MIYAHARA Hiroaki
Institute for Medical Science of Aging | Professor |
| Institute for Medical Science of Aging | Chairperson |
Profile
Research area
神経病理学
小児神経学
小児科学Main lectures
小児の神経病理Graduating school
大分医科大学（2001年）Previous workplace
大分大学医学部附属病院小児科（2001年5月～2018年3月の間に約9年間勤務）
新潟大学脳研究所病理学分野（2009年4月～2011年3月）
Johns-Hopkins University, Department of Patholgy（2015年3月～2016年2月）Main academic activities
日本神経病理学会
日本脳腫瘍病理学会
日本病理学会Main research topic
１．髄芽腫を予後の良い腫瘍に変化（分化）させる因子を探求しています。
２．ミトコンドリア患者さんの脳組織を用いて、病変部位のミトコンドリアの変異率や機能を分析しています。Self-introduction
小児科医の先生方と小児疾患の神経病理について議論できる場を切望しています。小児の神経解剖の機会がありましたら、ぜひお声かけください。もちろん小児疾患に関する共同研究も大歓迎です。Hobby
最近、ギターを始めましたが独学なのでなかなか上達しません。
Member History
Award
Paper
- Correlation between clinical and neuropathological subtypes of progressive supranuclear palsy.
Ryuichi Koizumi; Akio Akagi; Yuichi Riku; Hiroaki Miyahara; Jun Sone; Fumiaki Tanaka; Mari Yoshida; Yasushi Iwasaki
Parkinsonism & related disorders, Oct. 2024
127, 106076-106076, 10.1016/j.parkreldis.2024.106076 - Clinical characteristics of Japanese patients with corticobasal degeneration.
Daisuke Tahara; Nao Tahara; Akio Akagi; Yuichi Riku; Jun Sone; Hiroaki Miyahara; Atsushi Nagai; Mari Yoshida; Yasushi Iwasaki
Journal of the neurological sciences, Sep. 2024
466, 123212-123212, 10.1016/j.jns.2024.123212 - DHCR7 links cholesterol synthesis with neuronal development and axonal integrity
Shuya Miyazaki; Nobuyuki Shimizu; Hiroaki Miyahara; Hitoshi Teranishi; ryohei umeda; Shinji Yano; Tatsuo Shimada; Hiroshi Shiraishi; Kosaku Komiya; Akira Katoh; Akihiko Yoshimura; Reiko Hanada; Toshikatsu Hanada
Biochemical and Biophysical Research Communications, Jun. 2024
10.1016/j.bbrc.2024.149932 - Hypertrophy of the inferior olivary nucleus in corticobasal degeneration: A neuropathological study
Daisuke Tahara; Nao Tahara; Akio Akagi; Yuichi Riku; Jun Sone; Hiroaki Miyahara; Atsushi Nagai; Mari Yoshida; Yasushi Iwasaki
Clinical Neuropathology, May 2024
10.5414/np301616 - Biallelic variants in LARS1 induce steatosis in developing zebrafish liver via enhanced autophagy.
Masanori Inoue; Wulan Apridita Sebastian; Shota Sonoda; Hiroaki Miyahara; Nobuyuki Shimizu; Hiroshi Shiraishi; Miwako Maeda; Kumiko Yanagi; Tadashi Kaname; Reiko Hanada; Toshikatsu Hanada; Kenji Ihara
Orphanet journal of rare diseases, May 2024
19(1), 219-219, 10.1186/s13023-024-03226-6 - 遠位尿細管性アシドーシスに伴う難聴発症のメカニズム解明
池内 真代; 清田 今日子; 宮原 弘明; 宮崎 周也; ウラン・セバスチャン; 井上 真紀; 清水 誠之; 白石 裕士; 花田 俊勝; 井原 健二
日本小児腎臓病学会雑誌, May 2024
37(Suppl.), 94-94 - A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish.
Mayo Ikeuchi; Masanori Inoue; Hiroaki Miyahara; Wulan Apridita Sebastian; Shuya Miyazaki; Takashi Takeno; Kyoko Kiyota; Shinji Yano; Hiroshi Shiraishi; Nobuyuki Shimizu; Reiko Hanada; Akihiko Yoshimura; Kenji Ihara; Toshikatsu Hanada
Biochemical and biophysical research communications, Jan. 2024
699, 149551-149551, 10.1016/j.bbrc.2024.149551 - Degeneration of olivospinal tract in the upper cervical spinal cord of multiple system atrophy patients: Reappraisal of Helweg's triangular tract.
Takashi Ando; Yuichi Riku; Akio Akagi; Hiroaki Miyahara; Takashi Uematsu; Ikuko Aiba; Jun Sone; Masahisa Katsuno; Mari Yoshida; Yasushi Iwasaki
Brain pathology (Zurich, Switzerland), Nov. 2023
e13226, 10.1111/bpa.13226 - Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation.
Hiroaki Miyahara; Chisato Tamai; Masanori Inoue; Kazuhito Sekiguchi; Daisuke Tahara; Nao Tahara; Kazuhiro Takeda; Shusei Arafuka; Hideyuki Moriyoshi; Ryuichi Koizumi; Akio Akagi; Yuichi Riku; Jun Sone; Mari Yoshida; Kenji Ihara; Yasushi Iwasaki
Brain pathology (Zurich, Switzerland), Aug. 2023
e13199, 10.1111/bpa.13199 - Nuclear Expression of TDP-43 Is Linked with Morphology and Ubiquitylation of Cytoplasmic Aggregates in Amyotrophic Lateral Sclerosis.
Hiroyuki Yabata; Yuichi Riku; Hiroaki Miyahara; Akio Akagi; Jun Sone; Makoto Urushitani; Mari Yoshida; Yasushi Iwasaki
International journal of molecular sciences, Jul. 2023
24(15), 10.3390/ijms241512176 - An autopsy case of copper deficiency myelopathy and selenium deficiency-associated central nervous system disorder after total parenteral nutrition.
Ryuichi Koizumi; Hideki Kato; Akio Akagi; Yuichi Riku; Jun Sone; Hiroaki Miyahara; Takuya Oguri; Hiroyuki Yuasa; Fumiaki Tanaka; Mari Yoshida; Yasushi Iwasaki
Journal of the neurological sciences, May 2023
448, 120636-120636, 10.1016/j.jns.2023.120636 - Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Chao Qi; Masato Hasegawa; Masaki Takao; Motoko Sakai; Mayasuki Sasaki; Masashi Mizutani; Akio Akagi; Yasushi Iwasaki; Hiroaki Miyahara; Mari Yoshida; Sjors H W Scheres; Michel Goedert
Acta neuropathologica communications, May 2023
11(1), 74-74, 10.1186/s40478-023-01565-2 - NOTCH2NLC GGC repeat expansion causes retinal pathology with intranuclear inclusions throughout the retina and causes visual impairment.
Jun Sone; Shinji Ueno; Akio Akagi; Hiroaki Miyahara; Chisato Tamai; Yuichi Riku; Hiroyuki Yabata; Ryuichi Koizumi; Tomohiro Hattori; Hiroshi Hirose; Yoshito Koyanagi; Rei Kobayashi; Hisashi Okada; Yoshiyuki Kishimoto; Yoshio Hashizume; Gen Sobue; Mari Yoshida; Yasushi Iwasaki
Acta neuropathologica communications, May 2023
11(1), 71-71, 10.1186/s40478-023-01564-3 - Epigenetic upregulation of Schlafen11 renders WNT- and SHH- activated medulloblastomas sensitive to cisplatin.
Satoshi Nakata; Junko Murai; Masayasu Okada; Haruhiko Takahashi; Tyler H Findlay; Kristen Malebranche; Akhila Parthasarathy; Satoshi Miyashita; Ramil Gabdulkhaev; Ilan Benkimoun; Sabine Druillennec; Sara Chabi; Eleanor Hawkins; Hiroaki Miyahara; Kensuke Tateishi; Shinji Yamashita; Shiori Yamada; Taiki Saito; Jotaro On; Jun Watanabe; Yoshihiro Tsukamoto; Junichi Yoshimura; Makoto Oishi; Toshimichi Nakano; Masaru Imamura; Chihaya Imai; Tetsuya Yamamoto; Hideo Takeshima; Atsuo T Sasaki; Fausto J Rodriguez; Sumihito Nobusawa; Pascale Varlet; Celio Pouponnot; Satoru Osuka; Yves Pommier; Akiyoshi Kakita; Yukihiko Fujii; Eric H Raabe; Charles G Eberhart; Manabu Natsumeda
Neuro-oncology, Oct. 2022
25(5), 899-912, 10.1093/neuonc/noac243 - Clinicopathological features of progressive supranuclear palsy with asymmetrical atrophy of the superior cerebellar peduncle.
Ryuichi Koizumi; Akio Akagi; Yuichi Riku; Jun Sone; Hiroaki Miyahara; Fumiaki Tanaka; Mari Yoshida; Yasushi Iwasaki
Neuropathology : official journal of the Japanese Society of Neuropathology, Oct. 2022
10.1111/neup.12868 - Clinical diagnosis sensitivity of neuropathologically established multiple system atrophy in Japan.
Takashi Ando; Yuichi Riku; Akio Akagi; Hiroaki Miyahara; Jun Sone; Masahisa Katsuno; Mari Yoshida; Yasushi Iwasaki
Journal of neurology, Sep. 2022
269(9), 5162-5164, 10.1007/s00415-022-11122-x - Macroscopic diagnostic clue for parkinsonism.
Mari Yoshida; Akio Akagi; Hiroaki Miyahara; Yuichi Riku; Takashi Ando; Toshimasa Ikeda; Hiroyuki Yabata; Hideyuki Moriyoshi; Ryuichi Koizumi; Yasushi Iwasaki
Neuropathology : official journal of the Japanese Society of Neuropathology, Aug. 2022
42(5), 394-419, 10.1111/neup.12853 - Neurolymphomatosis in follicular lymphoma: an autopsy case report.
Takashi Ando; Sonoko Kamoshita; Yuichi Riku; Ai Ito; Yukiyasu Ozawa; Koichi Miyamura; Masahiko Fujino; Masafumi Ito; Yoji Goto; Kazuo Mano; Akio Akagi; Hiroaki Miyahara; Masahisa Katsuno; Mari Yoshida; Yasushi Iwasaki
Neuropathology : official journal of the Japanese Society of Neuropathology, Aug. 2022
42(4), 295-301, 10.1111/neup.12807 - 脳腫瘍研究のcutting edge-先端画像、実験/分子病理、デジタル病理- 髄芽腫におけるGLI3 single cell RNAシーケンス解析 細胞レベルから見えて来たこと
棗田 学; 宮下 聡; 宮原 弘明; 高橋 晴彦; 塚本 佳広; 大石 誠; 吉村 淳一; 柿田 明美; 藤井 幸彦
Brain Tumor Pathology, May 2022
39(Suppl.), 072-072 - 抗ウイルス治療を受けた亜急性硬化性全脳炎症例の剖検脳におけるタウオパチーの検討(Secondary tauopathy following SSPE in autopsy cases treated with or without antiviral therapies)
宮原 弘明; 赤木 明生; 陸 雄一; 曽根 淳; 大塚 康史; 酒井 素子; 久留 聡; 長谷川 成人; 吉田 眞理; 柿田 明美; 岩崎 靖
脳と発達, May 2022
54(Suppl.), S214-S214 - Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive antiviral therapies.
Hiroaki Miyahara; Akio Akagi; Yuichi Riku; Jun Sone; Yasushi Otsuka; Motoko Sakai; Satoshi Kuru; Masato Hasegawa; Mari Yoshida; Akiyoshi Kakita; Yasushi Iwasaki
Brain pathology (Zurich, Switzerland), Apr. 2022
32(6), e13069, 10.1111/bpa.13069 - Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration.
Yuichi Riku; Yasushi Iwasaki; Shinsuke Ishigaki; Akio Akagi; Masato Hasegawa; Kenya Nishioka; Yuanzhe Li; Miho Riku; Takeshi Ikeuchi; Yusuke Fujioka; Hiroaki Miyahara; Jun Sone; Nobutaka Hattori; Mari Yoshida; Masahisa Katsuno; Gen Sobue
Brain : a journal of neurology, Mar. 2022, Reviewed
145(8), 2769-2784, 10.1093/brain/awac091 - Pathological observations of a long spinal cord lesion in a patient with multiple sclerosis.
Hiroyuki Yabata; Yufuko Saito; Takaaki Fukuoka; Akio Akagi; Yuichi Riku; Jun Sone; Hiroaki Miyahara; Manabu Doyu; Mari Yoshida; Yasushi Iwasaki
Neuropathology : official journal of the Japanese Society of Neuropathology, Feb. 2022
42(3), 212-217, 10.1111/neup.12800 - System degeneration in an MM1-type sporadic Creutzfeldt-Jakob disease case with an unusually prolonged akinetic mutism state.
Yasushi Iwasaki; Keiko Mori; Masumi Ito; Yoshinari Kawai; Akio Akagi; Yuichi Riku; Hiroaki Miyahara; Atsushi Kobayashi; Tetsuyuki Kitamoto; Mari Yoshida
Prion, Dec. 2021
15(1), 12-20, 10.1080/19336896.2020.1868931 - ロイシルtRNA合成酵素欠損ゼブラフィッシュを用いた乳児肝不全症候群の病態解明
井上 真紀; 宮原 弘明; 白石 裕士; 清水 誠之; 前田 美和子; 梅田 涼平; 石谷 太; 花田 礼子; 花田 俊勝; 井原 健二
日本先天代謝異常学会雑誌, Sep. 2021
37, 125-125 - ロイシルtRNA合成酵素欠損ゼブラフィッシュを用いた乳児肝不全症候群の病態解明
井上 真紀; 宮原 弘明; 白石 裕士; 清水 誠之; 前田 美和子; 梅田 涼平; 石谷 太; 花田 礼子; 花田 俊勝; 井原 健二
日本先天代謝異常学会雑誌, Sep. 2021
37, 125-125 - Metabolome Characteristics of Liver Autophagy Deficiency under Starvation Conditions in Infancy
Kazuhito Sekiguchi; Hiroaki Miyahara; Masanori Inoue; Kyoko Kiyota; Kumiko Sakai; Toshikatsu Hanada; Kenji Ihara
Nutrients, Aug. 2021
13(9), 3026-3026, 10.3390/nu13093026 - Cerebral pathological findings in long-lived patient with Werner syndrome and dementia.
Masafumi Kuzuya; Rong Q Shi; Madoka Yanagawa; Kazuhisa Watanabe; Satoshi Samizo; Ryota Ando; Hiroaki Miyahara; Yasushi Iwasaki; Mari Yoshida
Geriatrics & gerontology international, Aug. 2021
21(8), 743-745, 10.1111/ggi.14206 - The hot cross bun sign in corticobasal degeneration
Takashi Ando; Fuji Yokoi; Yuichi Riku; Akio Akagi; Hiroaki Miyahara; Masato Hasegawa; Masahisa Katsuno; Mari Yoshida; Yasushi Iwasaki
Neuropathology, Jul. 2021
41(5), 376-380, 10.1111/neup.12745 - Multiple system atrophy variant with severe hippocampal pathology.
Takashi Ando; Yuichi Riku; Akio Akagi; Hiroaki Miyahara; Mitsuaki Hirano; Toshimasa Ikeda; Hiroyuki Yabata; Ryuichi Koizumi; Chisato Oba; Saori Morozumi; Keizo Yasui; Atsuko Goto; Taiji Katayama; Satoko Sakakibara; Ikuko Aiba; Motoko Sakai; Masaaki Konagaya; Keiko Mori; Yasuhiro Ito; Hiroyuki Yuasa; Masayo Nomura; Kristine Joyce L Porto; Jun Mitsui; Shoji Tsuji; Maya Mimuro; Yoshio Hashizume; Masahisa Katsuno; Yasushi Iwasaki; Mari Yoshida
Brain pathology (Zurich, Switzerland), Jul. 2021
32(1), e13002, 10.1111/bpa.13002 - 臨床で進行性核上性麻痺とParkinson病の合併が疑われ、病理学的に確認された87歳女性例
古泉 龍一; 守吉 秀行; 矢端 博行; 安藤 孝志; 赤木 明生; 陸 雄一; 宮原 弘明; 田中 章景; 吉田 眞理; 岩崎 靖
パーキンソン病・運動障害疾患コングレスプログラム・抄録集, Jul. 2021
15回, 98-98 - Correction to: A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features.
Makoto Sainouchi; Yuya Hatano; Mari Tada; Tomohiko Ishihara; Shoichiro Ando; Taisuke Kato; Jun Tokunaga; Gaku Ito; Hiroaki Miyahara; Yasuko Toyoshima; Akio Yokoseki; Tetsutaro Ozawa; Kohei Akazawa; Osamu Onodera; Akiyoshi Kakita
Acta neuropathologica communications, Jun. 2021
9(1), 115-115, 10.1186/s40478-021-01217-3 - A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features.
Makoto Sainouchi; Yuya Hatano; Mari Tada; Tomohiko Ishihara; Shoichiro Ando; Taisuke Kato; Jun Tokunaga; Gaku Ito; Hiroaki Miyahara; Yasuko Toyoshima; Akio Yokoseki; Tetsutaro Ozawa; Kohei Akazawa; Osamu Onodera; Akiyoshi Kakita
Acta neuropathologica communications, Jun. 2021
9(1), 106-106, 10.1186/s40478-021-01202-w - 小児脳腫瘍の新展開 髄芽腫におけるGLI3発現および役割の解明 完結編
棗田 学; 宮原 弘明; 吉村 淳一; 塚本 佳広; 大石 誠; エバーハート・チャールズ; 柿田 明美; 藤井 幸彦
Brain Tumor Pathology, May 2021
38(Suppl.), 058-058 - Leucyl-tRNA synthetase deficiency systemically induces excessive autophagy in zebrafish.
Masanori Inoue; Hiroaki Miyahara; Hiroshi Shiraishi; Nobuyuki Shimizu; Mika Tsumori; Kyoko Kiyota; Miwako Maeda; Ryohei Umeda; Tohru Ishitani; Reiko Hanada; Kenji Ihara; Toshikatsu Hanada
Scientific reports, Apr. 2021
11(1), 8392-8392, 10.1038/s41598-021-87879-4 - Translation of GGC repeat expansions into a toxic polyglycine protein in NIID defines a novel class of human genetic disorders: the polyG diseases.
Manon Boivin; Jianwen Deng; Véronique Pfister; Erwan Grandgirard; Mustapha Oulad-Abdelghani; Bastien Morlet; Frank Ruffenach; Luc Negroni; Pascale Koebel; Hugues Jacob; Fabrice Riet; Anke A Dijkstra; Kathryn McFadden; Wiley A Clayton; Daojun Hong; Hiroaki Miyahara; Yasushi Iwasaki; Jun Sone; Zhaoxia Wang; Nicolas Charlet-Berguerand
Neuron, Apr. 2021
109(11), 1825-1835, 10.1016/j.neuron.2021.03.038 - Topoisomerase IIβ immunoreactivity (IR) co-localizes with neuronal marker-IR but not glial fibrillary acidic protein-IR in GLI3-positive medulloblastomas: an immunohistochemical analysis of 124 medulloblastomas from the Japan Children's Cancer Group.
Hiroaki Miyahara; Manabu Natsumeda; Yonehiro Kanemura; Kai Yamasaki; Yuichi Riku; Akio Akagi; Wataru Oohashi; Tomoko Shofuda; Ema Yoshioka; Yuya Sato; Takashi Taga; Yuki Naruke; Ryo Ando; Daiichiro Hasegawa; Makiko Yoshida; Tsukasa Sakaida; Naoki Okada; Hiroyoshi Watanabe; Michio Ozeki; Yoshiki Arakawa; Junichi Yoshimura; Yukihiko Fujii; Souichi Suenobu; Kenji Ihara; Junichi Hara; Akiyoshi Kakita; Mari Yoshida; Yasushi Iwasaki
Brain tumor pathology, Apr. 2021
38(2), 109-121, 10.1007/s10014-021-00396-0 - Genetic Variations and Neuropathologic Features of Patients With PRKN Mutations.
Naohiko Seike; Akio Yokoseki; Ryoko Takeuchi; Kento Saito; Hiroaki Miyahara; Akinori Miyashita; Tetsuhiko Ikeda; Izumi Aida; Takashi Nakajima; Masato Kanazawa; Masatoshi Wakabayashi; Yasuko Toyoshima; Hitoshi Takahashi; Riki Matsumoto; Tatsushi Toda; Osamu Onodera; Atsushi Ishikawa; Takeshi Ikeuchi; Akiyoshi Kakita
Movement disorders : official journal of the Movement Disorder Society, Feb. 2021
36(7), 1634-1643, 10.1002/mds.28521 - Clinicopathological findings of a mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes/Leigh syndrome overlap patient with a novel m.3482A>G mutation in MT-ND1.
Yuichi Hayashi; Yasushi Iwasaki; Nobuaki Yoshikura; Megumi Yamada; Akio Kimura; Takashi Inuzuka; Hiroaki Miyahara; Yuichi Goto; Ichizo Nishino; Mari Yoshida; Takayoshi Shimohata
Neuropathology : official journal of the Japanese Society of Neuropathology, Feb. 2021
41(1), 84-90, 10.1111/neup.12709 - GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma.
Manabu Natsumeda; Hiroaki Miyahara; Junichi Yoshimura; Satoshi Nakata; Takanori Nozawa; Junko Ito; Yu Kanemaru; Jun Watanabe; Yoshihiro Tsukamoto; Masayasu Okada; Makoto Oishi; Junko Hirato; Takafumi Wataya; Sama Ahsan; Kensuke Tateishi; Tetsuya Yamamoto; Fausto J Rodriguez; Hitoshi Takahashi; Volker Hovestadt; Mario L Suva; Michael D Taylor; Charles G Eberhart; Yukihiko Fujii; Akiyoshi Kakita
Journal of neuropathology and experimental neurology, Jan. 2021
80(2), 129-136, 10.1093/jnen/nlaa141 - 構語障害と嚥下障害で発症し、経過中に大動脈解離を合併した全経過2年半の死亡時88歳女性
一安 泰佑; 邦武 克彦; 稲垣 良輔; 古川 宗磨; 守吉 秀行; 鈴木 淳一郎; 西田 卓; 伊藤 泰広; 北川 諭; 宮原 弘明; 赤木 明生; 三室 マヤ; 岩崎 靖; 吉田 眞理
トヨタ医報, Nov. 2020
30, 212-214 - Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure.
Masayoshi Nakano; Yuichi Riku; Kenya Nishioka; Masato Hasegawa; Yukihiko Washimi; Yutaka Arahata; Akinori Takeda; Kentaro Horibe; Akiko Yamaoka; Keisuke Suzuki; Masashi Tsujimoto; Yuanzhe Li; Hiroyo Yoshino; Nobutaka Hattori; Akio Akagi; Hiroaki Miyahara; Yasushi Iwasaki; Mari Yoshida
Acta neuropathologica communications, Aug. 2020
8(1), 148-148, 10.1186/s40478-020-01025-1 - Topoisomerase IIβは髄芽腫細胞の神経分化を誘導する
宮原 弘明; 棗田 学; 吉村 淳一; 藤井 幸彦; 柿田 明美; 岩崎 靖; 吉田 眞理
Brain Tumor Pathology, Aug. 2020
37(Suppl.), 104-104 - Identification of intracerebral hemorrhage in the early-phase of MM1+2C-type sporadic Creutzfeldt-Jakob disease: A case report.
Akio Akagi; Yasushi Iwasaki; Akihiro Yamamoto; Hiroshi Matsuura; Toshimasa Ikeda; Maya Mimuro; Yuichi Riku; Hiroaki Miyahara; Tetsuyuki Kitamoto; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Aug. 2020, Reviewed, No invitation
40(4), 399-406, 10.1111/neup.12658 - The autophagy reaction in the human umbilical cord: a potential marker for estimating fetal nutrition and neonatal growth.
Kazuhito Sekiguchi; Hiroaki Miyahara; Masanori Inoue; Tomoki Maeda; Kenji Ihara
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, Mar. 2020, Reviewed, No invitation
35(4), 1-5, 10.1080/14767058.2020.1730320 - A case of M232R genetic Creutzfeldt-Jakob disease with Lewy bodies.
Akio Akagi; Yasushi Iwasaki; Rina Hashimoto; Ikuko Aiba; Akira Inukai; Maya Mimuro; Yuichi Riku; Hiroaki Miyahara; Tetsuyuki Kitamoto; Mari Yoshida
Journal of the neurological sciences, Feb. 2020, Reviewed, No invitation
409, 116605-116605, 10.1016/j.jns.2019.116605 - Correlating diffusion-weighted MRI intensity with type 2 pathology in mixed MM-type sporadic Creutzfeldt-Jakob disease.
Toshimasa Ikeda; Yasushi Iwasaki; Keita Sakurai; Akio Akagi; Yuichi Riku; Maya Mimuro; Hiroaki Miyahara; Tetsuyuki Kitamoto; Noriyuki Matsukawa; Mari Yoshida
Journal of the neurological sciences, Jan. 2020, Reviewed, No invitation
408, 116515-116515, 10.1016/j.jns.2019.116515 - Autopsy case of MV2K-type sporadic Creutzfeldt-Jakob disease with spongiform changes of the cerebral cortex.
Yasushi Iwasaki; Keita Hiraga; Shota Ito; Tetsuo Ando; Akio Akagi; Yuichi Riku; Maya Mimuro; Hiroaki Miyahara; Atsushi Kobayashi; Tetsuyuki Kitamoto; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Dec. 2019, Reviewed, No invitation
39(6), 452-460, 10.1111/neup.12595 - Autopsied case with MERRF/MELAS overlap syndrome accompanied by stroke-like episodes localized to the precentral gyrus.
Hiroaki Miyahara; Shinjiro Matsumoto; Kenji Mokuno; Rika Dei; Akio Akagi; Maya Mimuro; Yasushi Iwasaki; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Jun. 2019, Reviewed, No invitation
39(3), 212-217, 10.1111/neup.12551 - Autopsied case of sporadic Creutzfeldt-Jakob disease classified as MM1+2C-type.
Yasushi Iwasaki; Hiroko Kato; Tetsuo Ando; Akio Akagi; Maya Mimuro; Hiroaki Miyahara; Atsushi Kobayashi; Tetsuyuki Kitamoto; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Jun. 2019, Reviewed, No invitation
39(3), 240-247, 10.1111/neup.12557 - Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma.
Manabu Natsumeda; Yang Liu; Satoshi Nakata; Hiroaki Miyahara; Allison Hanaford; Sama Ahsan; Duncan Stearns; Nicolas Skuli; Ulf D Kahlert; Eric H Raabe; Fausto J Rodriguez; Charles G Eberhart
Neuropathology : official journal of the Japanese Society of Neuropathology, Apr. 2019, Reviewed, No invitation
39(2), 71-77, 10.1111/neup.12534 - An autopsied case of MM1-type sporadic Creutzfeldt-Jakob disease with pathology of Wernicke encephalopathy.
Yasushi Iwasaki; Rina Hashimoto; Yufuko Saito; Ikuko Aiba; Akira Inukai; Akio Akagi; Maya Mimuro; Hiroaki Miyahara; Tetsuyuki Kitamoto; Mari Yoshida
Prion, Jan. 2019, Reviewed, No invitation
13(1), 13-20, 10.1080/19336896.2018.1545525 - Autopsy case of V180I genetic Creutzfeldt-Jakob disease presenting with early disease pathology.
Yasushi Iwasaki; Hiroko Kato; Tetsuo Ando; Akio Akagi; Maya Mimuro; Hiroaki Miyahara; Tetsuyuki Kitamoto; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Dec. 2018, Reviewed, No invitation
38(6), 638-645, 10.1111/neup.12516 - Autopsied centenarian case of Alzheimer's disease combined with hippocampal sclerosis, TDP-43, and α-synuclein pathologies.
Yasushi Iwasaki; Akira Deguchi; Keiko Mori; Masumi Ito; Yoshinari Kawai; Akio Akagi; Maya Mimuro; Hiroaki Miyahara; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Dec. 2018, Reviewed, No invitation
38(6), 653-659, 10.1111/neup.12521 - Auto-immune disorders in a child with PIK3CD variant and 22q13 deletion.
Kyoko Kiyota; Koh-Ichiro Yoshiura; Ryoko Houbara; Hiroaki Miyahara; Seigo Korematsu; Kenji Ihara
European journal of medical genetics, Oct. 2018, Reviewed, No invitation
61(10), 631-633, 10.1016/j.ejmg.2018.04.008 - Autopsied case of non-plaque-type dura mater graft-associated Creutzfeldt-Jakob disease presenting with extensive amyloid-β deposition.
Yasushi Iwasaki; Kazuhiro Imamura; Katsushige Iwai; Yasushi Kobayashi; Akio Akagi; Maya Mimuro; Hiroaki Miyahara; Tetsuyuki Kitamoto; Mari Yoshida
Neuropathology : official journal of the Japanese Society of Neuropathology, Oct. 2018, Reviewed, No invitation
38(5), 549-556, 10.1111/neup.12503 - 筋力低下を呈し筋病理所見で還元小体を認め、FHL1遺伝子変異を同定した小児期発症の4例における臨床的特徴
草開 祥平; 井上 道雄; 石山 昭彦; 大矢 寧; 宮原 弘明; 竹下 絵里; 本橋 裕子; 齋藤 貴志; 小牧 宏文; 中川 栄二; 須貝 研司; 佐々木 征行; 西野 一三
脳と発達, May 2018, Reviewed, No invitation
50(Suppl.), S316-S316 - Unique cell tropism of HHV-6B in an infantile autopsy case of primary HHV-6B encephalitis.
Hiroaki Miyahara; Kouki Miyakawa; Haruto Nishida; Shinji Yano; Tomoko Sonoda; So-Ichi Suenobu; Tatsuro Izumi; Tsutomu Daa; Kenji Ihara
Neuropathology : official journal of the Japanese Society of Neuropathology, Mar. 2018, Reviewed, No invitation
10.1111/neup.12462 - Correction of a large aortic lesion in a girl with PHACE syndrome : sequential evaluation with radiological images for surgical intervention
後藤 洋徳; 中嶋 美咲; 宮原 弘明; 末延 聡一; 宗内 淳; 落合 由恵; 笹栗 毅和; 井原 健二
小児科臨床, Aug. 2017, Not reviewed, No invitation
70(8), 1289-1293 - The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.
Hiroaki Miyahara; Sridevi Yadavilli; Manabu Natsumeda; Jeffrey A Rubens; Louis Rodgers; Madhuri Kambhampati; Isabella C Taylor; Harpreet Kaur; Laura Asnaghi; Charles G Eberhart; Katherine E Warren; Javad Nazarian; Eric H Raabe
Cancer letters, Aug. 2017, Reviewed, No invitation
400, 110-116, 10.1016/j.canlet.2017.04.019 - IVIG-triggered tubulointerstitial nephritis in X-linked agammaglobulinemia.
Masahiro Takeguchi; Seigo Korematsu; Hiroaki Miyahara; Shuji Kuga; Tatsuro Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Aug. 2017, Reviewed, No invitation
59(8), 945-946, 10.1111/ped.13329 - Central hypoadrenocorticism associated with Rathke's cleft cyst.
Fumika Kawano; Tomoyo Itonaga; Masanori Inoue; Miwako Maeda; Hiroaki Miyahara; Kenji Ihara
Neuro endocrinology letters, Jul. 2017, Reviewed, No invitation
38(3), 141-144 - Increased levels of anti-phosphatidylcholine and anti-phosphatidylethanolamine antibodies in pediatric patients with cerebral infarction.
Seigo Korematsu; Hiroshi Yamada; Hiroaki Miyahara; Kenji Ihara
Brain & development, Jun. 2017, Reviewed, No invitation
39(6), 542-546, 10.1016/j.braindev.2017.01.010 - Heparan sulfate storage in the cardiac conduction system triggers atrioventricular block.
Rie Kato; Hiroaki Miyahara; Tatsuya Kawano; Atsuko Matsuzuka; Kimiko Noda; Tatsuro Izumi
Brain & development, May 2017, Reviewed, No invitation
39(5), 418-421, 10.1016/j.braindev.2016.12.008 - A severe pulmonary complication in a patient with COL4A1-related disorder: A case report.
Yoshiichi Abe; Atsuko Matsuduka; Kazuo Okanari; Hiroaki Miyahara; Mitsuhiro Kato; Satoko Miyatake; Hirotomo Saitsu; Naomichi Matsumoto; Maeda Tomoki; Kenji Ihara
European journal of medical genetics, Mar. 2017, Reviewed, No invitation
60(3), 169-171, 10.1016/j.ejmg.2016.12.008 - Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres.
Manabu Natsumeda; Kosuke Maitani; Yang Liu; Hiroaki Miyahara; Harpreet Kaur; Qian Chu; Hongyan Zhang; Ulf D Kahlert; Charles G Eberhart
Brain pathology (Zurich, Switzerland), Nov. 2016, Reviewed, No invitation
26(6), 713-723, 10.1111/bpa.12343 - [Gli3: a favorable prognostic factor for patients with medulloblastoma].
Junichi Yoshimura; Hiroaki Miyahara; Manabu Natsumeda; Akiyoshi Kakita; Yukihiko Fujii
Nihon rinsho. Japanese journal of clinical medicine, Sep. 2016, Reviewed, No invitation
74 Suppl 7, 292-297 - 起立性調節障害との鑑別を要した下垂体機能低下症の1例
河野 史佳; 井上 真紀; 宮原 弘明; 前田 美和子; 井原 健二
日本小児科学会雑誌, Oct. 2015
119(10), 1534-1534 - Overexpression of p53 but not Rb in the cytoplasm of neurons and small vessels in an autopsy of a patient with Cockayne syndrome.
Hiroaki Miyahara; Tomoyo Itonaga; Tomoki Maeda; Tatsuro Izumi; Kenji Ihara
Neuropathology : official journal of the Japanese Society of Neuropathology, Jun. 2015, Reviewed, No invitation
35(3), 266-72, 10.1111/neup.12183 - 高張性脱水によりWallenberg症候群を呈した12ヵ月女児例
山田 博; 後藤 洋徳; 井上 真紀; 宮原 弘明; 黒川 麻里; 古賀 寛史; 泉 達郎
日本小児科学会雑誌, Mar. 2015
119(3), 621-622 - Elevated serum anti-phosphatidylcholine IgG antibodies in patients with influenza vaccination-associated optic neuritis.
Seigo Korematsu; Hiroaki Miyahara; Akiyoshi Kakita; Tatsuro Izumi
Vaccine, Nov. 2014, Reviewed, No invitation
32(48), 6345-8, 10.1016/j.vaccine.2014.09.053 - Progressive dysautonomia in two patients with xeroderma pigmentosum group A.
Osamu Kobayashi; Hiroaki Miyahara; Naho Abe; Chika Goto; Kazuo Okanari; Kensuke Akiyoshi; Seigo Korematsu; Tatsuro Izumi
Pediatric neurology, Jun. 2014, Reviewed, No invitation
50(6), 619-21, 10.1016/j.pediatrneurol.2014.01.026 - Hemimegalencephaly in a patient with coexisting trisomy 21 and hypomelanosis of Ito.
Kazuo Okanari; Hiroaki Miyahara; Masayuki Itoh; Akio Takahashi; Koichi Aizaki; Eiji Nakagawa; Taisuke Otsuki; Tatsuro Izumi
Journal of child neurology, Mar. 2014, Reviewed, No invitation
29(3), 415-20, 10.1177/0883073812469297 - Neuronal differentiation associated with Gli3 expression predicts favorable outcome for patients with medulloblastoma.
Hiroaki Miyahara; Manabu Natsumeda; Junichi Yoshimura; Ryosuke Ogura; Kenichi Okazaki; Yasuko Toyoshima; Yukihiko Fujii; Hitoshi Takahashi; Akiyoshi Kakita
Neuropathology : official journal of the Japanese Society of Neuropathology, Feb. 2014, Reviewed, No invitation
34(1), 1-10, 10.1111/neup.12052 - P-078 川崎病冠動脈瘤形成の基礎病態 : 顆粒球MMP9と血小板TIMP1の細胞成分分画の検討(小児膠原病・自己炎症疾患,口演11,第26回日本アレルギー学会春季臨床大会)
是松 聖悟; 宮原 弘明; 泉 達郎
アレルギー, 2014
63(3), 562-562, 10.15036/arerugi.63.562_2 - Suppressed expression of autophagosomal protein LC3 in cortical tubers of tuberous sclerosis complex.
Hiroaki Miyahara; Manabu Natsumeda; Atsushi Shiga; Hiroshi Aoki; Yasuko Toyoshima; Yingjun Zheng; Ryoko Takeuchi; Hiroatsu Murakami; Hiroshi Masuda; Shigeki Kameyama; Tatsuro Izumi; Yukihiko Fujii; Hitoshi Takahashi; Akiyoshi Kakita
Brain pathology (Zurich, Switzerland), May 2013, Reviewed, No invitation
23(3), 254-62, 10.1111/j.1750-3639.2012.00634.x - P-160 卵アレルギー患児における血清TARC値の経年的推移と耐性獲得との相関についての検討(食物アレルギーの発症メカニズム1,ポスター発表,一般演題)
宮原 弘明; 是松 聖悟; 泉 達郎
アレルギー, 2013
62(3), 426-426, 10.15036/arerugi.62.426_4 - Cell distribution differences of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in patients with Kawasaki disease.
Seigo Korematsu; Yoko Ohta; Naotaka Tamai; Masahiro Takeguchi; Chika Goto; Hiroaki Miyahara; Tatsuya Kawano; Tatsuro Izumi
The Pediatric infectious disease journal, Sep. 2012, Reviewed, No invitation
31(9), 973-4, 10.1097/INF.0b013e31825ba6b3 - 公的補助による任意予防接種と医療費控除の小児医療、地域社会への影響
是松聖悟; 秋吉健介; 高野智幸; 関口和人; 岡成和夫; 武口真広; 岡本知子; 園田幸司; 加藤里絵; 松塚敦子; 半田陽祐; 島田祐美; 宮原弘明; 前田美和子; 山田博; 前田知己; 末延聡一; 拜郷敦彦; 泉 達郎
日本小児科学会雑誌, 2012, Reviewed, No invitation
116(9), 1380-1386 - Induction of autophagy in temozolomide treated malignant gliomas.
Manabu Natsumeda; Hiroshi Aoki; Hiroaki Miyahara; Naoki Yajima; Takeo Uzuka; Yasuko Toyoshima; Akiyoshi Kakita; Hitoshi Takahashi; Yukihiko Fujii
Neuropathology : official journal of the Japanese Society of Neuropathology, Oct. 2011, Reviewed, No invitation
31(5), 486-93, 10.1111/j.1440-1789.2010.01197.x - Hypertrophy of hippocampal end folium neurons in patients with mesial temporal lobe epilepsy.
Masae Ryufuku; Yasuko Toyoshima; Hiroki Kitaura; Yingjun Zheng; Yong-Juan Fu; Hiroaki Miyahara; Hiroatsu Murakami; Hiroshi Masuda; Shigeki Kameyama; Hitoshi Takahashi; Akiyoshi Kakita
Neuropathology : official journal of the Japanese Society of Neuropathology, Oct. 2011, Reviewed, No invitation
31(5), 476-85, 10.1111/j.1440-1789.2010.01191.x - Detection of platelet-binding anti-measles and anti-rubella virus IgG antibodies in infants with vaccine-induced thrombocytopenic purpura.
Naho Okazaki; Masahiro Takeguchi; Kohji Sonoda; Yohsuke Handa; Tatsuo Kakiuchi; Hiroaki Miyahara; Kensuke Akiyoshi; Seigo Korematsu; Soichi Suenobu; Tatsuro Izumi
Vaccine, Jul. 2011, Reviewed, No invitation
29(31), 4878-80, 10.1016/j.vaccine.2011.04.036 - Anaplastic astrocytoma with angiocentric ependymal differentiation.
Hiroaki Miyahara; Yasuko Toyoshima; Manabu Natsumeda; Takeo Uzuka; Hiroshi Aoki; Yoko Nakayama; Kouichiou Okamoto; Yukihiko Fujii; Akiyoshi Kakita; Hitoshi Takahashi
Neuropathology : official journal of the Japanese Society of Neuropathology, Jun. 2011, Reviewed, No invitation
31(3), 292-8, 10.1111/j.1440-1789.2010.01161.x - Elevated umbilical cord serum TARC/CCL17 levels predict the development of atopic dermatitis in infancy
H. Miyahara; N. Okazaki; T. Nagakura; S. Korematsu; T. Izumi
Clinical & Experimental Allergy, Feb. 2011, Reviewed, No invitation
41(2), 186-191, 10.1111/j.1365-2222.2010.03634.x - Balloon cells in the dentate gyrus in hippocampal sclerosis associated with non-herpetic acute limbic encephalitis.
Hiroaki Miyahara; Masae Ryufuku; Yong-Juan Fu; Hiroki Kitaura; Hiroatsu Murakami; Hiroshi Masuda; Shigeki Kameyama; Hitoshi Takahashi; Akiyoshi Kakita
Seizure, Jan. 2011, Reviewed, No invitation
20(1), 87-9, 10.1016/j.seizure.2010.09.013 - Intraventricular pleomorphic xanthoastrocytoma with anaplastic features.
Yong-Juan Fu; Hiroaki Miyahara; Takeo Uzuka; Manabu Natsumeda; Kouichirou Okamoto; Takanori Hirose; Yukihiko Fujii; Hitoshi Takahashi
Neuropathology : official journal of the Japanese Society of Neuropathology, Aug. 2010, Reviewed, No invitation
30(4), 443-8, 10.1111/j.1440-1789.2009.01080.x - 大脳皮質・白質を侵すdiffuse astrocytomaを背景に、angiocentric glioma様組織像を示した1生検例
宮原 弘明; 豊島 靖子; 宇塚 岳夫; 青木 洋; 中山 遙子; 柿田 明美; 高橋 均
Brain Tumor Pathology, May 2010
27(Suppl.), 126-126 - The indication and effectiveness of low-dose erythromycin therapy in pediatric patients with bronchial asthma.
Seigo Korematsu; Kyoko Yamamoto; Tomokazu Nagakura; Hiroaki Miyahara; Naho Okazaki; Kensuke Akiyoshi; Tomoki Maeda; So-ichi Suenobu; Tatsuro Izumi
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, May 2010, Reviewed, No invitation
21(3), 489-92, 10.1111/j.1399-3038.2009.00941.x - Ictal bradycardia in an infant following surgical treatment for hemimegalencephaly.
Hiroaki Miyahara; Kouji Sonoda; Naho Okazaki; Kazuhito Sekiguchi; Tatsuya Kawano; Kensuke Akiyoshi; Tomoki Maeda; Tatsuro Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Feb. 2010, Reviewed, No invitation
52(1), 156-7, 10.1111/j.1442-200X.2009.02982.x - O33-4 食物アレルギー児の除去食における微量元素欠乏の臨床病態の検討(O33 食物アレルギー・その他,口演,第60回日本アレルギー学会秋季学術大会)
岡崎 直歩; 宮原 弘明; 長倉 智和; 是松 聖悟
アレルギー, 2010
59(9), 1408-1408, 10.15036/arerugi.59.1408_3 - A relapse of systemic type juvenile idiopathic arthritis after a rubella vaccination in a patient during a long-term remission period.
Seigo Korematsu; Hiroaki Miyahara; Tatsuya Kawano; Hiroshi Yamada; Kensuke Akiyoshi; Keisuke Sato; Tomoki Maeda; So-ichi Suenobu; Tatsuro Izumi
Vaccine, Aug. 2009, Reviewed, No invitation
27(37), 5041-2, 10.1016/j.vaccine.2009.06.052 - 過疎地域医療、小児・周産期医療を担う医師確保対策調査
是松聖悟; 秋吉健介; 高野智幸; 拜郷敦彦; 末延聡一; 前田知己; 清田晃生; 川野達也; 宮原弘明; 半田陽祐; 岡成和夫; 岡﨑直歩; 前田美和子; 和泉啓; 加藤里絵; 武口真広; 奈須家栄; 吉松淳; 楢原久司; 泉 達郎
日本小児科学会雑誌, 2009, Reviewed, No invitation
113(10), 1587-1592 - Theophylline-associated seizures and their clinical characterizations.
Seigo Korematsu; Hiroaki Miyahara; Tomokazu Nagakura; Soichi Suenobu; Tatsuro Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Feb. 2008, Reviewed, No invitation
50(1), 95-8, 10.1111/j.1442-200X.2007.02524.x - Efficacy of fluticasone metered-dose inhaler and dry powder inhaler for pediatric asthma.
Hiroaki Miyahara; Seigo Korematsu; Tomokazu Nagakura; Tatsuro Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Feb. 2008, Reviewed, No invitation
50(1), 103-8, 10.1111/j.1442-200X.2007.02523.x - P187 アレルギー発症における胎内環境の影響 : 母体血,臍帯血TARCとアレルギー発症との相関(サイトカイン・ケモカイン,第20回日本アレルギー学会春季臨床大会)
宮原 弘明; 岡崎 直歩; 是松 聖悟; 泉 達郎
アレルギー, 2008
57(3), 427-427, 10.15036/arerugi.57.427_3 - Hemophagocytic lymphohistiocytosis in a human immunodeficiency virus-positive homosexual high school student.
Hiroaki Miyahara; Seigo Korematsu; Tomokazu Nagakura; Atsuko Iwata; Souichi Suenobu; Tatsuto Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Dec. 2007, Reviewed, No invitation
49(6), 997-9, 10.1111/j.1442-200X.2007.02466.x - The characterization of cerebrospinal fluid and serum cytokines in patients with Kawasaki disease.
Seigo Korematsu; Shin-ichi Uchiyama; Hiroaki Miyahara; Tomokazu Nagakura; Naho Okazaki; Tatsuya Kawano; Masanobu Kojo; Tatsuro Izumi
The Pediatric infectious disease journal, Aug. 2007, Reviewed, No invitation
26(8), 750-3, 10.1097/INF.0b013e3180f61708 - MS8-4 乳児期のアトピー性皮膚炎における特異IgEとパッチテストの比較(アトピー性皮膚炎の新知見, 第19回日本アレルギー学会春季臨床大会)
宮原 弘明; 是松 聖悟; 岡崎 直歩; 泉 達郎
アレルギー, 2007
56(3), 325-325, 10.15036/arerugi.56.325_3 - 265 小児難治性気管支喘息に対する少量エリスロマイシン療法と,その有効機序の検討(気管支喘息-治療6,一般演題(口演),第56回日本アレルギー学会秋季学術大会)
是松 聖悟; 宮原 弘明; 長倉 智和; 泉 達郎
アレルギー, 2006
55(8), 1189-1189, 10.15036/arerugi.55.1189_1 - Increase of cerebrospinal fluid soluble interleukin-2 receptor index in a patient with atopy and syringohydromyelia.
Seigo Korematsu; Hiroaki Miyahara; Maki Takaji; Shin-Ichi Uchiyama; Tomokazu Nagakura; Soichi Suenobu; Masanobu Kojo; Tatsuro Izumi
Pediatrics international : official journal of the Japan Pediatric Society, Aug. 2005, Reviewed, No invitation
47(4), 459-62 - 463 フルチカゾンのスペーサー併用定量噴霧吸入とドライパウダー吸入による呼吸機能改善度の差異(気管支喘息-治療(8), 第55回日本アレルギー学会秋季学術大会)
宮原 弘明; 是松 聖悟; 泉 達郎
アレルギー, 2005
54(8), 1122-1122, 10.15036/arerugi.54.1122_3
MISC
- 構語障害と嚥下障害で発症し,経過中に大動脈解離を合併した全経過2年半の死亡時88歳女性
一安泰佑; 邦武克彦; 稲垣良輔; 古川宗磨; 守吉秀行; 鈴木淳一郎; 西田卓; 伊藤泰広; 北川諭; 宮原弘明; 赤木明生; 三室マヤ; 岩崎靖; 吉田眞理
トヨタ医報, 2020
30 - MYC高発現髄芽腫に対してEZH2阻害剤を用いた新規治療戦略
棗田学; 棗田学; 中田聡; 宮原弘明; 宮原弘明; 吉村淳一; 大石誠; 藤井幸彦
小児の脳神経, 30 Apr. 2019, Not reviewed, No invitation
44(2), 139 - びまん性正中グリオーマの細胞株を用いた薬剤治療研究
宮原弘明; 宮原弘明; 棗田学; 棗田学; 藤井幸彦; 吉田眞理
小児の脳神経, 30 Apr. 2019, Not reviewed, No invitation
44(2), 140 - プリオン病100剖検例の網羅的検討
岩崎靖; 赤木明生; 三室マヤ; 宮原弘明; 吉田眞理
日本病理学会会誌, 15 Apr. 2019, Not reviewed, No invitation
108(1), 311 - H3K9 methyltransferase inhibitor BIX01294 inhibits tumorigenicity in diffuse intrinsic pontine glioma and glioblastoma
Miyahara Hiroaki; Natsumeda Manabu; Koldobsky Michael; Liu Yang; Kaur Harpreet; Asnaghi Laura; Yoshida Mari; Eberhart Charles G; Raabe Eric H
BRAIN PATHOLOGY, Feb. 2019, Reviewed, No invitation
29, 156 - Temozolomide and Notch inhibitor MRK-003 induce cell protective autophagy in malignant gliomas
Natsumeda Manabu; Aoki Hiroshi; Miyahara Hiroaki; Kakita Akiyoshi; Takahashi Hitoshi; Eberhart Charles G; Fujii Yukihiko
BRAIN PATHOLOGY, Feb. 2019, Reviewed, No invitation
29, 142 - Creutzfeldt‐Jakob病では発症4ヶ月よりαB‐Crystallin陽性神経細胞が出現する
赤木明生; 三室マヤ; 宮原弘明; 岩崎靖; 吉田眞理
日本神経学会学術大会プログラム・抄録集, 2019, Not reviewed, No invitation
60th, 443 - プリオン病100剖検例の網羅的検討
岩崎靖; 赤木明生; 三室マヤ; 宮原弘明; 吉田眞理
日本神経学会学術大会プログラム・抄録集, 2019, Not reviewed, No invitation
60th, 442 - 当施設におけるプリオン病100剖検例の検討
岩崎靖; 赤木明生; 三室マヤ; 宮原弘明; 吉田眞理
Neuroinfection, 10 Oct. 2018, Not reviewed, No invitation
23(2), 241 - 日本人剖検脳における加齢性変化の程度と拡がり
三室マヤ; 赤木明生; 宮原弘明; 岩崎靖; 吉田眞理
Dementia Japan, 15 Sep. 2018, Not reviewed, No invitation
32(3), 419 - MM1型・MM2型を合併したsCJDにおけるMRI拡散強調像と各病変分布の検討
池田知雅; 池田知雅; 岩崎靖; 櫻井圭太; 赤木明生; 三室マヤ; 宮原弘明; 松川則之; 吉田眞理
Dementia Japan, 15 Sep. 2018, Not reviewed, No invitation
32(3), 456-456 - 当施設におけるプリオン病100剖検例の検討
岩崎靖; 赤木明生; 三室マヤ; 宮原弘明; 吉田眞理
Dementia Japan, 15 Sep. 2018, Not reviewed, No invitation
32(3), 458 - 腎血管性高血圧症と反復する肺胞出血を契機に診断したCOL4A1遺伝子異常の1例
安部 義一; 松塚 敦子; 平野 直樹; 岡成 和夫; 宮原 弘明; 加藤 光広; 井原 健二
日本小児科学会雑誌, Aug. 2018, Not reviewed, No invitation
122(8), 1366-1366 - 川崎病に合併した環軸椎回旋位固定の臨床的特徴 自験例を含む国内13症例の検討
山口 智之; 宮原 弘明; 藤本 保; 是松 聖悟; 井原 健二
アルメイダ医報, Jun. 2018, Not reviewed, No invitation
43(1), 45-49 - Gli3 INDUCES NEURONAL DIFFERENTIATION IN WNT- AND SHH-ACTIVATED MEDULLOBLASTOMA
Manabu Natsumeda; Hiroaki Miyahara; Junichi Yoshimura; Takanori Nozawa; Yoshihiro Tsukamoto; Takafumi Wataya; Charles Eberhart; Hitoshi Takahashi; Akiyoshi Kakita; Yukihiko Fujii
NEURO-ONCOLOGY, Nov. 2017, Reviewed, No invitation
19, 183-183 - 分子病理と分子病態 Oncogenesis and Progression WNT群、SHH群におけるGli3高発現と神経細胞分化
棗田 学; 吉村 淳一; 宮原 弘明; 野澤 孝徳; 塚本 佳広; 綿谷 崇史; Eberhart Charles; 高橋 均; 柿田 明美; 藤井 幸彦
Brain Tumor Pathology, May 2017, Not reviewed, No invitation
34(Suppl.), 073-073 - C-myc高発現髄芽腫に対してEZH2 inhibitorを用いた新規治療戦略
棗田 学; 宮原 弘明; 吉村 淳一; 大石 誠; 藤井 幸彦; チャールズ・エバーハート
小児の脳神経, Apr. 2017, Not reviewed, No invitation
42(2), 120-120 - 【脳腫瘍学-基礎研究と臨床研究の進歩-】 脳腫瘍の予後因子 髄芽腫の予後因子Gli3
吉村 淳一; 宮原 弘明; 棗田 学; 柿田 明美; 藤井 幸彦
日本臨床, Sep. 2016, Not reviewed, No invitation
74(増刊7 脳腫瘍学), 292-297 - CELL CULTURE CONDITIONS AFFECT DIFFUSE INTRINSIC PONTINE GLIOMA EPIGENETICS AND RESPONSE TO THERAPEUTIC AGENTS
Sama Ahsan; Michael Haffner; Hiroaki Miyahara; Manabu Natsumeda; Yang Liu; Lauren Rocco; Charles Eberhart; Eric Raabe
NEURO-ONCOLOGY, Jun. 2016, Reviewed, No invitation
18, 64-64 - 髄芽腫のmolecular分類 MAGIC分類とGli3免疫染色の対比
吉村 淳一; 宮原 弘明; 綿谷 崇史; 清家 尚彦; 棗田 学; 柿田 明美; 藤井 幸彦
Brain Tumor Pathology, May 2016, Not reviewed, No invitation
33(Suppl.), 096-096 - 脳腫瘍病理学の新傾向 日常の病理組織診断への分子遺伝学の応用(パートII)(髄芽腫) Gli3は髄芽腫におけるニューロンおよびグリア分化に関連する(New Trends in Brain Tumor Pathology: Application of Molecular Genetics to Routine Histopathological Diagnosis(Part II)(Medulloblastoma) Gli3 is Associated with Neuronal and Glial Di
棗田 学; 宮原 弘明; 吉村 淳一; 西山 健一; 豊島 靖子; 柿田 明美; 高橋 均; 藤井 幸彦
Brain Tumor Pathology, May 2012, Not reviewed, No invitation
29(Suppl.), 116-116 - MS4-1 網膜中心静脈閉塞を来たした抗カルジオリピン抗体陰性の抗リン脂質抗体症候群の女児例(MS4 自己免疫疾患,ミニシンポジウム,第24回日本アレルギー学会春季臨床大会)
是松 聖悟; 後藤 洋徳; 後藤 千佳; 宮原 弘明; 泉 達郎
アレルギー, 2012, Not reviewed, No invitation
61(3), 468-468, 10.15036/arerugi.61.468_1 - 効果判定のための病理診断 Pseudoprogression症例におけるMGMT発現及びオートファジー誘導の検討
棗田 学; 青木 洋; 宮原 弘明; 宇塚 岳夫; 柿田 明美; 高橋 均; 藤井 幸彦
Brain Tumor Pathology, May 2011, Not reviewed, No invitation
28(Suppl.), 052-052 - 髄芽腫におけるGli3の発現 神経細胞への分化と良好な患者予後との関連
宮原 弘明; 棗田 学; 吉村 淳一; 豊島 靖子; 藤井 幸彦; 高橋 均; 柿田 明美
Brain Tumor Pathology, May 2011, Not reviewed, No invitation
28(Suppl.), 081-081 - 脳腫瘍における術中迅速免疫組織化学的診断の有用性
宇塚 岳夫; 棗田 学; 青木 洋; 宮原 弘明; 柿田 明美; 高橋 均; 藤井 幸彦
Brain Tumor Pathology, May 2010, Not reviewed, No invitation
27(Suppl.), 71-71 - 悪性神経膠腫症例におけるオートファジーモニタリングと治療抵抗性獲得の検討
棗田 学; 青木 洋; 宮原 弘明; 宇塚 岳夫; 豊島 靖子; 柿田 明美; 高橋 均; 藤井 幸彦
Brain Tumor Pathology, May 2010, Not reviewed, No invitation
27(Suppl.), 101-101 - 7 症候性光過敏性後頭葉てんかんと視床下部性GH分泌不全、自閉障害を呈した先天性サイトメガロウイルス感染症の1例(第2回日本てんかん学会九州地方会)
後藤 千佳; 石飛 佳宣; 宮原 弘明; 小杉 雄二郎; 秋吉 健介; 佐藤 圭右; 泉 達郎
てんかん研究, 31 Aug. 2007
25(2), 136-136
Research Themes
- Investigation of pleiotropic etiology of epilepsy by generating rapid and precise gene-edited mouse
Grant-in-Aid for Scientific Research (C)
Institute for Developmental Research Aichi Developmental Disability Center
01 Apr. 2024 - 31 Mar. 2027
林 深; 宮原 弘明, 林 深; 宮原 弘明, 日本学術振興会, Japan Society for the Promotion of Science - Mitochondria function analysis using autopsied brain samples of MELAS
Grant-in-Aid for Scientific Research (C)
Aichi Medical University
01 Apr. 2020 - 31 Mar. 2025
宮原 弘明; 吉田 眞理; 岩崎 靖; 井原 健二; 井上 真紀; 関口 和人, 宮原 弘明; 吉田 眞理; 岩崎 靖; 井原 健二; 井上 真紀; 関口 和人, 日本学術振興会, Japan Society for the Promotion of Science - Mechanisms of lesion formation in Parkinson's disease: an analysis using tissue clearing and 3D observation
Grant-in-Aid for Scientific Research (C)
Niigata University
01 Apr. 2019 - 31 Mar. 2022
清水 宏; 柿田 明美; 吉田 眞理; 宮原 弘明, Shimizu Hiroshi, 日本学術振興会, Japan Society for the Promotion of Science - The role of autophagy in starvation response immediately after birth
Grant-in-Aid for Scientific Research (C)
Oita University
01 Apr. 2017 - 31 Mar. 2020
関口 和人; 宮原 弘明; 花田 俊勝, Sekiguchi Kazuhito, 日本学術振興会, Japan Society for the Promotion of Science - Evaluation of mitophagy activity in patients with Leigh encephalopathy
Grant-in-Aid for Scientific Research (C)
01 Apr. 2015 - 31 Mar. 2019
宮原 弘明; 井原 健二, Miyahara Hiroaki, 日本学術振興会, Japan Society for the Promotion of Science - The therapeutic research using Autophagy in Tuberous sclerosis complex
Grant-in-Aid for Young Scientists (B)
Oita University
01 Apr. 2012 - 31 Mar. 2015
宮原 弘明, MIYAHARA HIROAKI, 日本学術振興会, Japan Society for the Promotion of Science
