YOKOYAMA Yukihiro

Department of Surgical Perioperative ManagementProfessor

Research Keyword

  • 肝臓の病態生理学
  • Surgical Oncology/Hepatobiliary Pancreatic Surgery and Liver Physiology

Paper

MISC

Books and other publications

  • 患者さんのための膵がん診療ガイドラインの解説
    横山幸浩, Single work
    金原出版, May 2015, Not reviewed
    35-36
  • Cholangiocarcinoma
    Mizuno T; Ebata T; Yokoyama Y; Sugawara G; Nagino M, Joint work
    Nova Science Publishers, 2015, Not reviewed
    20, 299-318
  • 核酸医薬開発の現状と展望
    國料俊男; 横山幸浩; 梛野正人, Joint work
    飯田橋パピルス, 2015, Not reviewed
    101-108
  • 常在細菌叢が操るヒトの健康と疾患 高度外科侵襲手術における周術期シンバイティクス投与の有用性
    横山幸浩; 梛野正人, Joint work
    羊土社, 2014, Not reviewed
    124-129
  • The Current Scenario: Advanced Resectable Gallbladder Cancer, Diagnosis and Surgical Approach.
    Igami T; Ebata T; Yokoyama Y; Sugawara G; Nagino M, Joint work
    Elsevier Clinical Advisory Board, 2013, Not reviewed
    0000
  • 胆道がん 管理・治療・予後
    伊神剛; 江畑智希; 横山幸浩; 菅原元; 梛野正人, Joint work
    最新医学, 2011, Not reviewed
    184-194
  • Venous Embolization of the Liver: Radiological and Surgical Practice. Sequential PVE and TAE for biliary tract cancer and liver metastases.
    Yokoyama Y; Nagino M, Joint work
    Springer, Jul. 2010, Not reviewed
    241-248
  • Venous Embolization of the Liver: Radiological and Surgical Practice. Biliary tract cancer.
    Yokoyama Y; Nagino M, Joint work
    Springer, Jul. 2010, Not reviewed
    191-200
  • An overview of pancreatic cancer
    Yukihiro Yokoyama, Single work
    特定非営利活動法人 パンキャンジャパン, Jan. 2010, Not reviewed
    16
  • Female Hepatology; Impact of female sex against progression of liver disease: Gender dimorphic response to hepatic vascular stress
    Yukihiro Yokoyama; Irshad H. Chaudry, Joint work
    RESEARCH SIGNPOST, 2009, Not reviewed
    227-244
  • 胆道外科の要点と盲点 第2版
    横山幸浩, Joint work
    文光堂, Jan. 2009, Not reviewed
    32-33, 37-41, 214-215, 220-221, 248-249412-414
  • Cancer Imaging Vol2. Chronic pancreatitis versus pancreatic cancer: positron emission tomography
    Yukihiro Yokoyama; Masato Nagino; Yuji Nimura, Joint work
    Elsevier, Jan. 2008, Not reviewed
    541-546
  • 肝再生の開始機構は何か？
    横山幸浩; 小林聡; 笹本彰紀; 河合正巳; 梛野正人, Joint work
    先端医学社, Dec. 2007, Not reviewed
    298-307
  • Endothelium Biomedicine. Trauma-hemorrhage and its effects on the endothelium with particular emphasis on gender dimorphism.
    Yukihiro Yokoyama; Irshad H. Chaudry, Joint work
    Cambridge University Press, Jul. 2007, Not reviewed
    1513-1522
  • がんの新辞典 からだの科学: 膵がん
    横山幸浩; 梛野正人; 二村雄次, Joint work
    日本評論社, 2007, Not reviewed
    62-66
  • 消化器外科学レビュー: 最新文献と解説: 胆嚢炎、胆管炎
    横山幸浩; 梛野正人; 二村雄次, Joint work
    総合医学社, 2007, Not reviewed
    121-126

Lectures, oral presentations, etc.

  • Surgeon initiated basic science research for the mechanisms of biliary obstruction-induced liver injury.
    Yokoyama Y
    24th World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists., 05 Dec. 2014, No invitation
    Oral presentation, Domestic conference
  • The adverse effect of preoperative cholangitis on the outcome of portal vein embolization and subsequent major hepatectomy.
    Yokoyama Y; Ebata T; Igami T; Sugawara G; Mizuno T; Nagion M
    11th World Congress of International Hepato-Pancreato-Biliary Association., 22 Mar. 2014, No invitation
    Oral presentation, Domestic conference
  • A predictive power of prothrombin time and serum total bilirubin for postoperative mortality after major hepatectomy with extrahepatic bile duct resection.
    Yokoyama Y; Ebata T; Igami T; Sugawara G; Mizuno T; Nagino M
    11th World Congress of International Hepato-Pancreato-Biliary Association., 22 Mar. 2014, No invitation
    Oral presentation, Domestic conference
  • Surgical basic sciences for the treatment against hepato-biliary-pancreatic cancer. A research work conducted by active surgeons.
    Yokoyama Y
    Seoul International Symposium of Surgical Oncology 2014, 07 Mar. 2014, No invitation
    Oral presentation, Domestic conference
  • Perioperative synbiotics treatment reduces postoperative bacteremia through suppression of bacterial translocation following highly invasive surgeries.
    Yokoyama Y
    Seoul International Symposium of Surgical Oncology 2014, 07 Mar. 2014, No invitation
    Oral presentation, Domestic conference
  • Perioperative synbiotics treatment reduces postoperative bacteremia through suppression of bacterial translocation following highly invasive surgeries.
    Yokoyama Y
    8th Asia Pacific Conference on Clinicla Nutrition (APCCN2013)., 10 Jun. 2013, No invitation
    Oral presentation, Domestic conference
  • Gene profile related to the inhibitory effects of alpha-Bisabolol on cellular invasion of pancreas cancer.
    Yokoyama Y; Uno M; Kokuryo T; Nagino M
    9th AACR-Japanese Cancer Association Joint Conference., 21 Feb. 2013, No invitation
    Poster presentation, Domestic conference
  • The incidence of intraoperative bacterial translocation and its clinical impact on the postoperative course in highly invasive surgeries.
    Yokoyama Y; Mizuno T; Abe T; Nishigaki E; Fukaya M; Asahara T; Nomoto K; Nagino M
    22nd World Congress of the International Association of Surgeons, Gastroenterologists, and Oncologists (IASGO)., 04 Dec. 2012, No invitation
    Oral presentation, Domestic conference
  • Risk factors of incisional surgical site infection (I-SSI) in the elective hepato-pancreato-biliary surgery: A multi-institutional prospective study.
    Yokoyama Y; Itatsu K; Kaneoka Y; Kato T; Kanai M; Sugawara G; Nagino M
    Congress of the International Association of Surgeons, Gastroenterologists, and Oncologists (IASGO)., 04 Dec. 2012, No invitation
    Oral presentation, Domestic conference
  • Intraoperative bacterial translocation detected by bacterium-specific ribosomal RNA-targeted RTqPCR for the mesenteric lymph node strongly predicts postoperative infectious complications.
    Yokoyama Y; Mizuno T; Sugawara G; Asahara T; Nomoto K; Nagino M
    The 25th European Congress on Surgical Infection., 14 Jun. 2012, No invitation
    Oral presentation, Domestic conference
  • Beneficial effects of inchinkoto, a herbal medicine, against the stress of major liver surgery.
    Yokoyama Y; Kawai K; Kokuryo T; Watanabe K; Kitagawa T; Nagino M
    The 3rd Biennial Asian Pacific HPBA Congress., 27 Sep. 2011, No invitation
    Oral presentation, Domestic conference
  • The effects of segmental cholangitis on hepatic regeneration capacity following partial hepatectomy.
    Yokoyama Y; Watanabe K; Kokuryo T; Kawai K; Kitagawa T; Nagino M
    The 3rd Biennial Asian Pacific HPBA Congress, 27 Sep. 2011, No invitation
    Oral presentation, Australia, Domestic conference
  • Short-term outcomes of aggressive surgery for locally recurrent rectal cancer.
    Uehara K; Ishiguro S; Nishio H; Ebata T; Yokoyama Y; Igami T; Sugawara G; Fukaya M; Itatsu K; Nagino M
    The 15th European Society of Surgical Oncology., 15 Sep. 2010, No invitation
    Poster presentation, Domestic conference
  • Investigation of gastroesophageal reflex diseases after distal gastrectomy with esophagogastric junction morphology, manometry, combined pH and bilirubin monitoring.
    Fukaya M; Itatsu K; Uemura N; Miyata K; Ebata T; Yokoyama Y; Igami T; Sugawara G; Uehara K; Ishiguro S; Nagino M
    The 12th World Congress of International Society for Diseases of the Esophagus., 02 Sep. 2010, No invitation
    Poster presentation, Domestic conference
  • Hepatopancreatoduodenectomy for advanced gallbladder cancer: a Nagoya experience in the 2000s.
    Ebata T; Nishio H; Yokoyama Y; Igami T; Sugawara G; Nimura Y; Nagino M
    9th World Congress of the International Hepato-Pancreato-Biliary Association., 18 Apr. 2010, No invitation
    Nominated symposium, Domestic conference
  • Margin length of the right posterior sectorial duct in left-sided hepatectomy for perihilar cholangiocarcinoma.
    Natsume S; Ebata T; Sugawara G; Nishio H; Kokuryo T; Yokoyama Y; Tsunoda N; Fukaya M; Uehara K; Nagino M
    9th World Congress of the International Hepato-Pancreato-Biliary Association., 18 Apr. 2010, No invitation
    Poster presentation, Domestic conference
  • Combined hepatic artery resction for perihilar cholangiocarcinoma: histologic analysis in 59 patients.
    Fukami Y; Ebata T; Nishio H; Yokoyama Y; Kokuryo T; Tsunoda N; Igami T; Sugawara G; Fukaya M; Uehara K; Shimoyama Y; Nagino M
    9th World Congress of the International Hepato-Pancreato-Biliary Association, 18 Apr. 2010, No invitation
    Poster presentation, Domestic conference
  • Management of patients with MRSA-bactbilia for hepatobiliary resection.
    Takara D; Ebata T; Sugawara G; Nishio H; Kokuryo T; Yokoyama Y; Tsunoda N; Igami T; Fukaya M; Uehara K; Nagino M
    9th World Congress of the International Hepato-Pancreato-Biliary Association, 18 Apr. 2010, No invitation
    Poster presentation, Domestic conference
  • Nek2 as an effective molecular target for cancer treatment.
    Kokuryo T; Senga T; Yokoyama Y; Nagino M; Hagaguchi M
    The 101th American Association for Cancer Research., 17 Apr. 2010, No invitation
    Poster presentation, Washington DC., Domestic conference
  • Cytoplasmic expression of Glc-GlcNh3+ on heparin sulfate closely correlates with malignancy of breast cancer.
    Fujii M; Yuasa A; Yokoyama Y; Kokuryo T; Nagino M; Iwata H; Utsunomiya H; Ishimaru T; Kyogashima M; Knnagi R
    The 20th International Symposium on Glycoconjuate., 29 Nov. 2009, No invitation
    Poster presentation, Domestic conference
  • Nek2 as a novel molecular target for inhibition of tumorigenic growth and liver metastasis of pancreatic cancer.
    Suzuki K; Kokuryo T; Senga T; Yokoyama Y; Nagino M; Hamaguchi M
    GASTRO 2009 UEGW/WCOG, 21 Nov. 2009, No invitation
    Poster presentation, Domestic conference
  • The mechanism of protective effect of PPAR gamma; activation on bile duct ligation-induced hepatic injury in rats.
    Kitagawa T; Yokoyama Y; Kokuryo T; Kawai K; Watanabe K; Nagino M
    60th Annual Meeting of The American Association for the Study of Liver Diseases, 30 Oct. 2009, No invitation
    Poster presentation, Domestic conference
  • 15-Deoxy-Δ12,14-Prostaglandin J2 prevents inflammatory response and endothelial cell damage in rats with acute obstructive cholangitis.
    Yokoyama Y; Watanabe K; Kokuryo T; Kawai K; Kitagawa T; Seki T; Nakagawa A; Nagino M
    60th Annual Meeting of The American Association for the Study of Liver Diseases, 30 Oct. 2009, No invitation
    Poster presentation, Domestic conference
  • The value of ICG clearance rate of the future liver remnant in predicting postoperative morbidity following major hepatectomy for biliary cancer.
    Yokoyama Y; Nishio H; Ebata T; Igami T; Sugawara G; Uehara K; Nagino M
    4th Annual Academic Surgical Congress, 06 Mar. 2009, No invitation
    Oral presentation, Domestic conference
  • Five-year survivors after surgery for gallbladder cancer involving the extrahepatic bile duct.
    Nishio H; Ebata T; Igami T; Yokoyama Y; Uehara K; Abe T; Oda K; Nagino M
    8th World Congress of the International Hepato Pancreato Biliary Association., 27 Feb. 2008, International Hepato Pancreato Biliary Association, No invitation
    Oral presentation, Domestic conference
  • Additional resection of margin-positive proximal bile duct does not improve survival in patients with hilar cholangiocarcinoma.
    Shingu Y; Oda K; Nishio H; Ebata T; Yokoyama Y; Abe T; Igami T; Nagino M
    8th World Congress of the International Hepato Pancreato Biliary Association., 27 Feb. 2008, The International Hepato Pancreato Biliary Association, No invitation
    Oral presentation, Domestic conference
  • Proposal of new classification for cystic duct carcinoma.
    Yokoyama Y; Nishio H; Ebata T; Yokoyama Y; Abe T; Igami T; Oda K; Nimura Y; Nagino M
    8th World Congress of the International Hepato Pancreato Biliary Association, 27 Feb. 2008, The International Hepato Pancreato Biliary Association, No invitation
    Oral presentation, Domestic conference
  • Pancreatic and duodenal invasion in distal bile duct cancer: paradox in the tumor classification of the American Joint Committiee on Cancer.
    Ebata T; Nishio H; Igami T; Yokoyama Y; Nimura Y; Nagino M
    8th World Congress of the International Hepato Pancreato Biliary Association, 27 Feb. 2008, The International Hepato Pancreato Biliary Association, No invitation
    Poster presentation, Domestic conference
  • The role of PPAR gamma; in bile duct ligation-induced hepatic injury in rats.
    Kitagawa T; Yokoyama Y; Kawai T; Watanabe K; Nagino M
    American Association for the Study of Liver Diseases, 02 Nov. 2007, American Association for the Study of Liver Diseases, No invitation
    Poster presentation, Domestic conference
  • Major hepatectomy with resection of the hilar bile duct and/or portal bifurcation for liver metastasis from colorectal cancer.
    Uehara K; Nagino M; Oda K; Nishio H; Ebata T; Yokoyama Y; Abe T; Igami T; Nimura Y
    The 11th Congress of Asian Federation of Coloproctology., 20 Sep. 2007, No invitation
    Poster presentation, Domestic conference
  • Does estrogen contribute to hepatic regeneration following portal branch ligation in rats?
    Yokoyama Y; Kawai T; Nagino M; Oda K; Nimura Y
    1st Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association, Mar. 2007, Asian-Pacific Hepato-Pancreato-Biliary Association, No invitation
    Poster presentation, Domestic conference
  • The new clinicopathological classification of mucin-producing bile duct tumors.
    Igami T; Nagino M; Oda K; Nishio H; Ebata T; Yokoyama Y; Abe T; Nimura Y
    1st Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association, Mar. 2007, Asian-Pacific Hepato-Pancreato-Biliary Association, No invitation
    Poster presentation, Domestic conference
  • Portal vein obstruction after hepatobiliary resection: countermeasure and treatment.
    Igami T; Nagino M; Oda K; Nishio H; Ebata T; Yokoyama Y; Abe T; Nimura Y
    1st Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association, Mar. 2007, Asian-Pacific Hepato-Pancreato-Biliary Association, No invitation
    Poster presentation, Domestic conference
  • Clinicopathologic features of recurrent intraductal papillary neoplasms (IPMNs).
    Yokoyama Y; Nagino M; Oda K; Nishio H; Ebata T; Abe T; Igami T; Nimura Y
    1st Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association, Mar. 2007, Asian-Pacific Hepato-Pancreato-Biliary Association, No invitation
    Poster presentation, Domestic conference
  • Clinicopathologic feature of recurrent cases of intraductal papillary mucinous neoplasms. Analysis of one hundred consecutive surgical cases in a single institution.
    Yokoyama Y; Nagino M; Oda K; Nishio H; Ebata T; Igami T; Nimura Y
    2nd Academic Surgical Congress, Feb. 2007, Society of University Surgeons, No invitation
    Oral presentation, Domestic conference
  • Is there any effect of renal failure on the hepatic regeneration capacity following partial hepatectomy in rats.
    Kawai T; Yokoyama Y; Nagino M; Nimura Y
    2nd Academic Surgical Congress, Feb. 2007, No invitation
    Poster presentation, Domestic conference
  • Hepatic trisectionectomy for hilar cholangiocarcinoma: Is it worthwhile?
    Nishio H; Nagino M; Ebata T; Igami T; Yokoyama Y; Nimura Y
    The 7th World Congress of the International Hepato-Pancreato Biliary Association, Sep. 2006, No invitation
    Oral presentation, Domestic conference
  • Mechanism of salutary effects of estradiol following trauma-hemorrhage.
    Yokoyama Y; Toth B; Kuebler JF; Ba ZF; Chaudry IH
    3rd World Shock Forum, 2006, No invitation
    Invited oral presentation, Domestic conference
  • The mechanism of oxygen radical-mediated bile flow reduction: the role of intracellular cyclic AMP.
    Kawai S; Arai T; Yokoyama Y; Nimura Y
    FASEB, 2005, No invitation
    Poster presentation, Domestic conference
  • Pancreatic abscess in chronic pancreatitis with positron accumulation by FDG-PET-A case report.
    Yokoyama Y; Hiromatsu T; Ebata T; Arai T; Oda K; Yuasa N; Nagino M; Nimura Y
    The 11th Meeting of the International Association of Pancreatology, 2004, No invitation
    Poster presentation, Domestic conference
  • Gender dimorphism in the outcome of preoperative portal embolization for major hepatectomy.
    Yokoyama Y; Nagino M; Yuasa N; Oda K; Arai T; Nishio H; Ebata T; Nimura Y
    19th-World Congress of International Society for Digestive Surgery, 2004, No invitation
    Oral presentation, Domestic conference
  • Immunopathogenesis following trauma-hemorrhagic shock and possibilities of immune modulation.
    Chaudry IH; Matsutani T; Yokoyama Y; Matsushima A; Suzuki T; Shimizu T; Choudhry M; Rue L; Schwacha M; Bland KI
    1st World Shock Forum, 25 Oct. 2003, No invitation
    Invited oral presentation, International conference
  • IL-6 plays a ;major role in producing hepatic injury following trauma-hemorrhage.
    Toth B; Yokoyama Y; Schwacha M; Bland KI; Chaudry IH
    Shock, 07 Jun. 2003, No invitation
    Oral presentation, Domestic conference
  • Portal venous response to endothelin-1 is attenuated by 17-estradiol treatment following trauma-hemorrhage.
    Yokoyama Y; Toth B; Kitchens WC; Schwacha MG; Bland KI; Chaudry IH
    Shock, 07 Jun. 2003, No invitation
    Poster presentation, Domestic conference
  • Gender differences in small intestinal endothelial function: androgen plays an inhibitory role.
    Ba ZF; Yokoyama Y; Bland KI; Chaudry IH
    Shock, 07 Jun. 2003, No invitation
    Poster presentation, Domestic conference
  • Mechanism of the salutary effect of 17beta-estradiol following trauma-hemorrhage: Direct downregulation of Kupffer cell IL-6 gene expression and release.
    Yokoyama Y; Kuebler JF; Matsutani T; Bland KI; Wang P; Chaudry IH
    Shock, 08 Jun. 2002, No invitation
    Oral presentation, Domestic conference
  • Gender dimorphism in hepatic heme oxygenase expression and activity after trauma and hemorrhagic shock.
    Toth B; Yokoyama Y; Kuebler JF; Schawacha MG; Wang P; Bland KI; Chaudry IH
    Shock, 08 Jun. 2002, No invitation
    Oral presentation, Domestic conference
  • Kuffper cells are the major source of thromboxane A2 (TXA2) in bile duct ligation induced cirrhosis.
    Xu H; Yokoyama Y; Sarmadi AH; Clemens MG; Zhang JX
    FASEB, 20 Apr. 2002, No invitation
    Oral presentation, Domestic conference
  • Role of thromboxane A2 (TXA2) in portal hypertension in bile duct ligated rat liver.
    Yokoyama Y; Xu H; Sarmadi AH; Baveja R; Clemens MG; Zhang JX
    America Association for the Study of Liver Diseases, 09 Nov. 2001, No invitation
    Poster presentation, Domestic conference
  • Overexpression of Caveolin-1: a potential mechanism for a hyperresponse of hepatic microcirculation to endothelins during sepsis.
    Ashburn J; Baveja R; Yokoyama Y; Huynh T; Clemens MG
    Shock, 09 Jun. 2001, No invitation
    Poster presentation, International conference
  • Altered in vivo response of the hepatic microcirculation to endothelin after remote trauma.
    Baveja R; Ashburn J; Yokoyama Y; Zhang JX; Clemens MG; Huynh T
    Shock, 09 Jun. 2001, No invitation
    Poster presentation, Domestic conference
  • Altered vascular regulation in the hepatic portal circulation in fibrosis: role of nitric oxide and carbon monoxide.
    Yokoyama Y; Baveja R; Sonin N; Clemens MG; Zhang JX
    FASEB, 31 Mar. 2001, No invitation
    Poster presentation, International conference
  • Hepatic arterial flow as the primary blood supply feeding sinusoids in partial portal vein ligation (PPVL) induced portal hypertension.
    Yokoyama Y; Wawrzyniak A; Baveja R; Sonin N; Clemens MG; Zhang JX
    FASEB, 31 Mar. 2001, No invitation
    Oral presentation, Domestic conference
  • Hepatic vascular response to elevated intraperitoenal pressure in the rat.
    Yokoyama Y; Alterman D; Baveja R; Zhang JX; Clemens MG
    FASEB, 31 Mar. 2001, No invitation
    Poster presentation, Domestic conference
  • Remote trauma sensitizes hepatic microcirculation to endothelin: a potential mechanism for enhanced injury in sequential stresses.
    Baveja R; Ashburn J; Yokoyama Y; Sonin N; Zhang JX; Clemens MG; Huynh T
    Surgical Infection Society, 2001, No invitation
    Oral presentation, Domestic conference
  • Low volume resuscitation exacerbates hepatic vascular stress gene dependent microvascular dysfunction in sepsis.
    Baveja R; Kresge N; Yokoyama Y; Sonin N; Zhang JX; Clemens MG; Huyng T
    34th Annual Meeting for the Association of Academic Surgenons, Nov. 2000, No invitation
    Poster presentation, International conference
  • Shunting of hepatic microcirculation after polymicrobial sepsis.
    Baveja R; Kresge N; Yokoyama Y; Sonin N; Zhang JX; Clemens MG; Huynh T
    American College of Surgeon Surgical Forum, Oct. 2000, American College of Surgeon, No invitation
    Oral presentation, Domestic conference
  • Changes in expression of endothelin receptor subtypes in partial portal vein ligation-induced portal hypertension.
    Yokoyama Y; Baveja R; Sonin N; Clemens MG; Zhang JX
    FASEB, 15 Apr. 2000, No invitation
    Poster presentation, Domestic conference
  • Hyporesponse of hepatic microcirculation to endothelin in sepsis.
    Baveja R; Kresge N; Yokoyama Y; Zhang JX; Huynh T; Clemens MG
    FASEB, 15 Apr. 2000, No invitation
    Oral presentation, Domestic conference
  • Expression of vasoregulatory genes in the liver during progression of cirrhosis.
    Baveja R; X Bian; Yokoyama Y; Kresge N; Sonin N; Clemens MG; Zhang JX
    FASEB, 15 Apr. 2000, No invitation
    Poster presentation, International conference
  • Functional role of endothelin receptor subtype distribution in endotoxemia.
    Yokoyama Y; Baveja R; Sonin N; Nakanishi K; JX Zhang; Clemens MG
    Shock, 03 Mar. 2000, No invitation
    Poster presentation, Domestic conference
  • Effects of fluid resuscitation on the pattern of vascular gene expression during abdominal sepsis.
    Baveja R; Kresge N; Yokoyama Y; Sonin N; Zhang JX; Clemens MG
    Shock, 03 Mar. 2000, No invitation
    Poster presentation, Domestic conference
  • Intermittent hypoxia induces vasoregulatory gene expression.
    Sonin N; Yokoyama Y; Zhang JX; Clemens MG
    Shock, 03 Mar. 2000, No invitation
    Poster presentation, Domestic conference
  • LPS-induced imbalanced expression of hepatic vascular stress genes in cirrhosis: mechanism of increased susceptibility to endotoxemia.
    Baveja R; Yokoyama Y; Bian X; Sonin N; Clemens MG; Zhang JX
    Shock, 03 Mar. 2000, No invitation
    Oral presentation, Domestic conference
  • Endothelin B receptors modulate hepatic metabolic response in endotoxin primed rats.
    Baveja R; Harding D; Yokoyama Y; Sonin N; Zhang JX; Clemens MG
    Shock, 03 Mar. 2000, No invitation
    Poster presentation, Domestic conference
  • Microheterogeneity of liver PO2 and reduced pyridine nucleotide in response to Endothelin in vivo.
    Baveja R; Sonin N; Yokoyama Y; Clemens MG; Zhang J
    FASEB, 1999, No invitation
    Oral presentation, Domestic conference
  • Effect of endotoxin on expression of vascular stress genes in liver cirrhosis.
    Smilovichi S; Baveja R; Sonin N; Yokoyama Y; Clemens MG; Zhang J
    FASEB, 1999, No invitation
    Oral presentation, Domestic conference
  • Hepatic enothelin subtype expression in endotoxin treated rat.
    Yokoyama Y; Baveja R; Sonin N; Nakanishi K; Zhang J; Clemens MG
    FASEB, 1999, No invitation
    Poster presentation, Domestic conference
  • Microheterogeneity of liver PO2 in response to Endothelin-1: exacerbation by LPS priming.
    Bauer M; Bauer I; Sonin N; Kresge N; Baveja R; Harding D; Yokoyama Y; Zhang J; Clemens MG
    Fourth International Shock Congress, 1999, No invitation
    Oral presentation, International conference
  • Expression and localization of endothelin B receptors in LPS priming.
    Yokoyama Y; Baveja R; Sonin N; Zhang J; Clemens MG
    Fourth International Shock Congress, 1999, No invitation
    Poster presentation, Domestic conference
  • Functional significance of endothelin-B receptor expression in endotoxemia.
    Bauer M; Bauer I; Sonin N; Kresge N; Baveja R; Harding D; Yokoyama Y; Zhang J; Clemens MG
    Fourth International Shock Congress, 1999, No invitation
    Poster presentation, Domestic conference
  • Differential expression of vascular stress genes in hepatocellular injury induced by following liver cirrhosis.
    Bauer I; Sonin N; Bian X; Kresge N; Baveja R; Yokoyama Y; Bauer M; Clemens MG; Zhang J
    Fourth International Shock Congress, 1999, No invitation
    Poster presentation, Domestic conference
  • Microheterogeneity of liver PO2 and redox potential in response to endothelin in vivo.
    Baveja R; Zhang J; Yokoyama Y; Sonin N; Clemens MG
    International Conference of Hepatic and Splanchnic Circulation in Health and Diseases, 1999, No invitation
    Oral presentation, Domestic conference
  • Effect of Bosentan on hepatic microcirculatory perfusion in rat biliary cirrhosis: evidence for a role of endothelin in hemodynamic abnormalities of liver cirrhosis.
    Baveja R; Kresge N; Bin X; Yokoyama Y; Sonin N; Clemens MG; Zhang J
    American Association for the Study of Liver Diseases, 1999, No invitation
    Poster presentation, Domestic conference
  • Altered Endothelin-B receptor expression and response in hepatic injury after ischemia / reperfusion.
    Yokoyama Y; Baveja R; Sonin N; Nakanishi K; Zhang J; Clemens MG
    American Association for the Study of Liver Diseases, 1999, No invitation
    Poster presentation, Domestic conference
  • Expression of vasoregulatory genes in the liver during progression of liver cirrhosis.
    Baveja R; Bin X; Yokoyama Y; Sonin N; Clemens MG; Zhang J
    American Association for the Study of Liver Diseases, 1999, No invitation
    Poster presentation, Domestic conference
  • Neovascularization of hepatic arterioles in partial portal vein ligation induced portal hypertension: a novel mechanism of chronic regulation in hepatic blood flow.
    Yokoyama Y; Baveja R; Sonin N; Clemens MG; Zhang J
    American Association for the Study of Liver Diseases, 1999, No invitation
    Oral presentation, International conference
  • Reciprocal changes in expression of vascular stress genes in hepatic parenchymal and nonparenchymal cells in response to endotoxin.
    Baveja R; Smilovichi S; Sonin N; Yokoyama Y; Clemens MG; Zhang J
    American Association for the Study of Liver Diseases, 1998, No invitation
    Poster presentation, Domestic conference
  • Reciprocal changes in expression of vascular stress genes in hepatic parenchymal and nonparenchymal cells in response to endotoxin.
    Sonin N; Baveja R; Yokayama Y; Zhang J; Clemens MG
    American Association for the Study of Liver Diseases, 1998, No invitation
    Poster presentation, Domestic conference

Research Themes

  • TLR7アプタマーによる内因性Danger Signalの制御と新規治療法の開発
    基盤研究(C)
    Jul. 2013 - Jun. 2016
    上原圭介, 上原圭介, 日本学術振興会, 日本学術振興会
  • 乳癌におけるChromothripsis変異を標的にした新規治療法の開発
    基盤研究(C)
    Jul. 2013 - Jun. 2016
    角田伸行, 角田伸行, 日本学術振興会, 日本学術振興会
  • 分子進化の概念に基づく新規遺伝子の探索と機能解析
    萌芽研究
    Jul. 2013 - Jun. 2016
    日本学術振興会, 日本学術振興会
  • 新規セリンスレオニンキナーゼ阻害剤による胆管 癌・膵癌治療法の開発
    基盤研究(B)
    Jul. 2012 - Jun. 2016
    梛野正人, 梛野正人, 日本学術振興会, 日本学術振興会
  • 分子進化の概念に基づく新規遺伝子の探索と機能解析
    萌芽研究
    Apr. 2013 - Mar. 2016
    日本学術振興会, 日本学術振興会
  • 肝虚血再潅流障害における分枝鎖アミノ酸の新規分子機構の探索
    基盤研究(C)
    Jul. 2013 - Jun. 2015
    菅原元, 菅原元, 日本学術振興会, 日本学術振興会
  • 膵癌における新規治療抵抗性遺伝子の探索とその阻害剤による治療法の開発
    基盤研究(C)
    Jul. 2012 - Jun. 2015
    國料俊男, 國料俊男, 日本学術振興会, 日本学術振興会
  • 肝切除時におけるリアルタイム肝機能モニタリングシステムの開発と臨床応用
    萌芽研究
    Jul. 2012 - Jun. 2014
    梛野正人, 梛野正人, 日本学術振興会, 日本学術振興会
  • 食道癌に対する相互マシンラーニング法によるHedgehog新規阻害剤の開発
    基盤研究(C)
    Jul. 2011 - Jun. 2014
    深谷昌秀, 深谷昌秀, 日本学術振興会, 日本学術振興会
  • 癌における細胞老化関連遺伝子の探索と臨床応用
    基盤研究(C)
    Jul. 2011 - Jun. 2014
    伊神剛, 伊神剛, 日本学術振興会, 日本学術振興会
  • 化学療法関連肝障害の外科手術への影響とその病態生理の解明
    基盤研究(C)
    Jul. 2012 - Jun. 2013
    吉岡裕一郎, 吉岡裕一郎, 日本学術振興会, 日本学術振興会
  • 大腸癌 microscopic abscess における網羅的遺伝子解析とその結果に基づく新規癌転移抑制療法の開発
    基盤研究(C)
    Jul. 2010 - Jun. 2012
    上原圭介, 上原圭介, 日本学術振興会, 日本学術振興会
  • 微小転移における網羅的遺伝子解析とその結果に基づく新規癌転移抑制療法の開発
    基盤研究(C)
    Jul. 2010 - Jun. 2012
    角田伸行, 角田伸行, 日本学術振興会, 日本学術振興会
  • Nek2を標的にした包括的癌治療法の開発とそのトランスレーショナルリサーチ
    基盤研究(A)
    Jul. 2008 - Jun. 2012
    二村雄次, 二村雄次, 日本学術振興会, 日本学術振興会
  • GGTトランスジェニックマウスを用いた肝虚血/再潅流障害メカニズムの解明
    基盤研究(C)
    Jul. 2009 - Jun. 2011
    菅原元; 横山幸浩; 國料俊男; 梛野正人, 菅原元; 横山幸浩; 國料俊男; 梛野正人, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants
  • 急性胆管閉塞にともなう肝障害におけるPPARgammaの役割について
    基盤研究(C)
    Jul. 2008 - Jun. 2010
    伊神剛, 伊神剛, 日本学術振興会, 日本学術振興会
  • 複数の癌特異的遺伝子を標的にした分子標的治療の開発
    基盤研究(C)
    Jul. 2008 - Jun. 2010
    國料俊男, 國料俊男, 日本学術振興会, 日本学術振興会
  • 肝再生におけるカルシトニンの役割とその分子機構
    基盤研究(C)
    Jul. 2008 - Jun. 2010
    横山幸浩, 横山幸浩, 日本学術振興会, 日本学術振興会, Principal investigator
  • 肝門部胆管癌からの胆管癌幹細胞の分離と網羅的遺伝子解析に基づく分子標的治療の開発
    基盤研究(B)
    Jul. 2007 - Jun. 2010
    梛野正人; 二村雄次; 國料俊男, 梛野正人; 二村雄次; 國料俊男, 日本学術振興会, 日本学術振興会
  • 胆道癌におけるHegdehogシグナル系の発現解析
    基盤研究(C)
    Jul. 2007 - Jun. 2009
    深谷昌秀; 二村雄次; 梛野正人; 安部哲也; 横山幸浩, 深谷昌秀; 二村雄次; 梛野正人; 安部哲也; 横山幸浩, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants
  • 慢性腎不全下における肝切除後肝再生のメカニズムについて
    基盤研究(C)
    Jul. 2007 - Jun. 2009
    西尾秀樹; 二村雄次; 梛野正人; 横山幸浩; 安部哲也, 西尾秀樹; 二村雄次; 梛野正人; 横山幸浩; 安部哲也, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants
  • 胆管閉塞時にみられるパイエル板萎縮のメカニズムについて
    基盤研究(C)
    Jul. 2006 - Jun. 2007
    横山幸浩; 二村雄次; 梛野正人; 安部哲也; 西尾秀樹, 横山幸浩; 二村雄次; 梛野正人; 安部哲也; 西尾秀樹, 日本学術振興会, 日本学術振興会, Principal investigator
  • 血管内皮伸展刺激に着目した肝再生メカニズムに関する基礎実験的研究
    基盤研究(C)
    Jul. 2005 - Jun. 2007
    日本学術振興会, 日本学術振興会
  • 胆管細胞癌の網羅的遺伝子解析とそれに基づく分子標的制癌療法の開発
    基盤研究(A)
    Jul. 2004 - Jun. 2007
    二村雄次; 梛野正人; 小田高司; 横山幸浩, 二村雄次; 梛野正人; 小田高司; 横山幸浩, 日本学術振興会, 日本学術振興会, Coinvestigator not use grants

Industrial Property Rights

  • 特願 2014-147173, 膵液漏の予防及び治療
    國料俊男, 横山幸浩, 山本徳則, 柴田玲
  • 2013-221492, 内毒素による臓器不全予防剤
    横山幸浩, 國料俊男
  • PCT/JP2011/077851, Device for diagnosing condition of liver and method of examing condition of liver
    Yukihiro Yokoyama, Toshio Kokuryo
  • 2010-275543, 肝臓の状態を診断する装置及び肝臓の状態を検査する方法
    横山幸浩, 國料俊男, 中川陽史