Knudson W
Osteoarthritis Cartilage., 2010年03月, 査読有り, 招待無し
18(3), 447-54

Hyaluronan promotes the chondrocyte response to BMP-7.
Andhare RA; Takahashi N; Knudson W; Knudson CB
Osteoarthritis Cartilage., 2009年07月, 査読有り, 招待無し
17(7), 906-16

Correlation between parathyroid hormone, bone alkaline phosphatase and N-telopeptide of type 1 collagen in diabetic and non-diabetic haemodialysis patients.
Takahashi N; Kojima T; Ogawa H; Ishiguro N
Nephrology (Carlton), 2007年12月, 査読有り, 招待無し
12(6), 539-45

ヒアルロン酸とCD44
高橋伸典
第26回日本整形外科学会基礎学術集会, 2011年, 招待無し
シンポジウム・ワークショップパネル（公募）, 国際会議

生物学的製剤使用中に 悪性リンパ腫を併発した関節 リウマチ患者４例における検討
高橋伸典; 金子敦史; 来田大平; 佐藤智太郎; 小嶋俊久; 石黒直樹
第23回中部リウマチ学会, 2011年, 招待無し
口頭発表（一般）, 国際会議

インフリキシマブ増量プロトコール導入後の治療成績
高橋伸典; 齋藤究; 金子敦史; 来田大平; 佐藤智太郎
第55回日本リウマチ学会, 2011年, 招待無し
口頭発表（一般）, 国際会議

Superficial zone chondrocytes from bovine articular cartilage respond predominately to exogenous BMP-7
N. Takahashi; W. Ariyoshi; W. Knudson; C.B. Knudson
57th Annual Meeting of Orthopaedic Research Society, 2011年, 招待無し
その他, 国内会議

牛関節軟骨細胞において表層部細胞は、中間部/深部細胞と比較して強いBMP-7への反応性を示す
高橋 伸典; 有吉 渉; Cheryl B Knudson; Warren Knudson
第24回日本軟骨代謝学会, 2011年, 招待無し
口頭発表（一般）, 国際会議

CRP・血沈陰性の関節リウマチ患者において、血清MMP-3が高値を示す因子についての検討
高橋伸典; 金子敦史; 来田太平; 斉藤究; 佐藤智太郎; 衛藤義人
第83回日本整形外科学会, 2010年, 招待無し
口頭発表（一般）, 国際会議

生物学的製剤導入後における MMP-3値の変動についての検討
高橋伸典; 金子敦史; 来田大平; 斎藤 究; 佐藤智太郎; 衛藤義人
第54回日本リウマチ学会, 2010年, 招待無し
口頭発表（一般）, 国際会議

MMP-3高値を示す、CRP・血沈陰性の 関節リウマチ患者についての検討
高橋伸典; 金子敦史; 斉藤究; 来田大平; 佐藤智太郎; 衛藤義人
第54回日本リウマチ学会, 2010年, 招待無し
口頭発表（一般）, 国際会議

Hyaluronan oligosaccharides induce MMP-3 via transcriptional activation of NF-κB in articular chondrocytes
Takahashi, N; Knudson, CB; Ariyoshi, W; Knudson, W
56th Annual Meeting of Orthopaedic Research Society, 2010年, 招待無し
ポスター発表, 国内会議

Hyaluronan oligosaccharides induce BMP-7 via transcriptional activation of NF-κB and p38 MAP kinase in articular chondrocytes
Takahashi, N; Knudson, CB; Ariyoshi, W; Knudson, W
56th Annual Meeting of Orthopaedic Research Society, 2010年, 招待無し
ポスター発表, 国内会議

Hyaluronan oligosaccharides induce MMP-3 via transcriptional activation of NF-κB in articular chondrocytes
Takahashi, N; Knudson, CB; Ariyoshi, W; Knudson, W
56th Annual Meeting of Orthopaedic Research Society, 2010年, 招待無し
ポスター発表, 国内会議

Hyaluronan oligosaccharides induce BMP-7 via transcriptional activation of NF-κB and p38 MAP kinase in articular chondrocytes
Takahashi, N; Knudson, CB; Ariyoshi, W; Knudson, W
56th Annual Meeting of Orthopaedic Research Society, 2010年, 招待無し
ポスター発表, 国内会議

CRP・血沈陰性例において、MMP-3が高値を示す因子についての検討
高橋伸典; 金子敦史; 来田太平; 斉藤究; 佐藤智太郎; 衛藤義人
第23回日本臨床リウマチ学会, 2009年, 招待無し
口頭発表（一般）, 国際会議

Chondrocytes exhibit proteolytic fragmentation of CD44
Takahashi, N; Knudson, C; Ariyoshi, W; Knudson, W
第22回日本軟骨代謝学会, 2009年, 招待無し
シンポジウム・ワークショップパネル（公募）, 国際会議

De-differentiation of chondrocytes induces cleavage of CD44
Takahashi, N; Knudson, CB; Ariyoshi, W; Sampen, I; Knudson, W
55th Annual Meeting of Orthopaedic Research Society, 2009年, 招待無し
ポスター発表, 国内会議

Reversible De-differentiation alters BMP-7 Responsiveness
Nobunori Takahashi; Warren Knudson; Liliana Mellor; Cheryl B. Knudson
Gordon Research Conference, Musculoskeletal Biology, 2008年, 招待無し
ポスター発表, 国内会議

Disruption of Hyaluronan – CD44 Interactions Activates Phosphatidylinositol-3 Kinase Pathway in Chondrocytes
Takahashi, N; Schmitz, I; Knudson, W
54th Annual Meeting of Orthopaedic Research Society, 2008年, 招待無し
ポスター発表, 国内会議

CORRELATION BETWEEN PARATHYROID HORMONE, BONE ALKALINE PHOSPHATASE, AND N-TELOPEPTIDE OF TYPE I COLLAGEN IN DIABETIC PATIENTS ON REGULAR HEMODIALYSIS, COMPARED TO NON-DIABETIC PATIENTS
Takahashi, N; Kojima, T; Ishiguro, N
53th Annual Meeting of Orthopaedic Research Society, 2007年, 招待無し
ポスター発表, 国内会議

Nuclear factor-k decoy inhibits aggrecanase expressions in synovial cells derived from rheumatoid arthritis
Nobunori Takahashi; Toshihisa Kojima; Naoki Ishiguro
52th Annual Meeting of Orthopaedic Research Society, 2006年03月, 招待無し
ポスター発表, 国内会議

Cartilage metabolism in hemodialysis patients
Nobunori Takahashi; Toshihisa Kojima; Hiroshi Ogawa; Naoki Ishiguro
52th Annual Meeting of Orthopaedic Research Society, 2006年03月, 招待無し
ポスター発表, 国内会議

CARTILAGE METABOLISM IN HEMODIALYSIS PATIENTS ~by measuring degradation products resulting from the cleavage of type II collagen by collagenase~
Nobunori Takahashi; Toshihisa Kojima; Hiroshi Ogawa; Naoki Ishiguro
International Meeting of Glyco Matrix, 2006年, 招待無し
ポスター発表, 国内会議

血液透析患者における人工股関節置換術の成績
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第17回中部リウマチ学会, 2005年09月, 招待無し
口頭発表（一般）, 国際会議

透析患者における軟骨代謝 ～軟骨代謝マーカーＣ２Ｃを用いて～
高橋伸典; 小嶋俊久; 石黒直樹
第49回日本リウマチ学会, 2005年04月, 招待無し
口頭発表（一般）, 国際会議

透析患者における軟骨代謝：軟骨代謝マーカーC2Cを用いて
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第18回日本軟骨代謝学会, 2005年03月, 招待無し
口頭発表（一般）, 国際会議

Mortality and Morbidity after Hip Arthroplasty in Hemodialysis Patients
Nobunori Takahashi; Toshihisa Kojima; Hiroshi Ogawa; Naoki Ishiguro
Annual Scientific Meeting of American College of Rheumatology, 2005年, 招待無し
ポスター発表, 国内会議

透析患者のアミロイド関節症における軟骨代謝評価 ～特異的軟骨代謝マーカーC2Cを用いて～
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第50回日本透析医学会, 2005年, 招待無し
シンポジウム・ワークショップパネル（公募）, 国際会議

透析患者のアミロイド関節症における軟骨代謝評価 ～特異的軟骨代謝マーカーC2Cを用いて～
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第50回日本透析医学会, 2005年, 招待無し
シンポジウム・ワークショップパネル（公募）, 国際会議

Bone metabolism in hemodialysis patients
Nobunori Takahashi; Toshihisa Kojima; Hiroshi Ogawa; Naoki Ishiguro
51th Annual Meeting of Orthopaedic Research Society, 2005年, 招待無し
その他, 国内会議

骨代謝マーカーよりみた血液透析患者における副甲状腺ホルモンと骨芽細胞・破骨細胞機能の関連
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第19回日本整形外科学会基礎学術集会, 2004年10月, 招待無し
口頭発表（一般）, 国際会議

血液透析患者における人工股関節置換術
高橋伸典; 小嶋俊久; 石黒直樹; 小川洋史
第77回日本整形外科学会学術集会, 2004年05月, 招待無し
口頭発表（一般）, 国際会議

長期血液透析患者における人工股関節置換術の成績
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第48回日本リウマチ学会, 2004年04月, 招待無し
口頭発表（一般）, 国際会議

血液透析期間と血清中骨代謝マーカー変化の関連について
高橋伸典; 小嶋俊久; 小川洋史; 石黒直樹
第49回日本透析医学会, 2004年, 招待無し
口頭発表（一般）, 国際会議

長期透析患者において、人工股関節再置換術を行った5症例の経験
高橋伸典; 小嶋俊久; 石黒直樹
第18回日本臨床リウマチ学会, 2003年10月, 招待無し
口頭発表（一般）, 国際会議

25年以上の長期血液透析患者におけるアミロイド性股関節症に対して手術的治療を行った３例
高橋伸典; 小嶋俊久; 石黒直樹
第15回中部リウマチ学会, 2003年09月, 招待無し
口頭発表（一般）, 国際会議

椎弓形成術後にアライメント増悪を起こした頚椎破壊性脊椎関節症（DSA）の１例
高橋伸典; 松山幸弘; 吉原永武; 中村博司; 石黒直樹
第48回日本透析医学会, 2003年06月, 招待無し
口頭発表（一般）, 国際会議

椎弓形成術後にアライメント増悪を起こした頚椎破壊性脊椎関節症（DSA）の１例
高橋伸典; 松山幸弘; 吉原永武; 中村博司; 石黒直樹; 小川洋史
第58回東海脊椎外科研究会, 2002年11月, 招待無し
口頭発表（一般）, 国際会議

Essex-Lopresti骨折の1例
高橋伸典; 浦田士郎; 渡部健; 鈴木和広; 田中健司; 大場満成; 加藤大三; 中島正二郎; 森本章夫; 古川了子
第182回整形外科集談会東海地方会, 2000年12月, 招待無し
口頭発表（一般）, 国際会議

開放性大腿骨頭骨折受傷14年後にTHAを行った1例
高橋伸典; 渡部健; 浦田士郎; 鈴木和広; 田中健司; 大場満成; 松木浩; 吉川圭子; 加藤大三; 中島正二郎; 森本章夫
第177回整形外科集談会東海地方会, 1999年09月, 招待無し
口頭発表（一般）, 国際会議

ヒアルロン酸レセプターCD44の断片化阻害による、関節軟骨変性抑制効果
基盤研究(C)
愛知医科大学
2023年04月01日 - 2026年03月31日
高橋 伸典; 寺部 健哉; 大橋 禎史, 高橋 伸典; 寺部 健哉; 大橋 禎史, 日本学術振興会, 日本学術振興会

活性値の乖離に着目した血友病性関節症の病態解明とアンメットニーズの開拓
基盤研究(C)
名古屋大学
2021年04月01日 - 2024年03月31日
鈴木 伸明; 高橋 伸典; 田村 彰吾; 鈴木 敦夫, 鈴木 伸明; 高橋 伸典; 田村 彰吾; 鈴木 敦夫, 日本学術振興会, 日本学術振興会

分泌型シアル酸認識レクチンによる関節再生メカニズムの解析
基盤研究(B)
徳島大学
2021年04月01日 - 2024年03月31日
山本 朗仁; 高橋 伸典; 加納 史也; 橋本 登, 山本 朗仁; 高橋 伸典; 加納 史也; 橋本 登, 日本学術振興会, Japan Society for the Promotion of Science

Ｗｎｔ/βカテニン・ＡＤＡＭ１０阻害による新規作用機序の変性関節症治療薬の開発
基盤研究(B)
名古屋大学
2019年04月01日 - 2022年03月31日
石黒 直樹; 高橋 伸典; 水野 正明; 平岩 秀樹; 大野 欽司; 大河原 美静, ISHIGURO Naoki, 日本学術振興会, Japan Society for the Promotion of Science

外因性hyaluronanの軟骨細胞における役割の解明
基盤研究(C)
名古屋大学
2020年04月01日 - 2021年03月31日
横田 裕; 寺部 健哉; 高橋 伸典, 横田 裕; 寺部 健哉; 高橋 伸典, 日本学術振興会, 日本学術振興会

Drug repositioning 戦略による整形外科領域の新規医療開発
基盤研究(B)
名古屋大学
2016年04月01日 - 2019年03月31日
石黒 直樹; 高橋 伸典; 鬼頭 浩史; 今釜 史郎; 水野 正明; 酒井 忠博, ISHIGURO NAOKI, 日本学術振興会, Japan Society for the Promotion of Science

ヒアルロン酸レセプターCD44の断片化阻害による、軟骨細胞の脱分化抑制効果
基盤研究(C)
2016年04月 - 2019年03月
日本学術振興会, 日本学術振興会

Dkk1分子発現亢進による新規変形性関節症治療薬の開発
挑戦的萌芽研究
名古屋大学
2016年04月01日 - 2018年03月31日
石黒 直樹; 酒井 忠博; 平岩 秀樹; 高橋 伸典, Ishiguro Naoki, 日本学術振興会, Japan Society for the Promotion of Science

関節リウマチに対する抗RANKL抗体と炎症性サイトカイン阻害薬併用療法の治療効果
基盤研究(C)
名古屋大学
2014年04月01日 - 2017年03月31日
小嶋 俊久; 小嶋 雅代; 吉岡 裕; 舟橋 康治; 平原 慎也; 平野 裕司; 林 真利; 矢部 裕一朗; 小口 武; 藤林 孝義; 高木 英希; 金山 康秀; 石黒 直樹; 高橋 伸典; 舟橋 康治; 浅井 秀司, Kojima Toshihisa; KOJIMA Masayo; YOSHIOKA Yutaka; FUNAHASHI Koji; HIRABARA shinya; HIRANO Yuji; HAYASHI Masatoshi; YABE Yuichiro; OGUCHI Takeshi; FUJIBAYASHI Takayoshi; TAKAGI Hideki; KANAYAMA Yasuhide, 日本学術振興会, Japan Society for the Promotion of Science

ヒアルロン酸レセプターCD44の断片化阻害による、軟骨細胞の脱分化抑制効果
基盤研究(C)
2013年04月 - 2016年03月
日本学術振興会, 日本学術振興会

ヒアルロン酸レセプターCD44の断片化阻害による、軟骨細胞の脱分化抑制効果
若手研究(B)
2011年04月 - 2013年03月
日本学術振興会, 日本学術振興会