masubuchi satoru
Physiology | Professor |
Profile
Research area
生理学
時間生物学Main lectures
生理学
行動科学Graduating school
弘前大学医学部医学科（1995年）Final Education
北海道大学大学院医学研究科（2001年）Previous workplace
栃木県済生会宇都宮病院（1995年5月～1997年3月）
神戸大学（2001年4月～2007年9月）
北海道大学（2011年1月～2014年1月）Study abroad experience
UCIrvine（米国）薬理学部（2007年10月～2010年12月）Main academic activities
日本生理学会
日本時間生物学会
日本睡眠学会Main research topic
時間生物学
Research Keyword
Paper
- 17β-Estradiol and cathepsins control primordial follicle growth in mouse ovaries.
Kouji Komatsu; Wei Wei; Tomohiko Murase; Satoru Masubuchi
Reproduction (Cambridge, England), Sep. 2021
162(4), 277, 287, 10.1530/REP-20-0599 - Increased supply from blood vessels promotes the activation of dormant primordial follicles in mouse ovaries.
Kouji Komatsu; Satoru Masubuchi
The Journal of reproduction and development, Apr. 2020, Reviewed, No invitation
66(2), 105, 113, 10.1262/jrd.2019-091 - Mouse oocytes connect with granulosa cells by fusing with cell membranes and form a large complex during follicle development.
Komatsu K; Masubuchi S
Biology of reproduction, Sep. 2018, Reviewed, No invitation
99(3), 527, 535, 10.1093/biolre/ioy072 - Ovarian Tissue Culture to Visualize Phenomena in Mouse Ovary.
Kouji Komatsu; Akira Iwase; Tomohiko Murase; Satoru Masubuchi
Journal of visualized experiments : JoVE, Jun. 2018, Reviewed, No invitation
(136), 10.3791/57794 - The concentration-dependent effect of progesterone on follicle growth in the mouse ovary
Kouji Komatsu; Satoru Masubuchi
JOURNAL OF REPRODUCTION AND DEVELOPMENT, Jun. 2017, Reviewed, No invitation
63(3), 271, 277, 10.1262/jrd.2016-154 - Observation of the dynamics of follicular development in the ovary
Kouji Komatsu; Satoru Masubuchi
Reproductive Medicine and Biology, Jan. 2017, Reviewed, No invitation
16(1), 21, 27, 10.1002/rmb2.12010 - Differential regulation of circadian melatonin rhythm and sleep-wake cycle by bright lights and nonphotic time cues in humans
Yujiro Yamanaka; Satoko Hashimoto; Satoru Masubuchi; Akiyo Natsubori; Shin-ya Nishide; Sato Honma; Ken-ichi Honma
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, Sep. 2014, Reviewed, No invitation
307(5), R546, R557, 10.1152/ajpregu.00087.2014 - Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1
Saurabh Sahar; Satoru Masubuchi; Kristin Eckel-Mahan; Simone Vollmer; Luisa Galla; Nicholas Ceglia; Selma Masri; Teresa K. Barth; Benedetto Grimaldi; Opeyemi Oluyemi; Giuseppe Astarita; William C. Hallows; Daniele Piomelli; Axel Imhof; Pierre Baldi; John M. Denu; Paolo Sassone-Corsi
JOURNAL OF BIOLOGICAL CHEMISTRY, Feb. 2014, Reviewed, No invitation
289(9), 6091, 6097, 10.1074/jbc.M113.537191 - Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition
Mark S. Sharpley; Christine Marciniak; Kristin Eckel-Mahan; Meagan McManus; Marco Crimi; Katrina Waymire; Chun Shi Lin; Satoru Masubuchi; Nicole Friend; Maya Koike; Dimitra Chalkia; Grant MacGregor; Paolo Sassone-Corsi; Douglas C. Wallace
CELL, Oct. 2012, Reviewed, No invitation
151(2), 333, 343, 10.1016/j.cell.2012.09.004 - Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock
Satoru Masubuchi; Tianyan Gao; Audrey O'Neill; Kristin Eckel-Mahan; Alexandra C. Newton; Paolo Sassone-Corsi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Jan. 2010, Reviewed, No invitation
107(4), 1642, 1647, 10.1073/pnas.0910292107 - Circadian Biology: An Unexpected Invitee to New Time Zones
Satoru Masubuchi; Paolo Sassone-Corsi
CURRENT BIOLOGY, Apr. 2009, Reviewed, No invitation
19(7), R298, R300, 10.1016/j.cub.2009.02.016 - Chromatin remodeling, metabolism and circadian clocks: The interplay of CLOCK and SIRT1
Benedetto Grimaldi; Yasukazu Nakahata; Milota Kaluzova; Satoru Masubuchi; Paolo Sassone-Corsi
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, Jan. 2009, Reviewed, No invitation
41(1), 81, 86, 10.1016/j.biocel.2008.08.035 - FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets
Naonobu Nishino; Yoshikazu Tamori; Sanshiro Tateya; Takayuki Kawaguchi; Tetsuro Shibakusa; Wataru Mizunoya; Kazuo Inoue; Riko Kitazawa; Sohei Kitazawa; Yasushi Matsuki; Ryuji Hiramatsu; Satoru Masubuchi; Asako Omachi; Kazuhiro Kimura; Masayuki Saito; Taku Amo; Shigeo Ohta; Tomohiro Yamaguchi; Takashi Osumi; Jinglei Cheng; Toyoshi Fujimoto; Harumi Nakao; Kazuki Nakao; Atsu Aiba; Hitoshi Okamura; Tohru Fushiki; Masato Kasuga
JOURNAL OF CLINICAL INVESTIGATION, Aug. 2008, Reviewed, No invitation
118(8), 2808, 2821, 10.1172/JCI34090 - Establishment of 14 wheat lines carrying telosomes of barley chromosome 7H
Nishino N; Tamori Y; Tateya S; Kawaguchi T; Shibakusa T; Mizunoya W; Inoue K; Kitazawa R; Kitazawa S; Matsuki Y; Hiramatsu R; Masubuchi S; Omachi A; Kimura K; Saito M; Amo T; Ohta S; Yamaguchi T; Osumi T; Cheng J; Fujimoto T; Nakao H; Nakao K; Aiba A; Okamura H; Fushiki T; Kasuga M
J Clin Invest. 2008 Aug;118(8):2808-21., 2008, Reviewed, No invitation - Vagal regulation of respiratory clocks in mice
Hideki Bando; Takeshi Nishio; Gijsbertus T. J. van der Horst; Satoru Masubuchi; Yasuo Hisa; Hitoshi Okamura
JOURNAL OF NEUROSCIENCE, Apr. 2007, Reviewed, No invitation
27(16), 4359, 4365, 10.1523/JNEUROSCI.4131-06.2007 - Light activates the adrenal gland: Timing of gene expression and glucocorticoid release
A Ishida; T Mutoh; T Ueyama; H Bando; S Masubuchi; D Nakahara; G Tsujimoto; H Okamura
CELL METABOLISM, Nov. 2005, Reviewed, No invitation
2(5), 297, 307, 10.1016/j.cmet.2005.09.009 - Mouse period1 (mPER1) acts as a circadian adaptor to entrain the oscillator to environmental light/dark cycles by regulating mPER2 protein
S Masubuchi; N Kataoka; P Sassone-Corsi; H Okamura
JOURNAL OF NEUROSCIENCE, May 2005, Reviewed, No invitation
25(19), 4719, 4724, 10.1523/JNEUROSCI.4761-04.2005 - Gene expression of neuropeptide Y in the nucleus of the solitary tract is activated in rats under restricted daily feeding but not under 48-h food deprivation
K Ishizaki; S Honma; Y Katsuno; H Abe; S Masubuchi; M Namihira; K Honma
EUROPEAN JOURNAL OF NEUROSCIENCE, May 2003, Reviewed, No invitation
17(10), 2097, 2105, 10.1046/j.1460-9568.2003.02672.x - ラット新生仔の時計遺伝子発現リズムに対する母ラット保育行動の影響
太田 英伸; 本間 さと; 安倍 博; 波平 昌一; 増渕 悟; 本間 研一
日本生理学雑誌, Jan. 2002
64(1), 21, 22 - Circadian activity rhythm in methamphetamine-treated Clock mutant mice.
Masubuchi S; Honma S; Abe H; Nakamura W; Honma K
The European journal of neuroscience, Oct. 2001, Reviewed, No invitation
14(7), 1177, 1180, 10.1046/j.0953-816X.2001.01749.x - CS系マウスの摂食サイクルへの行動リズム同調と脳のmPer遺伝子発現リズム
安倍 博; 本間 さと; 波平 昌一; 増渕 悟; 太田 英伸; 本間 研一
神経化学, Sep. 2001
40(2-3), 292, 292 - Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise
T Miyazaki; S Hashimoto; S Masubuchi; S Honma; KI Honma
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, Jul. 2001, Reviewed, No invitation
281(1), R197, R205 - Circadian pattern, light responsiveness and localization of rPer1 and rPer2 gene expression in the rat retina
M Namihira; S Honma; H Abe; S Masubuchi; M Ikeda; K Honma
NEUROREPORT, Mar. 2001, Reviewed, No invitation
12(3), 471, 475 - Clock gene expressions in the suprachiasmatic nucleus and other areas of the brain during rhythm splitting in CS mice
H Abe; S Honma; M Namihira; S Masubuchi; M Ikeda; S Ebihara; K Honma
MOLECULAR BRAIN RESEARCH, Feb. 2001, Reviewed, No invitation
87(1), 92, 99, 10.1016/S0169-328X(00)00295-3 - Clock genes outside the suprachiasmatic nucleus involved in manifestation of locomotor activity rhythm in rats
S Masubuchi; S Honma; H Abe; K Ishizaki; M Namihira; M Ikeda; K Honma
EUROPEAN JOURNAL OF NEUROSCIENCE, Dec. 2000, Reviewed, No invitation
12(12), 4206, 4214, 10.1046/j.1460-9568.2000.01313.x - Amplitude reduction of plasma melatonin rhythm in association with an internal desynchronization in a subject with non-24-hour sleep-wake syndrome
S Masubuchi; S Hashimoto; T Endo; S Honma; K Honma
PSYCHIATRY AND CLINICAL NEUROSCIENCES, Apr. 1999, Reviewed, No invitation
53(2), 249, 251, 10.1046/j.1440-1819.1999.00535.x
MISC
- 低酸素によるマウス活動期活動量の変化は時計遺伝子によらない波様の反応が決定している
増渕悟; 矢野多佳子; 小松紘司; 中村渉; 太田明伸; シバスンダラン カルナン; 武内恒成; 細川好孝; 藤堂剛; 塩見利明
日本生理学雑誌(Web), Feb. 2019, Not reviewed, No invitation
81(1), WEB ONLY - 運動と睡眠 再検討 光と運動によるヒト生物時計の調節メカニズム
山仲 勇二郎; 橋本 聡子; 高須 奈々; 増渕 悟; 夏堀 晃世; 棚橋 祐典; 西出 真也; 本間 さと; 本間 研一
日本睡眠学会定期学術集会プログラム・抄録集, Jul. 2015, Not reviewed, No invitation
40回, 136, 136 - 高照度光下での運動が生体リズムおよび睡眠に与える影響
山仲 勇二郎; 橋本 聡子; 増渕 悟; 夏堀 晃世; 西出 真也; 本間 さと; 本間 研一
体力科学, Jun. 2015, Not reviewed, No invitation
64(3), 385, 385 - 高照度光下での身体運動は8時間位相前進シフトした生活スケジュールへの血中メラトニンリズムの再同調を促進する
山仲 勇二郎; 橋本 聡子; 増渕 悟; 夏堀 晃世; 西出 真也; 本間 さと; 本間 研一
日本睡眠学会定期学術集会プログラム・抄録集, Jun. 2013, Not reviewed, No invitation
38回, 179, 179 - Somatostatinergic clock gatekeeping in the suprachiasmatic nucleus controls entrainment to photoperiod
Satoru Masubuchi; Takayuki Yamasaki; Kazuto Kobayashi; Hitoshi Okamura
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not reviewed, No invitation
63, S145, S145 - Effects of timed physical exercise on phase shifts of human circadian rhythms induced by 8-h advance shift of sleep schedule under bright light conditions
Yujiro Yamanaka; Satoko Hashimoto; Satoru Masubuchi; Akiyo Natsubori; Shin-ya Nishide; Sato Honma; Ken-ichi Honma
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2013, Not reviewed, No invitation
63, S259, S259 - [Crosstalk between central and peripheral biological clocks].
Masubuchi S; Suzuki Y; Honma S
Nihon rinsho. Japanese journal of clinical medicine, Jul. 2012, Reviewed, No invitation
70, 1127, 1132 - Sleep research by analysis of model animal: characteristics of human sleep and establishment of the animal model for human sleep-wake rhythm disorder
増渕 悟; 本間 さと; 本間 研一
Cell technology., May 2008
27(5), 456, 460 - Methamphetamine induces circadian oscillation in the brain outside the suprachiasmatic nucleus in rats
S.Masubuchi; S.Honma; H.Abe; M.Namihira; K.Honma
Sleep and Biological Rhythms, 2007, Not reviewed, No invitation
5, 132, 140, 10.1111/j.1479-8425.2007.00263.x - Molecular Network of Biological Clock
OKAMURA Hitoshi; MASUBUCHI Satoru; UEYAMA Tomoko
ホルモンと臨牀, 01 Jun. 2005, Not reviewed, No invitation
53(6), 603, 610 - 時計遺伝子のフィードバックループ (特集 生体時計と概日リズム)
岡村 均; 増渕 悟; 市原 直征
神経研究の進歩, Oct. 2001, Not reviewed, No invitation
45(5), 755, 762 - Behavioral rhythm splitting in the CS mouse is related to clock gane expression outside the suprachiasmatic nucleus
H.Abe; S.Honma; M.Namihira; S.Masubuchi; K.Honma
European Journal of Neuroscience, 2001, Not reviewed, No invitation
14, 1121, 1128, 10.1046/j.0953-816X.2001.01732.x - マウス行動リズム異常と視交叉上核 Period 遺伝子発現リズム
安倍 博; 本間 さと; 波平 昌一; 増渕 悟; 本間 研一
日本時間生物学会会誌: Journal of Chronobiology, 01 Oct. 2000, Not reviewed, No invitation
6(2) - 日長変化によるヒト生体リズムへの影響
橋本 聡子; 本間 研一; 遠藤 拓郎; 増渕 悟; 本間 さと
日本生気象学会雑誌, 23 Oct. 1999, Not reviewed, No invitation
36(3) - 給餌性サｰカディアンリズムの発現における Arginine Vasopressin(AVP) と Corticotropin Releasing Hormone(CRH) の差異
勝野 由美子; 増渕 悟; 波平 昌一; 安倍 博; 本間 さと; 本間 研一
日本時間生物学会会誌: Journal of Chronobiology, 01 Oct. 1999, Not reviewed, No invitation
5(2), 72, 72 - 周期的制限給餌(RF)下に於けるラット脳内NPY動態
石崎 高司; 本間 さと; 安倍 博; 増渕 悟; 波平 昌一; 本間 研一
日本時間生物学会会誌: Journal of Chronobiology, 01 Oct. 1999, Not reviewed, No invitation
5(2) - 周期的制限給餌(RF)下のリズム発現に於ける脳内NPYの役割 : リアルタイムPCR(プリズム)を用いたNPYmRNAの定量的解析
石崎 高司; 本間 さと; 安倍 博; 波平 昌一; 増渕 悟; 本間 研一
日本生気象学会雑誌, 29 Jan. 1999, Not reviewed, No invitation
35(3) - 低照度環境下におけるヒト生体リズムの同調
橋本 聡子; 本間 研一; 増渕 悟; 宮崎 俊彦; 遠藤 拓郎; 本間 さと
日本生気象学会雑誌, 29 Jan. 1999, Not reviewed, No invitation
35(3) - Methamphetamine(MAP) 慢性投与ラットにおける松果体、血漿メラトニンリズムと行動リズムの乖離
増渕 悟; 本間 さと; 石崎 高司; 波平 昌一; 橋本 聡子; 本間 研一
日本生気象学会雑誌, 29 Jan. 1999, Not reviewed, No invitation
35(3) - 非光因子(強制的睡眠･覚醒スケジュｰル)によるヒトサｰカディアンリズムの同調
橋本 聡子; 本間 研一; 宮崎 俊彦; 増渕 悟; 遠藤 拓郎; 本間 さと
日本時間生物学会会誌: Journal of Chronobiology, 01 Oct. 1998, Not reviewed, No invitation
4(2) - ヒトフリｰラン周期の経時変化と照度依存性
遠藤 拓郎; 橋本 聡子; 増渕 悟; 本間 さと; 本間 研一
日本時間生物学会会誌: Journal of Chronobiology, 01 Oct. 1998, Not reviewed, No invitation
4(2)
Research Themes
- 不眠を伴う睡眠時無呼吸症候群(COMISA)のモデル動物作成と解析による病態解明
基盤研究(C)
愛知医科大学
01 Apr. 2022 - 31 Mar. 2025
増渕 悟, 増渕 悟, 日本学術振興会, 日本学術振興会 - Analysis of molecular mechanism in circadian intraocular pressure rhythm
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
01 Apr. 2019 - 31 Mar. 2022
池上 啓介; 増渕 悟, Ikegami Keisuke, 日本学術振興会, Japan Society for the Promotion of Science - Identification of interrelationships between hypoxia in tumor and biological clock for chronotherapy
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
01 Apr. 2016 - 31 Mar. 2020
増渕 悟, Masubuchi Satoru, 日本学術振興会, Japan Society for the Promotion of Science - 時間治療のための腫瘍内低酸素と生物時計の相互作用の解明
2016 - 2018
増渕悟, 増渕悟, 文部科学省, 文部科学省, Principal investigator - Analysis of cancer cell clock for chronotherapy
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
01 Apr. 2013 - 31 Mar. 2016
増渕 悟, Masubuchi Satoru, 日本学術振興会, Japan Society for the Promotion of Science - 時間治療を目指した腫瘍細胞概日時計の多様性の解明
2013 - 2015
増渕悟, 増渕悟, 文部科学省, 文部科学省, Principal investigator - Analysis of clock oscillation in cancer tissue for effective chronotherapy to hypoxic area.
Grant-in-Aid for Research Activity start-up
Hokkaido University
2011 - 2012
増渕 悟, MASUBUCHI Satoru, 日本学術振興会, Japan Society for the Promotion of Science, Principal investigator - Molecular Clocks to Biological Rhythms
Grant-in-Aid for Specially Promoted Research
神戸大学->京都大学
2006 - 2010
岡村 均; 江本 憲昭; 増渕 悟; 土居 雅夫; 飯郷 雅之; 中原 大一郎; 中尾 和貴; 山口 賀章; 松尾 雅博, OKAMURA Hitoshi; EMOTO Noriaki; MASUBUCHI Satoru; DOI Masao; IIGO Masayuki; NAKAHARA Daiichiro; NAKAO Kazuki; YAMAGUCHI Yoshiaki; MATSUO Masahiro, 日本学術振興会, Japan Society for the Promotion of Science, Coinvestigator not use grants - 遺伝子改変動物を用いた生物時計中枢を構成するコンパートメントの機能解明
若手研究(B)
神戸大学
2006 - 2007
増渕 悟, 増渕 悟, 日本学術振興会, 日本学術振興会, Principal investigator - 細胞から個体までのリズム遺伝子発現の統合システムの解析
基盤研究(A)
神戸大学
2005 - 2006
岡村 均; 増渕 悟; 江本 憲昭; 土居 雅夫; 上山 友子, 岡村 均; 増渕 悟; 江本 憲昭; 土居 雅夫; 上山 友子, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants - 細胞時計による生死決定とがん化の研究
特定領域研究
神戸大学
2005 - 2005
岡村 均; 増渕 悟, 岡村 均; 増渕 悟, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants - 脳における時間シグナルの構築
特定領域研究
神戸大学
2005 - 2005
岡村 均; 増渕 悟, 岡村 均; 増渕 悟, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants - Clarification of molecular mechanism of Jet Lag
Grant-in-Aid for Scientific Research (C)
Kobe University
2004 - 2005
増渕 悟; 岡村 均, MASUBUCHI Satoru; OKAMURA Hitoshi, 日本学術振興会, Japan Society for the Promotion of Science, Principal investigator - 発がん時の細胞時計の研究
特定領域研究
神戸大学
2004 - 2004
岡村 均; 増渕 悟, 岡村 均; 増渕 悟, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants
