Microbiology and Immunology | Assistant Professor |
Profile
Research area
ウイルス学Main academic activities
日本ウイルス学会
日本細菌学会Main research topic
パラミクソウイルスの自然免疫逃避機構
Paper
- Human metapneumovirus M2-2 protein inhibits RIG-I signaling by preventing TRIM25-mediated RIG-I ubiquitination
Yukie Tanaka; Naoko Morita; Yoshinori Kitagawa; Bin Gotoh; Takayuki Komatsu
Frontiers in Immunology, Aug. 2022
13, 10.3389/fimmu.2022.970750 - SeV C Protein Plays a Role in Restricting Macrophage Phagocytosis by Limiting the Generation of Intracellular Double-Stranded RNA
Naoko Morita; Yukie Tanaka; Kenji Takeuchi; Yoshinori Kitagawa; Ryusuke Sakuma; Naoki Koide; Takayuki Komatsu
Frontiers in Microbiology, Feb. 2022
13, 10.3389/fmicb.2022.780534 - Sendai virus C protein affects macrophage function, which plays a critical role in modulating disease severity during Sendai virus infection in mice.
Ryusuke Sakuma; Naoko Morita; Yukie Tanaka; Naoki Koide; Takayuki Komatsu
Microbiology and immunology, Dec. 2021
10.1111/1348-0421.12956 - Screening siRNAs against host glycosylation pathways to develop novel antiviral agents against hepatitis B virus.
Kiyoaki Ito; Kiyohiko Angata; Atsushi Kuno; Akinori Okumura; Kazumasa Sakamoto; Rieko Inoue; Naoko Morita; Koichi Watashi; Takaji Wakita; Yasuhito Tanaka; Masaya Sugiyama; Masashi Mizokami; Masashi Yoneda; Hisashi Narimatsu
Hepatology research : the official journal of the Japan Society of Hepatology, Oct. 2020
50(10), 1128, 1140, 10.1111/hepr.13552 - Sendai virus V protein decreases nitric oxide production by inhibiting RIG-I signaling in infected RAW264.7 macrophages.
Naoko Morita; Yukie Tanaka; Erdenezaya Odkhuu; Yoshikazu Naiki; Takayuki Komatsu; Naoki Koide
Microbes and infection, Sep. 2020
22(8), 322, 330, 10.1016/j.micinf.2020.01.005 - Phospholipase A2 from bee venom increases poly(I:C)-induced activation in human keratinocytes.
Akina Nakashima; Susumu Tomono; Tatsuya Yamazaki; Masanori Inui; Naoko Morita; Isao Ichimonji; Hidekazu Takagi; Fumiaki Nagaoka; Misako Matsumoto; Yasuhiko Ito; Takeshi Yanagishita; Kensuke Miyake; Daisuke Watanabe; Sachiko Akashi-Takamura
International immunology, May 2020
32(6), 371, 383, 10.1093/intimm/dxaa005 - Sendai Virus V Protein Inhibits the Secretion of Interleukin-1β by Preventing NLRP3 Inflammasome Assembly.
Takayuki Komatsu; Yukie Tanaka; Yoshinori Kitagawa; Naoki Koide; Yoshikazu Naiki; Naoko Morita; Bin Gotoh; Takashi Yokochi
Journal of virology, Oct. 2018
92(19), 10.1128/JVI.00842-18 - Sendai virus C protein limits NO production in infected RAW264.7 macrophages.
Erdenezaya Odkhuu; Takayuki Komatsu; Naoki Koide; Yoshikazu Naiki; Kenji Takeuchi; Yukie Tanaka; Bilegtsaikhan Tsolmongyn; Ulziisaikhan Jambalganiin; Naoko Morita; Tomoaki Yoshida; Bin Gotoh; Takashi Yokochi
Innate immunity, Oct. 2018
24(7), 430, 438, 10.1177/1753425918796619 - Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection.
Tatsuya Yamazaki; Maria Nagashima; Daisuke Ninomiya; Akira Ainai; Akira Fujimoto; Isao Ichimonji; Hidekazu Takagi; Naoko Morita; Kenta Murotani; Hideki Hasegawa; Joe Chiba; Sachiko Akashi-Takamura
Frontiers in immunology, 2018
9, 47, 47, 10.3389/fimmu.2018.00047 - C4b-binding protein negatively regulates TLR4/MD-2 response but not TLR3 response.
Naoko Morita; Tatsuya Yamazaki; Yusuke Murakami; Ryutaro Fukui; Ikuko Yamai; Isao Ichimonji; Akina Nakashima; Fumiaki Nagaoka; Hidekazu Takagi; Kensuke Miyake; Sachiko Akashi-Takamura
FEBS letters, Jun. 2017
591(12), 1732, 1741, 10.1002/1873-3468.12693 - C4b binding protein negatively regulates TLR1/2 response.
Naoko Morita; Ikuko Yamai; Koichiro Takahashi; Yutaka Kusumoto; Takuma Shibata; Toshihiko Kobayashi; Mayumi I Nonaka; Isao Ichimonji; Hidekazu Takagi; Kensuke Miyake; Sachiko A Takamura
Innate immunity, Jan. 2017
23(1), 11, 19, 10.1177/1753425916672312 - Inflammatory responses increase secretion of MD-1 protein.
Richard Thomas Jennings; Erdenezaya Odkhuu; Akina Nakashima; Naoko Morita; Toshihiko Kobayashi; Ikuko Yamai; Miyako Tanaka; Takayoshi Suganami; Sanae Haga; Michitaka Ozaki; Yasuharu Watanabe; Yoshinori Nagai; Kiyoshi Takatsu; Takane Kikuchi-Ueda; Isao Ichimonji; Yoshihiro Ogawa; Hidekazu Takagi; Tatsuya Yamazaki; Kensuke Miyake; Sachiko Akashi-Takamura
International immunology, Oct. 2016
28(10), 503, 512 - CLEC4M-positive and CD81-negative Huh7 cells are not susceptible to JFH-1 HCVcc infection but mediate transinfection.
Mariko Ishibashi; Naoko Morita; Chisato Nomura-Kawaguchi; Yohko Shimizu; Takaji Wakita; Mariko Esumi
Archives of virology, Nov. 2014
159(11), 2949, 55, 10.1007/s00705-014-2150-z
MISC
- 補体制御因子C4BPはTLR4/MD‐2応答も制御する
高村祥子; 森田奈央子; 山崎達也
日本エンドトキシン・自然免疫研究会プログラム・抄録集, 2017, Not reviewed, No invitation
23rd, 15 - TLRの制御機構と新規制御因子について
森田 奈央子; 高村 祥子
エンドトキシン・自然免疫研究, Nov. 2016, Not reviewed, No invitation
19, 1, 5
Research Themes
- モノネガウイルスに保存された抗インターフェロン機構の解明と治療薬の研究
基盤研究(C)
愛知医科大学
01 Apr. 2023 - 31 Mar. 2026
小松 孝行; 田中 幸枝; 森田 奈央子, 小松 孝行; 田中 幸枝; 森田 奈央子, 日本学術振興会, 日本学術振興会 - 抗インフラマソーム能欠失型ウイルスを利用した新しいウイルス予防・治療法の研究
基盤研究(C)
愛知医科大学
01 Apr. 2020 - 31 Mar. 2023
小松 孝行; 田中 幸枝; 森田 奈央子, 小松 孝行; 田中 幸枝; 森田 奈央子, 日本学術振興会, 日本学術振興会
