PCOS mouse model

Polycystic Ovarian syndrome

Reproductive medicine, Reproduction

Serum miRNA as a predictive biomarker for ovarian reserve after endometrioma-cystectomy.
Atsushi Yabuki; Ayako Muraoka; Satoko Osuka; Akira Yokoi; Kosuke Yoshida; Masami Kitagawa; Bayasura; Reina Sonehara; Natsuki Miyake; Natsuki Nakanishi; Tomoko Nakamura; Akira Iwase; Hiroaki Kajiyama
Reproductive biology, Mar. 2024
24(1), 100821, 100821, 10.1016/j.repbio.2023.100821

Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology.
Ayako Muraoka; Akira Yokoi; Kosuke Yoshida; Masami Kitagawa; Eri Asano-Inami; Mayuko Murakami; Bayasula; Natsuki Miyake; Natsuki Nakanishi; Tomoko Nakamura; Satoko Osuka; Akira Iwase; Hiroaki Kajiyama
Communications medicine, Feb. 2024
4(1), 33, 33, 10.1038/s43856-024-00460-8

★Upregulated Ribosomal Pathway Impairs Follicle Development in a Polycystic Ovary Syndrome Mouse Model: Differential Gene Expression Analysis of Oocytes.
Natsuki Nakanishi; Satoko Osuka; Tomohiro Kono; Hisato Kobayashi; Shinya Ikeda; Bayasula Bayasula; Reina Sonehara; Mayuko Murakami; Sayako Yoshita; Natsuki Miyake; Ayako Muraoka; Yukiyo Kasahara; Tomohiko Murase; Tomoko Nakamura; Maki Goto; Akira Iwase; Hiroaki Kajiyama
Reproductive sciences (Thousand Oaks, Calif.), Apr. 2023
30(4), 1306, 1315, 10.1007/s43032-022-01095-7

Unkeito promotes follicle development by restoring reduced follicle-stimulating hormone responsiveness in rats with polycystic ovary syndrome.
Sayako Yoshita; Satoko Osuka; Tomofumi Shimizu; Naoki Fujitsuka; Chinami Matsumoto; Bayasula; Natsuki Miyake; Ayako Muraoka; Natsuki Nakanishi; Tomoko Nakamura; Maki Goto; Hiroaki Kajiyama
Frontiers in endocrinology, 2023
14, 1228088, 1228088, 10.3389/fendo.2023.1228088

Tamoxifen Activates Dormant Primordial Follicles in Mouse Ovaries.
Wei Wei; Kouji Komatsu; Satoko Osuka; Tomohiko Murase; Bayasula Bayasula; Natsuki Nakanishi; Tomoko Nakamura; Maki Goto; Akira Iwase; Satoru Masubuchi; Hiroaki Kajiyama
Reproductive sciences (Thousand Oaks, Calif.), Dec. 2022
29(12), 3404, 3412, 10.1007/s43032-022-00896-0

Predictive factors for massive hemorrhage in women with retained products of conception: a prospective study.
Reina Sonehara; Tomoko Nakamura; Akira Iwase; Kazuki Nishida; Sachiko Takikawa; Mayuko Murakami; Sayako Yoshita; Ayako Muraoka; Natsuki Miyake; Natsuki Nakanishi; Satoko Osuka; Maki Goto; Hiroaki Kajiyama
Scientific reports, Jul. 2022
12(1), 11859, 11859, 10.1038/s41598-022-15564-1

Effectiveness of NLRP3 Inhibitor as a Non-Hormonal Treatment for ovarian endometriosis.
Mayuko Murakami; Satoko Osuka; Ayako Muraoka; Shotaro Hayashi; Bayasula; Yukiyo Kasahara; Reina Sonehara; Yumi Hariyama; Kanako Shinjo; Hideaki Tanaka; Natsuki Miyake; Sayako Yoshita; Natsuki Nakanishi; Tomoko Nakamura; Maki Goto; Hiroaki Kajiyama
Reproductive biology and endocrinology : RB&E, Mar. 2022
20(1), 58, 58, 10.1186/s12958-022-00924-3

Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells.
Natsuki Miyake; Takashi Nagai; Hidetaka Suga; Satoko Osuka; Takatoshi Kasai; Mayu Sakakibara; Mika Soen; Hajime Ozaki; Tsutomu Miwata; Tomoyoshi Asano; Mayuko Kano; Ayako Muraoka; Natsuki Nakanishi; Tomoko Nakamura; Maki Goto; Yoshinori Yasuda; Yohei Kawaguchi; Takashi Miyata; Tomoko Kobayashi; Mariko Sugiyama; Takeshi Onoue; Daisuke Hagiwara; Shintaro Iwama; Akira Iwase; Naoko Inoshita; Hiroshi Arima; Hiroaki Kajiyama
Endocrinology, Mar. 2022
163(3), 10.1210/endocr/bqac004

Impact of perioperative use of GnRH agonist or dienogest on ovarian reserve after cystectomy for endometriomas: a randomized controlled trial.
Ayako Muraoka; Satoko Osuka; Atsushi Yabuki; Bayasula; Masato Yoshihara; Hideaki Tanaka; Reina Sonehara; Natsuki Miyake; Mayuko Murakami; Sayako Yoshita; Natsuki Nakanishi; Tomoko Nakamura; Maki Goto; Akira Iwase; Hiroaki Kajiyama
Reproductive biology and endocrinology : RB&E, Dec. 2021
19(1), 179, 179, 10.1186/s12958-021-00866-2

Primate-specific POTE-actin gene could play a role in human folliculogenesis by controlling the proliferation of granulosa cells.
Yukiyo Kasahara; Satoko Osuka; Nobuyoshi Takasaki; Bayasula; Yoshihiro Koya; Natsuki Nakanishi; Tomohiko Murase; Tomoko Nakamura; Maki Goto; Akira Iwase; Hiroaki Kajiyama
Cell death discovery, Jul. 2021
7(1), 186, 186, 10.1038/s41420-021-00566-1

Very Low Levels of Serum Anti-Müllerian Hormone as a Possible Marker for Follicle Growth in Patients with Primary Ovarian Insufficiency Under Hormone Replacement Therapy.
Yukiyo Kasahara; Satoko Osuka; Bayasula; Natsuki Nakanishi; Tomohiko Murase; Tomoko Nakamura; Maki Goto; Tomomi Kotani; Akira Iwase; Fumitaka Kikkawa
Reproductive sciences (Thousand Oaks, Calif.), Jan. 2021
28(1), 31, 36, 10.1007/s43032-020-00278-4

Involvement of Transcription Factor 21 in the Pathogenesis of Fibrosis in Endometriosis.
Umida Ganieva; Tomoko Nakamura; Satoko Osuka; Bayasula; Natsuki Nakanishi; Yukiyo Kasahara; Nobuyoshi Takasaki; Ayako Muraoka; Shotaro Hayashi; Takashi Nagai; Tomohiko Murase; Maki Goto; Akira Iwase; Fumitaka Kikkawa
The American journal of pathology, Jan. 2020
190(1), 145, 157, 10.1016/j.ajpath.2019.09.008

Effect of the neuropeptide phoenixin and its receptor GPR173 during folliculogenesis.
Xuan Phuoc Nguyen; Tomoko Nakamura; Satoko Osuka; Bayasula Bayasula; Natsuki Nakanishi; Yukiyo Kasahara; Ayako Muraoka; Shotaro Hayashi; Takashi Nagai; Tomohiko Murase; Maki Goto; Akira Iwase; Fumitaka Kikkawa
Reproduction (Cambridge, England), Jul. 2019
158(1), 25, 34, 10.1530/REP-19-0025

Molecular mechanism of FSHR expression induced by BMP15 in human granulosa cells.
Ken Shimizu; Tomoko Nakamura; Bayasula; Natsuki Nakanishi; Yukiyo Kasahara; Takashi Nagai; Tomohiko Murase; Satoko Osuka; Maki Goto; Akira Iwase; Fumitaka Kikkawa
Journal of assisted reproduction and genetics, Jun. 2019
36(6), 1185, 1194, 10.1007/s10815-019-01469-y

★Animal models of polycystic ovary syndrome: A review of hormone-induced rodent models focused on hypothalamus-pituitary-ovary axis and neuropeptides.
Satoko Osuka; Natsuki Nakanishi; Tomohiko Murase; Tomoko Nakamura; Maki Goto; Akira Iwase; Fumitaka Kikkawa
Reproductive medicine and biology, Apr. 2019
18(2), 151, 160, 10.1002/rmb2.12262