matsushita natsuki
Institute of Comprehensive Medical Research  | Associate Professor |
| Institute of Comprehensive Medical Research | Chairperson |
| Biology |
Profile
Research area
神経科学
分子生物学
動物分子工学Main lectures
細胞生物学
分子発生学
行動科学Graduating school
名古屋大学農学部農芸化学科（1989年）Final Education
名古屋大学大学院農学研究科（1994年）Previous workplace
福島県立医科大学医学部（1999年11月～2002年8月）
愛知県心身障害者コロニー発達障害研究所（2003年8月～2006年3月）
愛媛大学大学院医学系研究科（2006年4月～2015年8月）Study abroad experience
カリフォルニア大学サンディエゴ校（米国）（2001年9月～2002年8月）Main academic activities
日本神経科学会
日本分子生物学会
日本生化学会Main research topic
遺伝子改変ウイルスベクター技術の開発と細胞機能解析への応用
ゲノム編集技術による生体機能解析と細胞治療への応用
中枢カテコールアミン神経回路の機能発達Self-introduction
生物学紹介ホームページはhttps://www.take-lab.org
Research Keyword
Paper
- Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia.
Hiroyuki Neyama; Yuping Wu; Yuka Nakaya; Shigeki Kato; Tomoko Shimizu; Tsuyoshi Tahara; Mika Shigeta; Michiko Inoue; Kazunari Miyamichi; Natsuki Matsushita; Tomoji Mashimo; Yoshiki Miyasaka; Yi Dai; Koichi Noguchi; Yasuyoshi Watanabe; Masayuki Kobayashi; Kazuto Kobayashi; Yilong Cui
Science advances, Jan. 2025, Reviewed
11(3), eadp8494, 10.1126/sciadv.adp8494 - Protocol for highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence in rodents.
Natsuki Matsushita; Shigeki Kato; Kayo Nishizawa; Masateru Sugawara; Kosei Takeuchi; Yoshiki Miyasaka; Tomoji Mashimo; Kazuto Kobayashi
STAR protocols, Oct. 2023, Reviewed
4(4), 102667, 102667, 10.1016/j.xpro.2023.102667 - Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts.
Atsuko Honda; Motohiro Nozumi; Yasuyuki Ito; Rie Natsume; Asami Kawasaki; Fubito Nakatsu; Manabu Abe; Haruki Uchino; Natsuki Matsushita; Kazutaka Ikeda; Makoto Arita; Kenji Sakimura; Michihiro Igarashi
Cell reports, Oct. 2023, Reviewed
113195, 113195, 10.1016/j.celrep.2023.113195 - Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways.
Alain Rios; Satoshi Nonomura; Shigeki Kato; Junichi Yoshida; Natsuki Matsushita; Atsushi Nambu; Masahiko Takada; Riichiro Hira; Kazuto Kobayashi; Yutaka Sakai; Minoru Kimura; Yoshikazu Isomura
Communications biology, Sep. 2023, Reviewed, No invitation
6(1), 914, 914, 10.1038/s42003-023-05288-x - Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence
Natsuki Matsushita; Shigeki Kato; Kayo Nishizawa; Masateru Sugawara; Kosei Takeuchi; Yoshiki Miyasaka; Tomoji Mashimo; Kazuto Kobayashi
Cell Reports Methods, Feb. 2023, Reviewed
3(2), 100393, 10.1016/j.crmeth.2022.100393 - Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology
Natsuki Matsushita; Kayo Nishizawa; Shigeki Kato; Yoshio Iguchi; Ryoji Fukabori; Kosei Takeuchi; Yoshiki Miyasaka; Tomoji Mashimo; Kazuto Kobayashi
Journal of Neuroscience Methods, Nov. 2022, Reviewed
381, 109707, 10.1016/j.jneumeth.2022.109707 - Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor.
Masayuki Nakano; Motokazu Koga; Tatsuo Hashimoto; Natsuki Matsushita; Daiki Masukawa; Yusuke Mizuno; Hiraku Uchimura; Ryo Niikura; Tomoyuki Miyazaki; Fumio Nakamura; Suo Zou; Takahiro Shimizu; Motoaki Saito; Kouichi Tamura; Takahisa Goto; Yoshio Goshima
Journal of pharmacological sciences, Feb. 2022, Reviewed
148(2), 214, 220, 10.1016/j.jphs.2021.11.008 - Combi-CRISPR: combination of NHEJ and HDR provides efficient and precise plasmid-based knock-ins in mice and rats.
Kazuto Yoshimi; Yuichiro Oka; Yoshiki Miyasaka; Yuko Kotani; Misato Yasumura; Yoshihiro Uno; Kosuke Hattori; Arisa Tanigawa; Makoto Sato; Manami Oya; Kazuhiro Nakamura; Natsuki Matsushita; Kazuto Kobayashi; Tomoji Mashimo
Human genetics, Jul. 2020, Reviewed, No invitation
140(2), 277, 287, 10.1007/s00439-020-02198-4 - Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line.
Arisa Mitani; Takeshi Kobayashi; Yasuhito Hayashi; Natsuki Matsushita; Sachi Matsushita; Saori Nakao; Naoko Takahira; Atsushi Shiraishi; Yuichi Ohashi
PloS one, 2019, Reviewed, No invitation
14(9), e0222454, 10.1371/journal.pone.0222454 - Extracellular Signals Induce Glycoprotein M6a Clustering of Lipid Rafts and Associated Signaling Molecules
Atsuko Honda; Yasuyuki Ito; Kazuko Takahashi-Niki; Natsuki Matsushita; Motohiro Nozumi; Hidenori Tabata; Kosei Takeuchi; Michihiro Igarashi
JOURNAL OF NEUROSCIENCE, Apr. 2017, Reviewed, No invitation
37(15), 4046, 4064, 10.1523/JNEUROSCI.3319-16.2017 - Conformational plasticity of JRAB/MICAL-L2 provides "law and order" in collective cell migration
Ayuko Sakane; Shin Yoshizawa; Masaomi Nishimura; Yuko Tsuchiya; Natsuki Matsushita; Kazuhisa Miyake; Kazuki Horikawa; Issei Imoto; Chiharu Mizuguchi; Hiroyuki Saito; Takato Ueno; Sachi Matsushita; Hisashi Haga; Shinji Deguchi; Kenji Mizuguchi; Hideo Yokota; Takuya Sasaki
MOLECULAR BIOLOGY OF THE CELL, Oct. 2016, Reviewed, No invitation
27(20), 3095, 3108, 10.1091/mbc.E16-05-0332 - Rotation is the primary motion of paired human epidermal keratinocytes
Sota Tate; Matome Imai; Natsuki Matsushita; Emi K. Nishimura; Shigeki Higashiyama; Daisuke Nanba
JOURNAL OF DERMATOLOGICAL SCIENCE, Sep. 2015, Reviewed, No invitation
79(3), 194, 202, 10.1016/j.jdermsci.2015.05.008 - Arkadia enhances BMP signalling through ubiquitylation and degradation of Smad6
Yutaro Tsubakihara; Atsuhiko Hikita; Shin Yamamoto; Sachi Matsushita; Natsuki Matsushita; Yusuke Oshima; Keiji Miyazawa; Takeshi Imamura
JOURNAL OF BIOCHEMISTRY, Jul. 2015, Reviewed, No invitation
158(1), 61, 71, 10.1093/jb/mvv024 - Cell motion predicts human epidermal stemness
Daisuke Nanba; Fujio Toki; Sofa Tate; Matome Imai; Natsuki Matsushita; Ken Shiraishi; Koji Sayama; Hiroshi Toki; Shigeki Higashiyama; Yann Barrandon
JOURNAL OF CELL BIOLOGY, Apr. 2015, Reviewed, No invitation
209(2), 305, 315, 10.1083/jcb.201409024 - High-throughput synthesis of stable isotope-labeled transmembrane proteins for targeted transmembrane proteomics using a wheat germ cell-free protein synthesis system
Nobuaki Takemori; Ayako Takemori; Kazuhiro Matsuoka; Ryo Morishita; Natsuki Matsushita; Masato Aoshima; Hiroyuki Takeda; Tatsuya Sawasaki; Yaeta Endo; Shigeki Higashiyama
MOLECULAR BIOSYSTEMS, 2015, Reviewed, No invitation
11(2), 361, 365, 10.1039/c4mb00556b - Enhanced flexibility of place discrimination learning by targeting striatal cholinergic interneurons
Kana Okada; Kayo Nishizawa; Ryoji Fukabori; Nobuyuki Kai; Akira Shiota; Masatsugu Ueda; Yuji Tsutsui; Shogo Sakata; Natsuki Matsushita; Kazuto Kobayashi
NATURE COMMUNICATIONS, May 2014, Reviewed, No invitation
5, 3778, 10.1038/ncomms4778 - Chondroitin sulphate N-acetylgalactosaminyl-transferase-1 inhibits recovery from neural injury
Kosei Takeuchi; Nozomu Yoshioka; Susumu Higa Onaga; Yumi Watanabe; Shinji Miyata; Yoshino Wada; Chika Kudo; Masayasu Okada; Kentaro Ohko; Kanako Oda; Toshiya Sato; Minesuke Yokoyama; Natsuki Matsushita; Masaya Nakamura; Hideyuki Okano; Kenji Sakimura; Hitoshi Kawano; Hiroshi Kitagawa; Michihiro Igarashi
NATURE COMMUNICATIONS, Nov. 2013, Reviewed, No invitation
4, 2740, 10.1038/ncomms3740 - Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins
Ayuko Sakane; Ahmed Alamir Mahmoud Abdallah; Kiyoshi Nakano; Kazufumi Honda; Toshio Kitamura; Issei Imoto; Natsuki Matsushita; Takuya Sasaki
GENES TO CELLS, Sep. 2013, Reviewed, No invitation
18(9), 810, 822, 10.1111/gtc.12078 - Human Antigen R-mediated mRNA Stabilization Is Required for Ultraviolet B-induced Autoinduction of Amphiregulin in Keratinocytes
Hironao Nakayama; Shinji Fukuda; Natsuki Matsushita; Hisayo Nishida-Fukuda; Hirofumi Inoue; Yuji Shirakata; Koji Hashimoto; Shigeki Higashiyama
JOURNAL OF BIOLOGICAL CHEMISTRY, Apr. 2013, Reviewed, No invitation
288(15), 10338, 10348, 10.1074/jbc.M112.417527 - Actin filament dynamics impacts keratinocyte stem cell maintenance
Daisuke Nanba; Fujio Toki; Natsuki Matsushita; Sachi Matsushita; Shigeki Higashiyama; Yann Barrandon
EMBO MOLECULAR MEDICINE, Apr. 2013, Reviewed, No invitation
5(4), 640, 653, 10.1002/emmm.201201839 - Doxycycline-Dependent Inducible and Reversible RNA Interference Mediated by a Single Lentivirus Vector
Natsuki Matsushita; Sachi Matsushita; Satoshi Hirakawa; Shigeki Higashiyama
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Apr. 2013, Reviewed, No invitation
77(4), 776, 781, 10.1271/bbb.120917 - Actin filament dynamics impacts keratinocyte stem cell maintenance.
Daisuke Nanba; Fujio Toki; Natsuki Matsushita; Sachi Matsushita; Shigeki Higashiyama; Yann Barrandon
EMBO Mol Med, Apr. 2013, Reviewed, No invitation
5(4), 640, 653, 10.1002/emmm.201201839 - Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector
Daisuke Nanba; Natsuki Matsushita; Fujio Toki; Shigeki Higashiyama
Stem Cell Research and Therapy, 2013, Reviewed, No invitation
4(5), 127, 10.1186/scrt338 - Rab13 Small G Protein and Junctional Rab13-binding Protein (JRAB) Orchestrate Actin Cytoskeletal Organization during Epithelial Junctional Development
Ayuko Sakane; Ahmed Alamir Mahmoud Abdallah; Kiyoshi Nakano; Kazufumi Honda; Wataru Ikeda; Yumiko Nishikawa; Mitsuru Matsumoto; Natsuki Matsushita; Toshio Kitamura; Takuya Sasaki
JOURNAL OF BIOLOGICAL CHEMISTRY, Dec. 2012, Reviewed, No invitation
287(51), 42455, 42468, 10.1074/jbc.M112.383653 - Role of activation-induced cytidine deaminase in the progression of follicular lymphoma
Hisaharu Shikata; Yoshihiro Yakushijin; Natsuki Matsushita; Akira Sakai; Atsuro Sugita; Naoya Nakamura; Jun Yamanouchi; Taichi Azuma; Takaaki Hato; Masaki Yasukawa
CANCER SCIENCE, Mar. 2012, Reviewed, No invitation
103(3), 415, 421, 10.1111/j.1349-7006.2011.02186.x - Activation of epidermal growth factor receptor gene is involved in transforming growth factor-beta-mediated fibronectin expression in a chondrocyte progenitor cell line
Haruhiko Takeda; Hirofumi Inoue; Tastuhiko Kutsuna; Natsuki Matsushita; Toshiaki Takahashi; Shohei Watanabe; Shigeki Higashiyama; Haruyasu Yamamoto
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Apr. 2010, Reviewed, No invitation
25(4), 593, 600, 10.3892/ijmm_00000381 - Magnesium Deficiency Causes Loss of Response to Intermittent Hypoxia in Paraganglion Cells
Satoru Torii; Kentaro Kobayashi; Masayuki Takahashi; Kasumi Katahira; Kenji Goryo; Natsuki Matsushita; Ken-ichi Yasumoto; Yoshiaki Fujii-Kuriyama; Kazuhiro Sogawa
JOURNAL OF BIOLOGICAL CHEMISTRY, Jul. 2009, Reviewed, No invitation
284(28), 19077, 19089, 10.1074/jbc.M109.004424 - Fate of transient catecholaminergic cell types revealed by site-specific recombination in transgenic mice.
Natsuki Matsushita; Kenta Kobayashi; Jun-ichi Miyazaki; Kazuto Kobayashi
Journal of neuroscience research, Oct. 2004, Reviewed, No invitation
78(1), 7, 15, 10.1002/jnr.20229 - A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor-Arnt heterodimer
K Sogawa; K Numayama-Tsuruta; T Takahashi; N Matsushita; C Miura; J Nikawa; O Gotoh; Y Kikuchi; Y Fujii-Kuriyama
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Jun. 2004, Reviewed, No invitation
318(3), 746, 755, 10.1016/j.bbrc.2004.04.090 - Identification of GABA(A) receptor subunit variants in midbrain dopaminergic neurons
H Okada; N Matsushita; K Kobayashi; K Kobayashi
JOURNAL OF NEUROCHEMISTRY, Apr. 2004, Reviewed, No invitation
89(1), 7, 14, 10.1111/j.1471-4159.2004.02271.x - Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase
K Kobayashi; M Takahashi; N Matsushita; J Miyazaki; M Koike; H Yaginuma; N Osumi; K Kaibuchi; K Kobayashi
JOURNAL OF NEUROSCIENCE, Apr. 2004, Reviewed, No invitation
24(14), 3480, 3488, 10.1523/JNEUROSCI.0295-04.2004 - Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function.
Hiromi Sano; Yasunobu Yasoshima; Natsuki Matsushita; Takeshi Kaneko; Kenji Kohno; Ira Pastan; Kazuto Kobayashi
The Journal of neuroscience : the official journal of the Society for Neuroscience, Oct. 2003, Reviewed, No invitation
23(27), 9078, 88 - Dynamics of tyrosine hydroxylase promoter activity during midbrain dopaminergic neuron development.
Natsuki Matsushita; Hideki Okada; Yasunobu Yasoshima; Kazuaki Takahashi; Kazutoshi Kiuchi; Kazuto Kobayashi
Journal of neurochemistry, Jul. 2002, Reviewed, No invitation
82(2), 295, 304, 10.1046/j.1471-4159.2002.00972.x - Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene
H Ishiguro; K Yamada; H Sawada; K Nishii; N Ichino; M Sawada; Y Kurosawa; N Matsushita; K Kobayashi; J Goto; H Hashida; N Masuda; Kanazawa, I; T Nagatsu
JOURNAL OF NEUROSCIENCE RESEARCH, Aug. 2001, Reviewed, No invitation
65(4), 289, 297, 10.1002/jnr.1153 - Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons
K Sawamoto; N Nakao; K Kobayashi; N Matsushita; H Takahashi; K Kakishita; A Yamamoto; T Yoshizaki; T Terashima; F Murakami; T Itakura; H Okano
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, May 2001, Reviewed, No invitation
98(11), 6423, 6428, 10.1073/pnas.111152398 - Promoter analysis and characteristics of the 5′-untranslated region of the mouse glial cell line-derived neurotrophic factor gene
Mikiei Tanaka; Sachiko Ito; Natsuki Matsushita; Nozomu Mori; Kazutoshi Kiuchi
Molecular Brain Research, Dec. 2000, Reviewed, No invitation
85, 91, 102, 10.1016/S0169-328X(00)00250-3 - Modest neuropsychological deficits caused by reduced noradrenaline metabolism in mice heterozygous for a mutated tyrosine hydroxylase gene
K Kobayashi; Y Noda; N Matsushita; K Nishii; H Sawada; T Nagatsu; D Nakahara; R Fukabori; Y Yasoshima; T Yamamoto; M Miura; M Kano; T Mamiya; Y Miyamoto; T Nabeshima
JOURNAL OF NEUROSCIENCE, Mar. 2000, Reviewed, No invitation
20(6), 2418, 2426 - Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission
K Nishii; N Matsushita; H Sawada; H Sano; Y Noda; T Mamiya; T Nabeshima; Nagatsu, I; T Hata; K Kiuchi; H Yoshizato; K Nakashima; T Nagatsu; K Kobayashi
JOURNAL OF NEUROSCIENCE RESEARCH, Nov. 1998, Reviewed, No invitation
54(4), 450, 464, 10.1002/(SICI)1097-4547(19981115)54:4<450::AID-JNR3>3.0.CO;2-B - GFPを利用したトランスジェニックマウスにおける軸索ガイダンスのモニター系の確立
服部 祐紀; 斉藤 美知子; 松下 夏樹; 小林 和人
神経化学, Sep. 1998
37(3), 547, 547 - Prevention of dopaminergic neuron death by adeno-associated virus vector-mediated GDNF gene transfer in rat mesencephalic cells in vitro
Dong Sheng Fan; Dong Sheng Fan; Matsuo Ogawa; Kunihiko Ikeguchi; Ken Ichi Fujimoto; Masashi Urabe; Akihiro Kume; Masatoyo Nishizawa; Natsuki Matsushita; Natsuki Matsushita; Kazutoshi Kiuchi; Hiroshi Ichinose; Toshiharu Nagatsu; Gary J. Kurtzman; Imaharu Nakano; Keiya Ozawa
Neuroscience Letters, May 1998, Reviewed, No invitation
248, 61, 64, 10.1016/S0304-3940(98)00313-9 - Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF
N Matsushita; Y Fujita; M Tanaka; T Nagatsu; K Kiuchi
GENE, Dec. 1997, Reviewed, No invitation
203(2), 149, 157, 10.1016/S0378-1119(97)00506-4 - A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4
Higashiyama S; Horikawa M; Yamada K; Ichino N; Nakano N; Nakagawa T; Miyagawa J; Matsushita N; Nagatsu T; Taniguchi N; Ishiguro H
J Biochem, Sep. 1997, Reviewed, No invitation
122(3), 675, 680 - POSSIBLE FUNCTION OF AH RECEPTOR NUCLEAR TRANSLOCATOR (ARNT) HOMODIMER IN TRANSCRIPTIONAL REGULATION
K SOGAWA; R NAKANO; A KOBAYASHI; Y KIKUCHI; N OHE; N MATSUSHITA; Y FUJIIKURIYAMA
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Mar. 1995, Reviewed, No invitation
92(6), 1936, 1940, 10.1073/pnas.92.6.1936 - CHOLESTEROL-RICH VERY-LOW-DENSITY LIPOPROTEINS AND FATTY LIVER IN RATS FED POLYCHLORINATED-BIPHENYLS
H ODA; N MATSUSHITA; A HIRABAYASHI; A YOSHIDA
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Dec. 1994, Reviewed, No invitation
58(12), 2152, 2158 - HUMAN ARYLHYDROCARBON RECEPTOR - FUNCTIONAL EXPRESSION AND CHROMOSOMAL ASSIGNMENT TO 7P21
M EMA; N MATSUSHITA; K SOGAWA; T ARIYAMA; J INAZAWA; T NEMOTO; M OTA; M OSHIMURA; Y FUJIIKURIYAMA
JOURNAL OF BIOCHEMISTRY, Oct. 1994, Reviewed, No invitation
116(4), 845, 851 - INDUCTION OF CYTOCHROME P-450S AND EXPRESSION OF LIVER-SPECIFIC GENES IN RAT PRIMARY HEPATOCYTES CULTURED ON DIFFERENT EXTRACELLULAR MATRICES
N MATSUSHITA; H ODA; K KOBAYASHI; T AKAIKE; A YOSHIDA
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Aug. 1994, Reviewed, No invitation
58(8), 1514, 1516, 10.1271/bbb.58.1514 - DNA-BINDING REGULATORY FACTORS AND INDUCIBLE EXPRESSION OF THE P4501A1 GENE
K SOGAWA; N MATSUSHITA; M EMA; Y FUJIIKURIYAMA
CYTOCHROME P450, 1994, Reviewed, No invitation
75, 80 - A factor binding to the xenobiotic responsive element (XRE) of P-4501A1 gene consists of at least two helix-loop-helix proteins, Ah receptor and Arnt.
Natsuki Matsushita; Kazuhiro Sogawa; Masatsugu Ema; Akira Yoshida; Yoshiaki Fujii-Kuriyama
J. Biol. Chem., Oct. 1993, Reviewed, No invitation
Lead, 268(28), 21002, 21006 - ASCORBIC-ACID DEFICIENCY REDUCES THE LEVEL OF MESSENGER-RNA FOR CYTOCHROME-P-450 ON THE INDUCTION BY POLYCHLORINATED-BIPHENYLS
N MATSUSHITA; T KOBAYASHI; H ODA; F HORIO; A YOSHIDA
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, Aug. 1993, Reviewed, No invitation
39(4), 289, 302, 10.3177/jnsv.39.289 - CDNA CLONING AND STRUCTURE OF MOUSE PUTATIVE AH RECEPTOR
M EMA; K SOGAWA; N WATANABE; Y CHUJOH; N MATSUSHITA; O GOTOH; Y FUNAE; Y FUJIIKURIYAMA
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Apr. 1992, Reviewed, No invitation
184(1), 246, 253, 10.1016/0006-291X(92)91185-S - Nutritional Significance of Ascorbic Acid for the Metabolism of Xenobiotics and Cholesterol in ODS-and Conventional Rats
HORIO F.; MATSUSHITA N.; YOSHIDA A.
Journal of Nutritional Science and Vitaminology, 1992
38, 165, 168, 10.3177/jnsv.38.Special_165
MISC
- Leakage-repressed vectors in recombinase-dependent gene expression switch system
加藤成樹; 松下夏樹; 小林和人
日本分子生物学会年会プログラム・要旨集(Web), 2023
46th - 中枢カテコールアミン細胞選択的にCre酵素を発現する新規ノックインラットのCombi-CRISPR法による作製
松下夏樹; 西澤佳代; 深堀良二; 橋本裕美; 井口善生; 加藤成樹; 宮坂佳樹; 真下知士; 武内恒成; 小林和人
日本分子生物学会年会プログラム・要旨集(Web), 2020
43rd - In vivo regulation of chondroitin sulfate gene to recovery from spinal cord injury and brain infarction
K. Takeuchi; N. Matsushita; H. Kawano; M. Igarashi
JOURNAL OF NEUROCHEMISTRY, Aug. 2017, Not reviewed, No invitation
142, 118, 118 - 神経極性形成における4回膜貫通タンパク質-Glycoprotein M6a-のin vivo機能解析
伊藤泰行; 本多敦子; 本多敦子; 武内恒成; 松下夏樹; 五十嵐道弘; 五十嵐道弘
日本分子生物学会年会プログラム・要旨集(Web), 2016
39th - Jmjd3依存的エピジェネティック修飾に伴った脊髄アストロサイト内の複数遺伝子長期的発現変動による脊髄内疼痛感作形成機構
葛巻直子; 池上大悟; 成田道子; 松下夏樹; 五十嵐勝秀; 牛島俊和; 牛島俊和; 成田年; 成田年
Pain Research, 2015
30(2) - 非組込型レンチウイルスベクターを用いたCRISPR/Cas9システムによる高効率遺伝子ターゲティング
松下夏樹; 松下佐知; 坂根亜由子; 佐々木卓也; 今村健志; 今村健志; 今村健志
日本分子生物学会年会プログラム・要旨集(Web), 2014
37th - ヒト表皮角化幹細胞コロニー動態を集団動理学で読み解く
難波大輔; 難波大輔; 土岐富士緒; 土岐富士緒; 松下夏樹; 田手壮太; 今井統; 土岐博; 東山繁樹; 東山繁樹; BARRANDON Yann; BARRANDON Yann
再生医療, 2013
12 - RNA結合蛋白質Human antigen Rによる膜型増殖因子AmphiregulinのmRNA安定化機構の解析
福田信治; 中山寛尚; 松下夏樹; 福田尚代; 井上博文; 白方裕司; 橋本公二; 東山繁樹
生化学, 2013
85(7) - Absolute quantification method for neurotransmitter receptors in mouse brains using wheat cell-free protein synthesis and MRM mass spectrometry
N. Matsushita; N. Takemori; S. Matsushita; A. Takemori; S. Higashiyama
JOURNAL OF NEUROCHEMISTRY, Oct. 2012, Not reviewed, No invitation
123, 87, 87 - RNA結合蛋白質HuRが制御する膜型増殖因子AmphiregulinのmRNA安定化機構
福田信治; 中山寛尚; 中山寛尚; 松下夏樹; 西田(福田)尚代; 井上博文; 井上博文; 井上博文; 白方裕司; 橋本公二; 東山繁樹; 東山繁樹
日本分子生物学会年会プログラム・要旨集(Web), 2012
35th - Immunohistochemical analysis of Zbtb20 expression, a member of the BTB/POZ zinc finger family, in the mouse brain
Natsuki Matsushita; Sachi Matsushita; Shigeki Higashiyama
NEUROSCIENCE RESEARCH, 2010, Not reviewed, No invitation
68, E370, E370, 10.1016/j.neures.2010.07.1639 - マグネシウム欠乏はパラガングリオン細胞での間欠的低酸素応答の欠如を引き起こす
鳥居 暁; 小林 健太郎; 高橋 正之; 片平 香澄美; 松下 夏樹; 安元 研一; 藤井 義明; 十川 和博
日本生化学会大会プログラム・講演要旨集, Sep. 2009, Not reviewed, No invitation
82回, 3T6a, 6 - Membrane-anchored growth factors, the epidermal growth factor family: Beyond receptor ligands
Shigeki Higashiyama; Hidehiko Iwabuki; Chie Morimoto; Miki Hieda; Hirofumi Inoue; Natsuki Matsushita
CANCER SCIENCE, Feb. 2008, Not reviewed, No invitation
99(2), 214, 220, 10.1111/j.1349-7006.2007.00676.x - 慢性間欠的低酸素応答性チロシン水酸化酵素誘導に対するマグネシウム要求性に関する解析
鳥居暁; 小林健太郎; 高橋正之; 片平香澄美; 松下夏樹; 安元研一; 藤井義明; 十川和博
生化学, 2008, Not reviewed, No invitation
4P-0420 - 中脳ドーパミンニューロンの発生過程におけるチロシン水酸化酵素遺伝子プロモーターの発現特性 GFPを用いたイメージング解析
小林和人; 松下夏樹; 高橋一彰; 木内一寿
日本神経科学大会プログラム・抄録集, 2001
24th - Development of Midbrain Dopaminergic Neurons and Imaging System with Transgenic Mice Expressing GFP.
松下夏樹; 小林和人
福島医学雑誌, 2001, Not reviewed, No invitation
51(2), 95, 111 - Somatic instability of CAG repeat occurs in the HD gene knock-in mouse.
H Ishiguro; K Yamada; H Sawada; K Nishii; N Ichino; M Sawada; Y Kurosawa; N Matsushita; K Kobayashi; J Goto; Kanazawa, I; T Nagatsu
AMERICAN JOURNAL OF HUMAN GENETICS, Oct. 2000, Not reviewed, No invitation
67(4), 348, 348 - ハンチントン病モデルマウスを用いた神経病理組織学的検討
沢田浩秀; 石黒啓司; 西井一宏; 山田晃司; 松下夏樹; 小林和人; 後藤順; 金沢一郎; 永津俊治
日本神経科学大会プログラム・抄録集, 04 Sep. 2000, Not reviewed, No invitation
23rd, 226 - ハンチントン病モデルマウスを用いたCAGリピートの不安定性に関する研究
山田晃司; 石黒啓司; 西井一宏; 沢田浩秀; 小林和人; 松下夏樹; 後藤順; 金沢一郎; 永津俊治
生化学, 25 Aug. 2000, Not reviewed, No invitation
72(8), 941, 941 - イムノトキシン細胞標的法を利用した線条体ドーパミンD2受容体発現ニューロンの選択的破壊
佐野裕美; 松下夏樹; 西井一宏; 沢田浩秀; 永津俊治; 金子鋭; 中西重忠; IRA P; 小林和人
日本神経科学大会プログラム・抄録集, 2000
23rd - 生体組織より直接濃縮・分離した神経幹細胞・神経前駆細胞及びドーパミンニューロンの解析
沢本和延; 中尾直之; 垣下浩二; 山本篤世; 松下夏樹; 山口正洋; 寺島俊雄; 板倉徹; 岡野栄之
日本神経科学大会プログラム・抄録集, 2000
23rd - チロシン水酸化酵素遺伝子変異マウスにおけるノルアドレナリン神経伝達と長期記憶形成の障害
小林和人; 野田幸裕; 松下夏樹; 西井一宏; 中原大一郎; 深堀良二; 三浦正巳; 狩野方伸; 鍋島俊隆
生化学, 2000
72(8) - ハンチントン病モデルマウスにおける脳特異的CAGリピートの不安定性と病態
石黒 啓司; 山田 晃司; 澤田 浩秀; 西井 一宏; 市野 直浩; 黒澤 良和; 小林 和人; 松下 夏樹; 後藤 順; 金澤 一郎; 永津 俊治
生化学, Aug. 1999, Not reviewed, No invitation
71(8), 989, 989 - GFPとFACSを用いたドーパミン神経細胞分化過程の解析
沢本和延; 小川祐人; 松下夏樹; 山口正洋; 山本篤世; 川口綾乃; 宮田卓樹; 森憲作; 小林和人
日本分子生物学会年会プログラム・講演要旨集, 1999
22nd - ドーパミン欠損遺伝子変異マウスにおける情動行動と内分泌機能
佐野裕美; 西井一宏; 松下夏樹; 野田幸裕; 木内一寿; 吉里秀雄; 中島邦夫; 永津俊治; 小林和人
日本分子生物学会年会プログラム・講演要旨集, 1998
21st - チロシン水酸化酵素遺伝子変異マウスのノルアドレナリン代謝変動に基づく記憶・学習機能の障害
深堀良二; 野田幸裕; 松下夏樹; 永津俊治; 間宮隆吉; 中原大一郎; 三浦正己; 狩野方伸; 小林和人
日本分子生物学会年会プログラム・講演要旨集, 1998
21st - Motor Dysfunctions in Dopamine-Deficient Mice.
西井一宏; 沢田浩秀; 松下夏樹; 永津俊治; 木内一寿; 小林和人
日本分子生物学会年会プログラム・講演要旨集, 1997
20th - Dopamine defective mouse by Transgenic rescue method.
小林和人; 沢田浩秀; 西井一宏; 松下夏樹; 木内一寿; 長谷川佳代; 畑忠善; 永津俊治
日本分子生物学会年会プログラム・講演要旨集, 1996
19th - Expression and structure of a gliocyte derivation neurotrophic factor (GDNF) gene of a mouse.
松下夏樹; 藤田陽子; 木内一寿
日本分子生物学会年会プログラム・講演要旨集, 1996
19th - POLYMORPHIC FORMS OF THE AH RECEPTOR AND INDUCTION OF THE CYP1A1 GENE
Y FUJIIKURIYAMA; M EMA; J MIMURA; N MATSUSHITA; K SOGAWA
PHARMACOGENETICS, 1995, Not reviewed, No invitation
5, S149, S153, 10.1097/00008571-199512001-00018
Research Themes
- Gene and cell function dynamics underlying behavioral adaptation in response to environments
Grant-in-Aid for Transformative Research Areas (A)
Fukushima Medical University
10 Sep. 2021 - 31 Mar. 2026
小林 和人; 松下 夏樹; 瀬戸川 将, 小林 和人; 松下 夏樹; 瀬戸川 将, 日本学術振興会, Japan Society for the Promotion of Science - Regulation of ectodomian shedding by ADAM17 and remnant signaling
Grant-in-Aid for Scientific Research (B)
Ehime University
01 Apr. 2012 - 31 Mar. 2015
東山 繁樹; 福田 信治; 井上 博文; 松下 夏樹; 城 卓志, HIGASHIYAMA Shigeki; FUKUDA Shinji; INOUE Hirofumi; MATSUSHITA Natsuki; JHO Takashi, 日本学術振興会, Japan Society for the Promotion of Science - BTB-Zincフィンガー因子の多様な分子機能に見る細胞機能調節の動作原理
2008 - 2012 - 中枢カテコールアミン神経回路の発生と機能
2006 - 2010 - 神経幹細胞とニューロン分化誘導制御におけるBTB-Zincフィンガー転写抑制因子の機能解析
2006 - 2010 - レンチウイルスを利用した細胞機能及び遺伝子機能改変のための新技術の開発と応用
2008 - 2009 - Study of differentiation of midbrain dopaminergic neurons using novel cell type-specific molecules
Grant-in-Aid for Scientific Research (C)
Ehime University
2006 - 2007
松下 夏樹, MATSUSHITA Natsuki, 日本学術振興会, Japan Society for the Promotion of Science - イムノトキシン細胞標的法を利用した脳情報処理機構の解析
特定領域研究(A)
福島県立医科大学
2000 - 2001
小林 和人; 八十島 安伸; 松下 夏樹, 小林 和人; 八十島 安伸; 松下 夏樹, 日本学術振興会, 日本学術振興会 - Molecular and cellular mechanisms underlying catecholaminergic regulation of higher brain functions
Grant-in-Aid for Scientific Research (B)
Fukushima Medical University
1999 - 2001
小林 和人; 八十島 安伸; 松下 夏樹, KOBAYASHI Kazuto; YASOSHIMA Yasunobu; MATSUSHITA Natsuki, 日本学術振興会, Japan Society for the Promotion of Science - 中脳ドーパミンニューロンの発生と生存に関するマウス分子遺伝学的研究
特定領域研究(A)
福島県立医科大学
2000 - 2000
小林 和人; 松下 夏樹, 小林 和人; 松下 夏樹, 日本学術振興会, 日本学術振興会 - Molecular Mechanism of Axon Guidance during Development of Subtantia Nigra-Striatum Pathway
Grant-in-Aid for Scientific Research (C)
Fukushima Medical University
1999 - 2000
松下 夏樹; 小林 和人, MATSUSHITA Natsuki; KOBAYASHI Kazuto, 日本学術振興会, Japan Society for the Promotion of Science - GFP発現トランスジェニックマウスを利用した選択的神経細胞死の解析
特定領域研究(A)
福島県立医科大学
1999 - 1999
小林 和人; 松下 夏樹, 小林 和人; 松下 夏樹, 日本学術振興会, 日本学術振興会 - 中枢カテコールアミンニューロンをモデルにした神経回路形成のマウス遺伝学的解析
特定領域研究(A)
奈良先端科学技術大学院大学
1998 - 1998
小林 和人; 松下 夏樹, 小林 和人; 松下 夏樹, 日本学術振興会, 日本学術振興会 - カラコールアミンシグナル伝達系の脳高次機能および神経可塑性における役割の解析
特定領域研究(A)
奈良先端科学技術大学院大学
1998 - 1998
小林 和人; 松下 夏樹, 小林 和人; 松下 夏樹, 日本学術振興会, 日本学術振興会
